Now showing items 801-820 of 1899

    • Why does Russia have such high cardiovascular mortality rates? Comparisons of blood-based biomarkers with Norway implicate non-ischaemic cardiac damage 

      Iakunchykova, Olena; Averina, Maria; Wilsgaard, Tom; Watkins, Hugh; Malyutina, Sofia; Ragino, Yulia; Keogh, Ruth; Kudryavtsev, Alexander V; Govorun, Vadim; Cook, Sarah Anne; Schirmer, Henrik; Eggen, Anne Elise; Hopstock, Laila Arnesdatter; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-15)
      <p><i>Background - </i>Russia has one of the highest rates of mortality from cardiovascular disease (CVD). At age 35–69 years, they are eight times higher than in neighbouring Norway. Comparing profiles of blood-based CVD biomarkers between these two populations can help identify reasons for this substantial difference in risk. <p><i>Methods - </i>We compared age-standardised mean levels of CVD ...
    • Physical activity and blood gene expression profiles: the Norwegian Women and Cancer (NOWAC) Post-genome cohort 

      Olsen, Karina Standahl; Lukic, Marko; Borch, Kristin Benjaminsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-11)
      <i>Objectives</i> - The influence of physical activity (PA) on the immune system has emerged as a new field of research. Regular PA may promote an anti-inflammatory state in the body, thus contributing to the down-regulation of pro-inflammatory processes related to the onset and progression of multiple diseases. We aimed to assess whether overall PA levels were associated with differences in blood ...
    • Use of group based trajectory modelling to identify groups based on trajectories obtained for overall number of antibiotics prescription to children age 0-3 years in Norway during year 2004 to 2017 

      Tanwar, Bhupender Singh (Master thesis; Mastergradsoppgave, 2020-12-01)
      Bacterial infection occur frequently in children. In 2015 more than 900,000 children below 5 years were killed due to respiratory tract infections (RTIs). Early life onset and prolonged use of antibiotics in children can leads to health complications later in life. Antibiotics prescribing in young children is affected by many factors and identifying these factors can provide an opportunity to develop ...
    • Carotid intima media thickness in older childrenand adolescents with HIV taking antiretroviraltherapy 

      Majonga, Edith D.; Chiesa, Scott T.; McHough, Grace; Mujuru, Hilda; Nathoo, Kusum; Odland, Jon Øyvind; Kaski, Juan Pablo; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04)
      Increased carotid intima-media thickness (cIMT) is reported in both adults and children with human immunodeficiency virus (HIV) in high income settings and is associated with an increased risk of cardiovascular disease, but data from sub-Saharan Africa is lacking.<p> <p>We assessed cIMT using ultrasound in perinatally HIV-infected children aged 6 to 16 years taking antiretroviral therapy (ART) ...
    • Sex-specific associations between oral health and cardiovascular risk profile in the population-based Tromsø Study 7 

      Elawady, Ahmed (Master thesis; Mastergradsoppgave, 2020-12-04)
      Introduction: cardiovascular disease (CVD) is one of the major causes of death in the world. Many studies have linked CVD with periodontitis which is oral inflammatory disease. But those studies didn´t take into consideration the overall oral health as one confounder that can be linked to CVD, not just periodontitis. Objective: the main aim was to study the sex-specific association between variables ...
    • Association between diabetes and periodontitis: A cross sectional study based on findings from Tromsø 7 study 

      Alex, Silvi (Master thesis; Mastergradsoppgave, 2020-11-30)
      The 2017 reports published by Diabetesforbundet Norway showed an estimated 378 000 people living with diabetes (28 000 with Type 1 and 350 000 with Type 2). Mealey et al. (2006) showed that diabetes increases the risk for periodontitis, influenced by inflammatory processes. The formation of inflammatory molecules (e.g. Advanced glycation end products) leads to gingival attachment loss, periodontal ...
    • GP decisions to participate in emergencies: a randomised vignette study 

      Hjortdahl, Magnus; Gyrd-Hansen, Dorte; Halvorsen, Peder Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-19)
      <i>Background</i> - GPs use their judgement on whether to participate in emergencies; however, little is known about how GPs make their decisions on emergency participation.<p> <p><i>Aim</i> - To test whether GPs' participation in emergencies is associated with cause of symptoms, distance to the patient, other patients waiting, and out-of-hours (OOH) clinic characteristics.<p> <p><i>Design & ...
    • Disparities amidst plenty: a health portrait of Indigenous peoples in circumpolar regions 

      Young, T. Kue; Broderstad, Ann Ragnhild; Sumarokov, Yury; Bjerregaard, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-30)
      This paper describes the extent and variation in health disparities between Indigenous and non-Indigenous people within Alaska, Greenland and the northern regions of Canada, Russia and the Nordic countries. We accessed official health statistics and reviewed research studies. We selected a few indicators of health status, health determinants and health care to demonstrate the health disparities that ...
    • Factors Associated with Cesarean Section among Primiparous Women in Georgia: A Registry-based Study 

      Nedberg, Ingvild Hersoug; Rylander, Charlotta; Skjeldestad, Finn Egil; Blix, Ellen; Ugulava, Tamar; Anda, Erik Eik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-21)
      Cesarean section rates remain high in Georgia. As a cesarean section in the first pregnancy generally lead to a cesarean section in subsequent pregnancies, primiparous women should be targeted for prevention strategies. The aim of the study was to assess factors associated with cesarean section among primiparous women. The study comprised 17,065 primiparous women with singleton, cephalic deliveries ...
    • Factors associated with exclusive breastfeeding at hospital discharge: a study using data from the Georgian Birth Registry 

      Sigstad, Marie; Nedberg, Ingvild Hersoug; Anda, Erik Eik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-13)
      <p><i>Background - </i>The World Health Organization recommends exclusive breastfeeding for six months, defined as no other solids or liquids besides breast milk and essential vitamins or medicines. Data about exclusive breastfeeding are limited in Georgia, and the information that exist are provided by national surveys, that present inconsistent numbers. Georgia has recently established a national ...
    • Red Cell Distribution Width and Risk of Atrial Fibrillation and Subsequent Thromboembolism: The Tromsø Study 

      Hald, Erin Mathiesen; Løchen, Maja-Lisa; Lappegård, Jostein; Ellingsen, Trygve; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Njølstad, Inger; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-28)
      <i>Introduction</i>- Red cell distribution width (RDW) is associated with cardiovascular diseases, including atrial fibrillation (AF) and venous thromboembolism (VTE). Whether RDW is a risk marker for thromboembolic events in AF patients is scarcely known. We aimed to assess the association between RDW and the risk of AF, and AF-related VTE and ischemic stroke, in a population-based cohort.<p> ...
    • Quantifying the contribution of established risk factors to cardiovascular mortality differences between Russia and Norway 

      Trias-Llimós, Sergi; Pennells, Lisa; Tverdal, Aage; Kudryavtsev, Alexander V; Malyutina, Sofia; Hopstock, Laila Arnesdatter; Iakunchykova, Olena; Nikitin, Yuri; Magnus, Per; Kaptoge, Stephen; Di Angelantonio, Emanuele; Leon, David A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-27)
      Surprisingly few attempts have been made to quantify the simultaneous contribution of well-established risk factors to CVD mortality differences between countries. We aimed to develop and critically appraise an approach to doing so, applying it to the substantial CVD mortality gap between Russia and Norway using survey data in three cities and mortality risks from the Emerging Risk Factor Collaboration. ...
    • Mangfoldsperspektiver i forskning på vold i nære relasjoner 

      Bredal, Anja; Eggebø, Helga; Eriksen, Astrid (Chapter; Bokkapittel, 2020-06-10)
      Most research on domestic violence has focused on violence against women in a gender perspective. However, there has been an increasing understanding of the importance of other social dimensions in order to understand the nature and impact of the violence. The aim of this chapter is to explore the current status of research on domestic violence in a diversity perspective. We argue that dimensions like ...
    • Plan, recruit, retain: a framework for local healthcare organizations to achieve a stable remote rural workforce 

      Abelsen, Birgit; Strasser, Roger; Heaney, David; Berggren, Peter; Sigurðsson, Sigurður; Brandstorp, Helen; Wakegijig, Jennifer; Forsling, Niclas; Moody-Corbett, Penny; Akearok, Gwen Healey; Mason, Anne; Savage, Claire; Nicoll, Pam (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-03)
      <i>Background</i> - Recruiting and retaining a skilled health workforce is a common challenge for remote and rural communities worldwide, negatively impacting access to services, and in turn peoples’ health. The research literature highlights different factors facilitating or hindering recruitment and retention of healthcare workers to remote and rural areas; however, there are few practical tools ...
    • Prediction of chronic heart failure and chronic obstructive pulmonary disease in a general population: the Tromsø study 

      Melbye, Hasse; Stylidis, Michael; Aviles Solis, Juan Carlos; Averina, Maria; Schirmer, Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-07)
      <i>Aims</i> - Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are main causes of dyspnoea, and echocardiography and spirometry are essential investigations for these diagnoses. Our aim was to determine the prevalence of HF and COPD in a general population, also how the diseases may be identified, and to what extent their clinical characteristics differ.<br><br> <i>Methods and ...
    • Genetic risk-factors for anxiety in healthy individuals: polymorphisms in genes important for the HPA axis 

      Lindholm, Heléne; Morrison, India; Krettek, Alexandra; Malm, Dan; Novembre, Giovanni; Handlin, Linda (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-21)
      <i>Background</i> - Two important aspects for the development of anxiety disorders are genetic predisposition and alterations in the hypothalamic-pituitary-adrenal (HPA) axis. In order to identify genetic risk-factors for anxiety, the aim of this exploratory study was to investigate possible relationships between genetic polymorphisms in genes important for the regulation and activity of the HPA ...
    • Have medical students’ attitudes towards clinical communication skills changed over a 12- year period? A comparative long-term study 

      Gude, Tore; Tyssen, Reidar; Anvik, Tor; Grimstad, Hilde; Holen, Are; Baerheim, Anders; Vaglum, Per Jørgen Wiggen; Løvseth, Lise T (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-10)
      <i>Background</i> - Attitudes towards learning clinical communication skills at the end of medical school are likely to reflect the students’ training and motivation for the continued development of their skills as doctors. Students from two Norwegian medical schools, one with a traditional, and the other with an integrated curriculum, were approached in 2003 and 2015; with regard to changes in ...
    • Adverse effects in homeopathy. A systematic review and meta-analysis of observational studies 

      Stub, Trine; Kristoffersen, Agnete Egilsdatter; Overvåg, Grete; Jong, Miek; Musial, Frauke; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-28)
      <p><i>Background - </i>Almost all health care interventions have the potential to be associated with risk to patient safety. Different terminologies are used to define treatment induced risk to patient safety and a common definition is the term adverse effect. Beyond the concept of adverse effect and specific to homeopathy is the concept of homeopathic aggravation. Homeopathic aggravation describes ...
    • Omega-3 polyunsaturated fatty acid supplementation and the risk of fatal myocardial infarction among Norwegian women: a prospective cohort 

      Rist, Kim (Master thesis; Mastergradsoppgave, 2020-12-01)
      <p>Background: In 2015, around 17.9 million people died from cardiovascular disease worldwide, with myocardial infarction being the most common manifestation. Contemporary research suggests that omega-3 (n-3) polyunsaturated fatty acid (PUFA) interventions have less useful cardiovascular outcomes than previously thought. This study aims to examine the association between n-3 PUFA intake frequency ...
    • Distribution of health anxiety in a general adult population and associations with demographic and social network characteristics 

      Norbye, Anja M. Davis; Abelsen, Birgit; Førde, Olav Helge; Ringberg, Unni (Journal article; Tidsskriftartikkel, 2020-11-13)
      <i>Background</i> - Health anxiety (HA) is associated with increased risk of disability, increased health care utilization and reduced quality of life. However, there is no consensus on which factors are important for the level of HA. The aim of this study was to explore the distribution of HA in a general adult population and to investigate whether demographic and social factors were associated ...