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norskInstitutt for samfunnsmedisin: Nye registreringer
Viser treff 1421-1440 av 2043
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DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-28)Aim of the study: A vast majority of human malignancies are associated with ageing, and age is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing, known as ‘epigenetic clock’, has been linked with cancer risk factors. This study aimed to evaluate whether the epigenetic clock is associated with breast cancer risk susceptibility and to identify potential epigenetics-based ... -
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-16)Background: <br> Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk ... -
General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): Study protocol for a randomised controlled trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-29)Background: <br>Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed an antibiotic, which may not always be appropriate and may cause harm. C-reactive protein (CRP) is an acute-phase biomarker that can be rapidly measured at the point of care and may predict benefit from antibiotic treatment in AECOPD. It is not clear ... -
Resting heart rate trajectories and myocardial infarction, atrial fibrillation, ischaemic stroke and death in the general population: The Tromso Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-25)Background: <br>Resting heart rate (RHR) is an established risk factor for cardiovascular disease (CVD), but long-term individual RHR trajectories and their effect on CVD morbidity and mortality have not yet been described. <br> Methods: <br>This large population-based longitudinal study included 14,208 men and women aged 20 years or older, not pregnant, and not using blood pressure medications, ... -
The impact of changes in leisure time physical activity on changes in cardiovascular risk factors: results from The Finnmark 3 Study and SAMINOR 1, 1987–2003
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-15)Objective: <br>The aim of this study was to examine the associations between changes in leisure time physical activity and changes in cardiovascular risk factors over 16 years and whether they differ between two ethnic groups in Norway. <br>Methods: <br>Data were extracted from two population-based studies. Altogether, 3671 men and women participated in both surveys, and 30% reported being of ... -
Prevalence and reasons for intentional use of complementary and alternative medicine as an adjunct to future visits to a medical doctor for chronic disease
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-27)Intentional use of complementary and alternative medicine (CAM) has previously only been researched in small, possibly biased, samples. There seems to be a lack of scientific information regarding healthy individual's attitudes and presumed use of CAM. The aim of this study is to describe prevalence and characteristics of participants who intend to see a CAM provider compared to participants who ... -
Attitudes and knowledge about direct and indirect risks among conventional and complementary health care providers in cancer care
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-31)Background: Many complementary therapies offer benefits for patients with cancer. Others may be risky for patients due to negative interactions with conventional treatment and adverse effects. Therefore, cancer patients need guidance from health care providers to assess complementary modalities appropriately to receive benefits and avoid harm. <br> Method: In a self-administered questionnaire-based ... -
Dental caries and preterm birth: a systematic review and meta-analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-02)Objectives:<br> The primary objective of this systematic review was to evaluate the association between dental caries and preterm birth (PTB). The secondary objective was ascertaining the difference between women with dental caries who experienced PTB and those who did not with regard to decayed, missing and filled teeth (DMFT), and decayed, missing and filled surfaces (DMFS) indices. <br>M ... -
Risk of early-onset prostate cancer associated with occupation in the Nordic countries
(Journal article; Tidsskriftartikkel, 2017-11-10)Background: <br>Early-onset prostate cancer is often more aggressive and may have a different etiology than later-onset prostate cancer, but has been relatively little studied to date. We evaluated occupation in relation to early-onset and later-onset prostate cancer in a large pooled study. <br>Methods: <br>We used occupational information from census data in five Nordic countries from 1960-1990. ... -
Avoidable cancer cases in the Nordic countries - The impact of overweight and obesity
(Journal article; Tidsskriftartikkel, 2017-05-03)Background: <br>Several types of cancers are causally linked to overweight and obesity which are increasing in the Nordic countries. The aim of this study was to quantify the proportion of the cancer burden linked to overweight and obesity in the Nordic countries and estimate the potential for cancer prevention.<br> Methods: <br>Under different prevalence scenarios of overweight and obesity, ... -
GP-confirmed complete Achilles tendon rupture using pocket-sized ultrasound: a case report
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-25)The incidence of complete Achilles tendon rupture is 18 per 100 000 patient-years and is usually diagnosed clinically by GPs. The extent of clinical misdiagnosis is unknown in Norway, but may be high. This is important as delayed treatment has unfavourable consequences. We report how a GP, with no clinical ultrasound experience, recorded images with a pocket-sized ultrasound device (PSUD) under ... -
Blood pressure target achievement and antihypertensive medication use in women and men after first-ever myocardial infarction: the Tromsø Study 1994-2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-03)Background: <br> Recurrent cardiovascular events after myocardial infarction (MI) are frequent, and gender differences in blood pressure treatment have been reported. Despite increased focus on secondary prevention, recent reports indicate that treatment targets are not achieved. There is a need for gender-specific analyses of post-MI blood pressure treatment target achievement and ... -
Yoik experiences and possible positive health outcomes: An explorative pilot study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-19)Background: Yoik is an old vocal music tradition of Sami, the indigenous people inhabiting Northern Fennoscandia and Kola peninsula in Russia. Studies of music therapy (MT) and especially singing have documented improvements in social and overall functioning in people With severe mental disorders and positive effect on depressive symptoms and sleep quality. Possible connections between yoik and ... -
Kreftdiagnostikk i almenpraksis VII. Ringeklokkesymptomer, ringeklokkedata og fallgruver. Nyttige varslere i almenpraktikerens kreftdiagnostiske arbeid?
(Journal article; Tidsskriftartikkel; Peer reviewed, 1984)Her presenteres lister over «ringeklokkesymptomer», «ringeklokkedata» og «fallgruver» i praktisk kreftdiagnostikk. Listene er ment å være forslag til en utdypet og forbedret legerettet versjon av de publikumsrettede kreftens syv faresignaler. <br>Forekomst av disse diagnostiske data er registrert ved journalgjennomgang for 65 kreftpasienter. Forekomst av ringeklokkesymptomer er også registrert hos ... -
Kreftdiagnostikk i almenpraksis VI. Innholdet i kreftfaresignalene. Er "varige smerter" aktuelt som faresignal?
(Journal article; Tidsskriftartikkel; Peer reviewed, 1984)Antallet og innholdet i kreftfaresignalene er blitt endret flere ganger siden de ble introdusert i USA under første verdenskrig. Faresignalene er forsøkt utformet slik at de hjelper mennesker med kreft til raskest mulig å søke lege, uten å skape unødig angst i befolkningen og øke "trivialitets"-belastningen i helsevesenet. <br> Her diskuteres denne målsetningen, og jeg undersøker nærmere ... -
Kreftdiagnostikk i almenpraksis V. Pasienter med og uten kreft. Hvem søker lege for kreftens syv faresignaler?
(Journal article; Tidsskriftartikkel; Peer reviewed, 1984)Almenpraktiker- og sykehusjournaler til 65 kreftpasienter og 65 kjønns- og aldersmessig like kontrollpasienter ble gjennomgått for å registrere forekomst av kreftens syv faresignaler. For kreftpasientene ble kun faresignaler som opptrådte før diagnose, registrert. og disse ble klassifisert som «tidlig» eller «sent» opptredende etter nærmere definisjoner. <br> Hos 66 % av kreftpasientene forekom ... -
Kreftdiagnostikk i almenpraksis IV. Intervjuregistrering av kreftfaresignaler. Pasienter i almenpraksis og befolkningen
(Journal article; Tidsskriftartikkel; Peer reviewed, 1984)Opplysning om kreftens syv faresignaler (tab 1) er rettet mot publikum. Informasjonen tar sikte på å få mennesker som opplever symptomer som passer med faresignalene, til å søke lege snarest mulig. Dør-til-dør-intervju med 299 personer i Tromsø viste at 74 (25 %) anga å ha opplevd faresignalsymptomer de siste tre månedene. Omtrent halvparten av de 74 hadde kontaktet lege av denne grunn. ... -
Kreftdiagnostikk i almenpraksis III. Almenpraktikeres registrering av kreftfaresignaler hos pasienter
(Journal article; Tidsskriftartikkel; Peer reviewed, 1984)Almenpraktikere i Tromsø registrerte i tiden 1/10 1981-31/3 1982 forekomsten av symptomer som samsvarer med kreftens syv faresignaler hos sine pasienter. Faresignal ble registrert ved 5,4 % av konsultasjonene. Forekomst av faresignaler pr. 1 000 konsultasjoner presenteres sammen med alders- og kjønnsfordeling. -
Kreftdiagnostikk i almenpraksis I. Kan diagnosen stilles tidligere?
(Journal article; Tidsskriftartikkel; Peer reviewed, 1980)108 pasienter ble i 1976 meldt til Kreftregisteret fra Tromsø kommune. Almenpraktiker- og sykehusjournaler for disse pasientene er gjennomgått og vurdert med tanke på hvor raskt kreftsykdommen ble diagnostisert.<br> Tre fjerdedeler av pasientene kunne ut fra en etterpåklok vurderlng fått stilt diagnosen tidligere. Halvparten av alle kom sent til lege, og for halvparten kunne almenpraktikere eller ... -
Salivary cortisol, perceived stress, and metabolic syndrome: a matched case-control study in female shift workers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-30)Objective: <br> Although the pathogenesis of metabolic syndrome (MetS) is complex and multifactorial, there is limited information if psychological factors, such as stress exposure, are involved in the etiology of MetS. Therefore, this study investigated the associations between MetS and cortisol levels and perceived stress levels among women shift workers in Southern Brazil.<br> Design: ...
