Background - Patients with multiple chronic conditions, for example, musculoskeletal conditions and comorbidities, often receive inadequate and sometimes even contradictory care. Physiotherapists are well qualified to manage patients with musculoskeletal conditions and comorbidities due to their education and experience with rehabilitation; however, it is unknown which challenges they face when ...

Objectives Investigate associations between body height and cardiovascular disease risk factors at several time points in women and men across educational levels in Norway.<p> <p>Design Population-based longitudinal study. <p>Setting The Tromsø Study, a population-based study with six surveys conducted between 1979 and 2016 in the municipality of Tromsø, Norway. <p>Primary and Secondary ...

Despite important progress in modern medicine, widely regarded as an indispensable foundation of healthcare in all highly advanced nations and regions, not all patients respond well to available treatments in biomedicine alone. Additionally, there are concerns about side effects of many medications and interventions, the unsustainable cost of healthcare and the low resolution of chronic non-communicable ...

Background - Migraine is a common disorder, particularly affecting women during their reproductive years. This female preponderance has been linked to exposure to female sex hormones.<p> <p>Methods - We used self-reported data from women born in 1943–1965 enrolled in the Norwegian Women and Cancer Study to examine the differences between women with migraine and women without migraine in a prospective ...

This article addresses the limitations of existing statistical models in analyzing and interpreting highly skewed miRNA-seq raw read count data that can range from zero to millions. A heavy-tailed model using discrete stable distributions is proposed as a novel approach to better capture the heterogeneity and extreme values commonly observed in miRNA-seq data. Additionally, the parameters of the ...

Low intervention engagement is common in mental health and health behavior change interventions, but research on engagement is scattered, and heterogeneity in the definition and measurement of engagement is large. To aid future engagement research, we conducted an integrative review in which we 1) discuss definitions of engagement, 2) highlight four complementary models of engagement, and 3) ...

Bakgrunn: I Europa øker andelen proteseoperasjoner. Samtidig går det fysiske aktivitetsnivået i befolkningen ned. Andelen med overvekt og fedme øker. Et transeuropeisk prosjekt for å promotere fysisk aktivitet hos pasienter etter proteseoperasjon ble derfor gjennomført. Denne artikkelen baseres på en delstudie som har kartlagt faktorer som bidrar å forklare holdninger til fysisk aktivitet hos pasienter ...

This study presents the perspective of an international group of experts, providing an overview of existing models and policies and guidance to facilitate a proper and sustainable implementation of C-reactive protein point-of-care testing (CRP POCT) to support antibiotic prescribing decisions for respiratory tract infections (RTIs) with the aim to tackle antimicrobial resistance (AMR). AMR threatens ...

Background: Coronavirus Disease 2019 (COVID-19), a highly contagious respiratory illnesses, has globally impacted mental health. This study aims to investigate the association between intolerance of uncertainty and depressive symptoms during the pandemic in New York, USA, considering COVID-19-related worries as modifiers and mediators.<p> <p>Method: 1227 participants from three ongoing cohort ...

Objective: Acupuncture, acknowledged as a potent non-pharmacological therapy, is frequently employed to alleviate pain. Despite its widespread use, there has been a lack of overarching bibliometric analysis of clinical research on acupuncture analgesia. We aimed to summarize current patterns, hotspots, and development trends in this field through bibliometric analysis.<p> <p>Methods: This study ...