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dc.contributor.authorÖberg, Eva Gunnel Johanna
dc.contributor.authorJorde, Rolf
dc.contributor.authorAlmås, Bjørg
dc.contributor.authorNielsen, Christopher Sivert
dc.contributor.authorGerds, Thomas Alexander
dc.contributor.authorCashman, Kevin D.
dc.contributor.authorGrimnes, Guri
dc.date.accessioned2024-02-20T08:25:15Z
dc.date.available2024-02-20T08:25:15Z
dc.date.issued2023-11-13
dc.description.abstractContext: Longitudinal data regarding vitamin D status in adolescence is scarce. This study presents population-based data from an Arctic adolescent population (n = 589) at 16 and 18 years. Objective: The aims of this study were to investigate changes in vitamin D status during 2 years in adolescence, and whether lifestyle changes were associated with serum 25-hydroxyvitamin D (s-25(OH)D) at follow-up. <p><p>Methods: Fit Futures is a longitudinal study at 69°N in Norway. Participants had their s-25(OH)D levels analyzed in their first and third year of upper secondary school (median age 16 and 18 years), in Fit Futures 1 (FF1) and Fit Futures 2 (FF2), respectively. Self-reported lifestyle habits were registered through questionnaires. The association between lifestyle changes and s-25(OH)D levels at follow-up were calculated by regression analyses, controlling for baseline s-25(OH)D levels. <p>Results: Longitudinal data were available for 309 girls and 280 boys. The proportion of adolescents with s-25(OH)D <50 nmol/L were 73.7% in FF1 and 77.1% in FF2, while the proportion <30 nmol/L constituted 35.7% in FF1 and 40.9% in FF2. Of those with s-25(OH)D <30 nmol/L (severe vitamin D deficiency) in FF1, 73.3% remained severely deficient in FF2. Among boys, an increase in UV exposure was significantly associated with higher s-25(OH)D levels in FF2 (beta; CI [nmol/L] 12.9; 9.1, 16.7). In girls, decreased vitamin/mineral supplement intake was significantly associated with lower s-25(OH)D at FF2 (−6.7; −10.2, −3.1), while increased UV (10.8; 7.0, 14.7) and combined hormonal contraceptive exposure (12.1; 6.0, 18.1) in FF2 was significantly associated with higher s-25(OH)D levels in FF2. <p>Conclusion: Severe vitamin D deficiency was prevalent throughout adolescence. Lifestyle changes may alter s-25(OH)D levels in this age group.en_US
dc.identifier.citationÖberg, Jorde, Almås, Nielsen, Gerds, Cashman, Grimnes. Vitamin D Status During Adolescence and the Impact of Lifestyle Changes: 2 Years’ Follow-up From the Fit Futures Study. Journal of Clinical Endocrinology and Metabolism (JCEM). 2023;00:1-11en_US
dc.identifier.cristinIDFRIDAID 2247405
dc.identifier.doi10.1210/clinem/dgad655
dc.identifier.issn0021-972X
dc.identifier.issn1945-7197
dc.identifier.urihttps://hdl.handle.net/10037/32985
dc.language.isoengen_US
dc.publisherOxford University Pressen_US
dc.relation.journalJournal of Clinical Endocrinology and Metabolism (JCEM)
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleVitamin D Status During Adolescence and the Impact of Lifestyle Changes: 2 Years’ Follow-up From the Fit Futures Studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
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