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dc.contributor.authorRognli, Eline B.
dc.contributor.authorHeiberg, Ina Heidi
dc.contributor.authorJacobsen, Bjarne Koster
dc.contributor.authorHøye, Anne
dc.contributor.authorBramness, Jørgen Gustav
dc.date.accessioned2024-02-21T12:15:08Z
dc.date.available2024-02-21T12:15:08Z
dc.date.issued2023-05-03
dc.description.abstractObjective: The authors investigated transitions to schizophrenia spectrum or bipolar disorder following different types of substance-induced psychosis and the impact of gender, age, number of emergency admissions related to substance-induced psychosis, and type of substance-induced psychosis on such transitions. <p> <p>Methods: All patients in the Norwegian Patient Registry with a diagnosis of substance-induced psychosis from 2010 to 2015 were included (N=3,187). The Kaplan-Meier method was used to estimate cumulative transition rates from substance-induced psychosis to either schizophrenia spectrum disorder or bipolar disorder. Cox proportional hazard regression was used to estimate hazard ratios for transitions to schizophrenia spectrum or bipolar disorders associated with gender, age, number of emergency admissions, and type of substance-induced psychosis. <p> <p>Results: The 6-year cumulative transition rate from substance-induced psychosis to schizophrenia spectrum disorder was 27.6% (95% CI=25.6–29.7). For men, the risk of transition was higher among younger individuals and those with either cannabis-induced psychosis or psychosis induced by multiple substances; for both genders, the risk of transition was higher among those with repeated emergency admissions related to substance-induced psychosis. The cumulative transition rate from substance-induced psychosis to bipolar disorder was 4.5% (95% CI=3.6–5.5), and the risk of this transition was higher for women than for men. <p> <p>Conclusions: Transition rates from substance-induced psychosis to schizophrenia spectrum disorder were six times higher than transition rates to bipolar disorder. Gender, age, number of emergency admissions, and type of substance-induced psychosis affected the risk of transition.en_US
dc.identifier.citationRognli EB, Heiberg, Jacobsen, Høye, Bramness. Transition From Substance-Induced Psychosis to Schizophrenia Spectrum Disorder or Bipolar Disorder. American Journal of Psychiatry. 2023;180(6):437-444en_US
dc.identifier.cristinIDFRIDAID 2152340
dc.identifier.doi10.1176/appi.ajp.22010076
dc.identifier.issn0002-953X
dc.identifier.issn1535-7228
dc.identifier.urihttps://hdl.handle.net/10037/32997
dc.language.isoengen_US
dc.publisherAmerican Psychiatric Association Publishingen_US
dc.relation.journalAmerican Journal of Psychiatry
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.titleTransition From Substance-Induced Psychosis to Schizophrenia Spectrum Disorder or Bipolar Disorderen_US
dc.type.versionacceptedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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