Now showing items 1121-1140 of 1899

    • Identifying and correcting epigenetics measurements for systematic sources of variation 

      Perrier, Flavie; Novoloaca, Alexei; Ambatipudi, Srikant; Baglietto, Laura; Ghantous, Akram; Perduca, Vittorio; Barrdahl, Myrto; Harlid, Sophia; Ong, Ken K; Cardona, Alexia; Polidoro, Silvia; Nøst, Therese Haugdahl; Overvad, Kim; Omichessan, Hanane; Dollé, Martijn; Bamia, Christina; Huerta, José María; Vineis, Paolo; Herceg, Zdenko; Romieu, Isabelle; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-21)
      <i>Background</i>: Methylation measures quantified by microarray techniques can be affected by systematic variation due to the technical processing of samples, which may compromise the accuracy of the measurement process and contribute to bias the estimate of the association under investigation. The quantification of the contribution of the systematic source of variation is challenging in datasets ...
    • The management of acute myocardial infarction in the Russian Federation: Protocol for a study of patient pathways [version 2; referees: 2 approved] 

      Kontsevaya, Anna V; Bobrova, Natalia; Barbarash, Olga; Duplyakov, Dmitry; Efanov, Alexey; Galyavich, Albert; Frants, Maria; Khaisheva, Larisa; Malorodova, Tatyana; Mirolyubova, Olga; Nedbaikin, Andrei; Osipova, Irina; Platonov, Dmitry; Posnenkova, OIga; Syromiatnikova, Liudmila; Bates, Katie; Leon, David Adrew; McKee, Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-06)
      <i>Background</i>: Death rates from cardiovascular disease in Russia are among the highest in the world. In recent years, the Russian government has invested substantially in the healthcare system, with a particular focus on improving access to advanced technology, especially for acute myocardial infarction (AMI). This protocol describes a study to understand the management of AMI in different Russian ...
    • Adverse Pregnancy Outcomes among Adolescents in Northwest Russia: A Population Registry-Based Study 

      Usynina, Anna Aleksandrovna; Postoev, Vitaly; Odland, Jon Øyvind; Grjibovski, Andrej (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-03)
      This study aimed to assess whether adolescents have an increased risk of adverse pregnancy outcomes (APO) compared to adult women. We used data on 43,327 births from the population-based Arkhangelsk County Birth Registry, Northwest Russia, for 2012–2014. The perinatal outcomes included stillbirth, preterm birth (<37 and <32 weeks), low and very low birthweight, 5 min Apgar score <7 and <4, ...
    • Bone mineral density at the hip and its relation to fat mass and lean mass in adolescents: the Tromsø Study, Fit Futures 

      Winther, Anne; Jørgensen, Lone; Ahmed, Luai A.; Christoffersen, Tore; Furberg, Anne-Sofie; Grimnes, Guri; Jorde, Rolf; Nilsen, Ole-Andreas; Dennison, Elaine M.; Emaus, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-19)
      <p><i>Background</i>: Positive association between body weight and bone mass is well established, and the concept of body mass index (BMI) is associated with higher areal bone mineral density (aBMD) and reduced fracture risk. BMI, that comprises both fat mass (FM) and lean mass (LM) may contribute to peak bone mass achievement in different ways. This study explored the influence of body composition ...
    • Seroprevalence of markers of hepatitis B virus infection, associated factors, and vaccination status in young adults in Arkhangelsk, Northwest Russia: A population-based cross-sectional study 

      Balaeva, Tatyana Viktorovna; Grjibovski, Andrei M.; Samodova, Olga; Sannikov, Anatoly; Klouman, Elise (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-01)
      Russia had a high incidence of hepatitis B virus (HBV) infection before the vaccination campaigns of 1997, 2001, 2007, which targeted newborns, adolescents, and adults, respectively. The aim of our study was to assess the prevalence of serological markers of HBV infection, associated factors, and vaccination status among young adults in Arkhangelsk, Northwest Russia. In this cross-sectional, p ...
    • Prenatal Exposure to Aluminum and Status of Selected Essential Trace Elements in Rural South AfricanWomen at Delivery 

      Rollin, Halina B.; Nogueira, Claudina; Olutola, Bukola G; Channa, Kalavati; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-15)
      This study sought to evaluate the in utero exposure to aluminum and status of selected trace elements in South African women at delivery since aluminum is known to be toxic in all developmental stages even at low concentrations. Serum aluminum was negatively correlated with aluminum in urine, both uncorrected and corrected for creatinine, which suggests the retention of aluminum in body stores. ...
    • Designing mHealth for maternity services in primary health facilities in a low-income setting - Lessons from a partially successful implementation 

      Shiferaw, Solomon; Workneh, Andualem; Yirgu, Robel; Dinant, Geert-Jan; Spigt, Marcus (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-12)
      <p><i>Background</i>: Increasing mobile phone ownership, functionality and access to mobile-broad band internet services has triggered growing interest to harness the potential of mobile phone technology to improve health services in low-income settings. The present project aimed at designing an mHealth system that assists midlevel health workers to provide better maternal health care services by ...
    • Tuberculosis treatment outcome and predictors in northern Ethiopian prisons: A five-year retrospective analysis 

      Adane, Kelemework; Spigt, Marcus; Dinant, Geert-Jan (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-20)
      <p><i>Background</i>: The prison situations are notorious for causing interruptions of tuberculosis (TB) treatment and occurrence of unfavorable outcomes. In Ethiopian prisons, though TB treatment programs exist, treatment outcome results and factors contributing to unsuccessful outcome are not well documented. In this study, we assessed the treatment outcome of TB cases and identified risk factors ...
    • Risk Factors for Ventricular Septal Defects in Murmansk County, Russia: A Registry-Based Study 

      Kovalenko, Anton Alexandrovich; Anda, Erik Eik; Odland, Jon Øyvind; Nieboer, Evert; Brenn, Tormod; Krettek, Alexandra (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-24)
      Cardiovascular malformations are one of the most common birth defects among newborns and constitute a leading cause of perinatal and infant mortality. Although some risk factors are recognized, the causes of cardiovascular malformations (CVMs) remain largely unknown. In this study, we aim to identify risk factors for ventricular septal defects (VSDs) in Northwest Russia. The study population ...
    • Large-scale secretome analyses unveil the superior immunosuppresive phenotype of umbilical cord stromal cells as compared to other adult mesenchymal stromal cells 

      Islam, Md Ashraful; Urbarova, Ilona; Bruun, Jack-Ansgar; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-20)
      Mesenchymal stromal cells (MSCs), given their regenerative potential, are being investigated as a potential therapeutic tool for cartilage lesions. MSCs express several bioactive molecules which act in a paracrine fashion to modulate the tissue microenvironment. Yet, little is known about the divergence of these signalling molecules in different MSC populations. The present study investigated ...
    • Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes 

      Lofterød, Trygve; Mortensen, Elin Synnøve; Nalwoga, Hawa; Wilsgaard, Tom; Frydenberg, Hanne; Risberg, Terje; Eggen, Anne Elise; McTiernan, Anne; Aziz, Sura Mohammed; Wist, Erik; Stensvold, Andreas; Reitan, Jon Brinchmann; Akslen, Lars A.; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-15)
      <i>Background</i>: High triglycerides and low levels of high density lipoprotein (HDL)-cholesterol are observed to promote tumor growth. However, whether breast cancer heterogeneity may explain the contradictory influence of triglycerides and cholesterol observed on breast cancer prognosis remains unclear.<p> <p><i>Methods</i>: A population-based survival study among 464 breast cancer cases ...
    • "The prayer circles in the air": a qualitative study about traditional healer profiles and practice in Northern Norway 

      Larsen, Anette Langås; Salamonsen, Anita; Kristoffersen, Agnete Egilsdatter; Stub, Trine (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-31)
      In Northern Norway, traditional healing has been preserved by passing down the knowledge through generations. Religious prayers of healing (<i>reading</i>) and Sami rituals (<i>curing</i>) are examples of methods that are used. We have examined traditional healers’ understanding of traditional healing, the healing process and their own practice, as well as what characteristics healers should have. ...
    • Overall survival and time trends in breast and cervical cancer incidence and mortality in the Regional Health District (RHD) of Barretos, Sao Paulo, Brazil 

      Da Costa, Allini Mafra; Hashim, Dana; Fregnani, Jose Humberto; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-07)
      <p><i>Background</i>: Breast and cervical cancers represent a significant cause of morbidity and mortality among women. The purpose of this study was to analyse the survival and time trends in two of the most common female cancers in the Regional Health District (RHD) of Barretos, São Paulo, Brazil.</p> <p><i>Methods</i>: From 2000 through 2015, we calculated the breast and cervical cancer incidence ...
    • DNA methylation and associated gene expression in blood prior to lung cancer diagnosis in the Norwegian Women and Cancer cohort 

      Sandanger, Torkjel M; Nøst, Therese Haugdahl; Guida, Florence; Rylander, Charlotta; Campanella, Gianluca; Muller, David C; Van Dongen, Jenny; Boomsma, Dorret I; Johansson, Mattias; Vineis, Paolo; Vermeulen, Roel; Lund, Eiliv; Chadeau-Hyam, Marc (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-13)
      The majority of lung cancer is caused by tobacco smoking, and lung cancer-relevant epigenetic markers have been identified in relation to smoking exposure. Still, smoking-related markers appear to mediate little of the effect of smoking on lung cancer. Thus in order to identify disease-relevant markers and enhance our understanding of pathways, a wide search is warranted. Through an epigenome-wide ...
    • The ambiguity of physical activity, exercise and atrial fibrillation 

      Morseth, Bente; Løchen, Maja-Lisa; Ariansen, Inger Kristine Holtermann; Myrstad, Marius; Thelle, Dag Steinar (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-07)
      Although commonly associated with cardiovascular disease or other medical conditions, atrial fibrillation may also occur in individuals without any known underlying conditions. This manifestation of atrial fibrillation has been linked to extensive and long-term exercise, as prolonged endurance exercise has shown to increase prevalence and risk of atrial fibrillation. In contrast, more modest physical ...
    • The effect of smear layer removal on E. faecalis leakage and bond strength of four resin-based root canal sealers 

      Andriukaitiene, Laura; Song, Xiaobo; Yang, Nannan; Lippo V. J., Lassila; K. Vallittu, Pekka; Kerosuo, Eero (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-13)
      <p><i>Background</i>: The aim of the study was to assess bacterial sealability and bonding ability of methacrylate-based Resilon (RS, SybronEndo), Endo Rez (ER, Ultradent Products Inc), and epoxy-based AH Plus (AH, Dentsply/DeTrey), MTA Fill Apex (MTAF, Angelus Soluções Odontológicas) root canal sealers, and the effect of the smear layer removal on the sealability.</p> <p><i>Methods</i>: One ...
    • Haem iron intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Ward, Heather A; Whitman, Julia; Muller, David C; Johansson, Mattias; Jakszyn, Paula; Weiderpass, Elisabete; Palli, Domenico; Fanidi, Anouar; Vermeulen, Roel; Tjønneland, Anne; Hansen, Louise; Dahm, Christina C.; Overvad, Kim; Severi, Gianluca; Boutron-Ruault, Marie-Christine; Affret, Aurélie; Kaaks, Rudolf; Fortner, Renee; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Kotanidou, Anastasia; Berrino, Franco; Krogh, Vittorio; Tumino, Rosario; Ricceri, Fulvio; Panico, Salvatore; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Quirós, José Ramón; Agudo, Antonio; Rodríguez-Barranco, Miguel; Larrañaga, Nerea; Huerta, Jose Maria; Ardanaz, Eva; Drake, Isabel; Brunnström, Hans; Johansson, Mikael; Grankvist, Kjell; Travis, Ruth C.; Freisling, Heinz; Stepien, Magdalena; Merritt, Melissa A.; Riboli, Elio; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-18)
      <p><i>Background</i>: Epidemiological studies suggest that haem iron, which is found predominantly in red meat and increases endogenous formation of carcinogenic N-nitroso compounds, may be positively associated with lung cancer. The objective was to examine the relationship between haem iron intake and lung cancer risk using detailed smoking history data and serum cotinine to control for potential ...
    • Timing of eating across ten European countries - Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study 

      Huseinovic, Ena; Winkvist, Anna; Freisling, Heinz; Slimani, Nadia; Boeing, Heiner; Buckland, Genevieve; Schwingshackl, Lukas; Olsen, Anja; Tjønneland, Anne; Stepien, Magdalena; Boutron-Ruault, Marie-Christine; Mancini, Francesca; Artaud, Fanny; Kühn, Tilman; Katzke, Verena; Trichopoulou, Antonia; Naska, Androniki; Orfanos, Philippos; Tumino, Rosario; Masala, Giovanna; Krogh, Vittorio; Santucci De Magistris, Maria; Ocké, Marga C.; Brustad, Magritt; Enget Jensen, Torill; Skeie, Guri; Rodriguez-Barranco, Miguel; Huerta, José María; Ardanaz, Eva; Quirós, José Ramón; Jakszyn, Paula; Sonestedt, Emily; Ericson, Ulrika; Wennberg, Maria; Key, Timothy J.; Aune, Dagfinn; Riboli, Elio; Weiderpass, Elisabete; Berteus Forslund, Helene (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-17)
      <p><i>Objective</i>: To examine timing of eating across ten European countries.</p> <p><i>Design</i>: Cross-sectional analysis of the European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study using standardized 24 h diet recalls collected during 1995–2000. Eleven predefined food consumption occasions were assessed during the recall interview. We present time of consumption ...
    • Mild cognitive impairment impacts health outcomes of patients with atrial fibrillation undergoing a disease management intervention 

      Ball, Jocasta; Løchen, Maja-Lisa; Carrington, Melinda; Wiley, Joshua F; Stewart, Simon (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-07)
      <p><i>Objective</i>: Mild cognitive impairment (MCI) is prevalent in atrial fibrillation (AF) and has the potential to contribute to poor outcomes. We investigated the influence of MCI on survival and rehospitalisation in patients with chronic forms of AF undergoing a home-based, AF-specific disease management intervention (home-based intervention (HBI)) or standard management (SM).</p> <p><i>M ...
    • Milk and risk of colorectal, colon and rectal cancer in the Norwegian Women and Cancer (NOWAC) Cohort Study 

      Bakken, Toril; Braaten, Tonje; Olsen, Anja; Hjartåker, Anette; Lund, Eiliv; Skeie, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-17)
      According to World Cancer Research Fund International/American Institute for Cancer Research, it is ‘probable’ that dairy products decrease the risk of colorectal cancer (CRC). However, meta-analyses restricted to women have not shown associations between milk intake and risk of CRC. The aim of this study was to examine the association between milk intake and risk of CRC, colon cancer and rectal ...