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dc.contributor.authorvan der Westhuizen, Danielle
dc.contributor.authorCastro, Abril C
dc.contributor.authorHazari, Nilay
dc.contributor.authorGevorgyan, Ashot
dc.date.accessioned2023-12-01T12:19:28Z
dc.date.available2023-12-01T12:19:28Z
dc.date.issued2023-10-30
dc.description.abstractIn recent years, considerable progress has been made in the conversion of biomass into renewable chemicals, yet the range of value-added products that can be formed from biomass remains relatively small. Herein, we demonstrate that molecules available from biomass serve as viable starting materials for the synthesis of phosphine ligands, which can be used in homogeneous catalysis. Specifically, we prepared renewable analogues of Beller's ligand (di(1-adamantyl)-n-butylphosphine, cataCXium® A), which is widely used in homogeneous catalysis. Our new renewable phosphine ligands facilitate Pd-catalysed Suzuki– Miyaura, Stille, and Buchwald–Hartwig coupling reactions with high yields, and our catalytic results can be rationalized based on the stereoelectronic properties of the ligands. The new phosphine ligands generate catalytic systems that can be applied for the late-stage functionalization of commercial drugs.en_US
dc.identifier.citationvan der Westhuizen, Castro, Hazari, Gevorgyan. Bulky, electron-rich, renewable: analogues of Beller's phosphine for cross-couplings. Catalysis Science & Technology. 2023en_US
dc.identifier.cristinIDFRIDAID 2202751
dc.identifier.doi10.1039/d3cy01375h
dc.identifier.issn2044-4753
dc.identifier.issn2044-4761
dc.identifier.urihttps://hdl.handle.net/10037/31901
dc.language.isoengen_US
dc.publisherRoyal Society of Chemistryen_US
dc.relation.journalCatalysis Science & Technology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleBulky, electron-rich, renewable: analogues of Beller's phosphine for cross-couplingsen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)