Show simple item record

dc.contributor.authorMikkelsen, Mari
dc.contributor.authorWilsgaard, Tom
dc.contributor.authorGrimsgaard, Sameline
dc.contributor.authorHopstock, Laila Arnesdatter
dc.contributor.authorHansson, Patrik
dc.date.accessioned2023-08-07T11:14:45Z
dc.date.available2023-08-07T11:14:45Z
dc.date.issued2023-06-15
dc.description.abstractIntroduction: Elevated serum triglyceride concentrations increase the risk of developing atherosclerosis, the leading cause of cardiovascular disease. Postprandial triglyceride concentrations have shown to be a stronger predictor of cardiovascular disease compared to fasting triglycerides. It is therefore clinically relevant to study patterns of postprandial triglyceride concentrations in a general adult population.<p> <p>Aims: The aim of this cross-sectional analysis was to examine postprandial triglyceride concentrations in women and men, and the association with age, body mass index and menopausal status.<p> <p>Methods: Non-fasting blood samples from 20,963 women and men aged 40 years and older, attending the seventh survey of the Tromsø Study (2015–2016), were analyzed for postprandial triglyceride concentrations using descriptive statistics and linear regression models. Self-reported time since last meal before blood sampling was categorized into 1-h intervals with 7+ hours considered fasting.<p> <p>Results: Men had higher triglyceride concentrations compared to women. The pattern of postprandial triglyceride concentrations differed between the sexes. In women, the highest triglyceride concentration (19% higher compared to fasting level, p < 0.001) was found 3–4 h postprandially compared to 1–3 h in men (30% higher compared to fasting level, p < 0.001). In women, all subgroups of age and BMI had higher triglyceride concentrations than the reference group (age 40–49 years and BMI < 25 kg/m2), but no linear trend for age was observed. In men, triglyceride concentrations were inversely associated with age. Body mass index was positively associated with triglyceride concentration in both women (p < 0.001) and men (p < 0.001), although this association was somewhat modified by age in women. Postmenopausal women had significantly higher triglyceride concentrations compared to premenopausal women (p < 0.05).<p> <p>Conclusion: Postprandial triglyceride concentrations differed in groups of sex, age, body mass index, and menopausal status.en_US
dc.identifier.citationMikkelsen, Wilsgaard, Grimsgaard, Hopstock, Hansson. Associations between postprandial triglyceride concentrations and sex, age, and body mass index: cross-sectional analyses from the Tromsø study 2015–2016. Frontiers in Nutrition. 2023;10en_US
dc.identifier.cristinIDFRIDAID 2163659
dc.identifier.doi10.3389/fnut.2023.1158383
dc.identifier.issn2296-861X
dc.identifier.urihttps://hdl.handle.net/10037/29748
dc.language.isoengen_US
dc.publisherPublic Library of Scienceen_US
dc.relation.journalFrontiers in Nutrition
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleAssociations between postprandial triglyceride concentrations and sex, age, and body mass index: cross-sectional analyses from the Tromsø study 2015–2016en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US


File(s) in this item

Thumbnail

This item appears in the following collection(s)

Show simple item record

Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)