Institutt for samfunnsmedisin: Recent submissions

Now showing items 21-40 of 1877

    • Multiple Chemical Sensitivity: Catching up to what kind of science? 

      Pitron, Victor; Köteles, Ferenc Gabor; Nordin, Steven; Haanes, Jan Vilis; Hillert, Lena; Léger, Damien; Lemogne, Cédric; Szemerszky, Renata; van Kamp, Irene; van Thriel, Christoph; Witthöft, Michael; Van den Bergh, Omer (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)
      The recent review of Molot et al. (2023) appropriately emphasizes Multiple Chemical Sensitivity (MCS) as a growing health issue and the necessity of dedicated healthcare and medical education. The authors explain MCS mainly as the result of the sensitization of transient receptor potential (TRP) receptors, notably TRPV1 and TRPA1, and oppose this explanation to psychological processes as a causal ...

    • Electrohypersensitivity is always real 

      Pitron, Victor; Haanes, Jan Vilis; Hillert, Lena; Köteles, Ferenc Gabor; Leger, Damien; Lemogne, Cedric; Nordin, Steven; Szemerszky, Renata; van Kamp, Iren; van Triel, Christoph; Witthöft, Michael; Van den Bergh, Omer (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-01)
      Given the rapid increase of electromagnetic fields in our environment, the recent review paper by Belpomme and Irigaray (2022) (https://doi.org/10.1016/j.envres.2022.113374) is timely in trying to integrate and discuss the available evidence to understand electrohypersensitivity (EHS), also called idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF) or symptoms associated ...

    • Investigating the effects of the ketone body ß-hydroxybutyrate and the anti-cancer compound MHP88 on glioblastoma multiforme cells in vitro 

      Sønslien, Anna Øien (Mastergradsoppgave; Master thesis, 2021-05-16)
      Introduction: Glioblastoma multiforme (GBM) is the most aggressive human brain tumor with a mean survival of 15 months. It is therefore necessary to explore new treatment strategies, and to study how different hallmarks of cancer can be utilized in this regard. The marine natural product mimic MHP88 can attack the cancer cells’ ability to evade immune destruction by inducing immunogenic cell death ...

    • Recommendations for the development, implementation, and reporting of control interventions in efficacy and mechanistic trials of physical, psychological, and self-management therapies: the CoPPS Statement 

      Hohenschurz-Schmidt, David; Vase, Lene; Scott, Whitney; Annoni, Marco; Ajayi, Oluwafemi K; Barth, Jürgen; Bennell, Kim; Berna, Chantal; Bialosky, Joel; Braithwaite, Felicity; Finnerup, Nanna B.; de C Williams, Amanda C; carlino, elisa; Ceritelli, Francesco; Chaibi, Aleksander; Cherkin, Dan; Colloca, Luana; Cote, Pierre; Darnall, Beth D; Evans, Roni; Fabre, Laurent; Faria, Vanda; French, Simon D; Gerger, Heike; Häuser, Winfried; Hinman, Rana S.; Ho, Dien; Janssens, Thomas; Jensen, Karin; Johnston, Chris; Juhl Lunde, Sigrid; Keefe, Francis; Kerns, Robert D; Koechlin, Helen; Kongsted, Alice; Michener, Lori A; Moerman, Daniel E; Musial, Frauke; Newell, David; Nicholas, Michael; Palermo, Tonya M; Palermo, Sara; Peerdeman, Kaya J.; Pogatzky-Zahn, Esther M; Puhl, Aaron A; Roberts, Lisa; Rossettini, Giacomo; Tomczak Matthiesen, Susan; Underwood, Martin; Vaucher, Paul; Vollert, Jan; Wartolowska, Karolina; Weimer, Katja; Werner, Christoph Patrick; Rice, Andrew S C; Draper-Rodi, Jerry (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-25)
      Control interventions (often called “sham,” “placebo,” or “attention controls”) are essential for studying the efficacy or mechanism of physical, psychological, and self-management interventions in clinical trials. This article presents core recommendations for designing, conducting, and reporting control interventions to establish a quality standard in non-pharmacological intervention research. A ...

    • Automated calibration for stability selection in penalised regression and graphical models 

      Bodinier, Barbara; Filippi, Sarah; Nøst, Therese Haugdahl; Chiquet, Julien; Chadeau-Hyam, Marc (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-13)
      Stability selection represents an attractive approach to identify sparse sets of features jointly associated with an outcome in high-dimensional contexts. We introduce an automated calibration procedure via maximisation of an in-house stability score and accommodating a priori-known block structure (e.g. multi-OMIC) data. It applies to [Least Absolute Shrinkage Selection Operator (LASSO)] penalised ...

    • Pragmatic randomized controlled trial comparing a complex telemedicine-based intervention with usual care in patients with chronic conditions 

      Sten-Gahmberg, Susanna; Sten-gahmberg, Susanna; Pedersen, Kine; Harsheim, Ingrid gaarder; Løyland, Hanna Isabel; Snilsberg, Øyvind; Iversen, Tor; Godager, Geir; Sæther, Erik Magnus; Abelsen, Birgit (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-31)
      This study evaluates a complex telemedicine-based intervention targeting patients with chronic health problems. Computer tablets and home telemonitoring devices are used by patients to report point-of-care measurements, e.g., blood pressure, blood glucose or oxygen saturation, and to answer health-related questions at a follow-up center. We designed a pragmatic randomized controlled trial to compare ...

    • Evaluering av pilotprosjekt med primærhelseteam og alternative finansieringsordninger. Statusrapport 2 

      Abelsen, Birgit; Gaski, Margrete; Godager, Geir; Iversen, Tor; Løyland, Hanna Isabel; Pedersen, Kine; Snilsberg, Øyvind (Research report; Forskningsrapport, 2019-12-02)
      I evalueringens andre statusrapport har vi undersøkt hvordan arbeidet med primærhelseteam (PHT) foregår og fungerer ved alle legekontorene som inngår i forsøket. Arbeidet med PHT er godt i gang ved alle legekontorene, selv om oppstarten for mange har tatt tid. Antallet pasienter som omfattes av PHT er økende. Det er stor variasjon i organisering av teamarbeidet på legekontorene. Sykepleiernes innsats ...

    • Evaluering av pilotprosjekt med primærhelseteam og alternative finansieringsordninger: Sluttrapport 2018 – 2023 (Statusrapport VI) 

      Aandahl, Emilie; Abelsen, Birgit; Fosse, Anette; Godager, Geir; Iversen, Tor; Løyland, Hanna Isabel; Pedersen, Kine; Snilsberg, Øyvind; Sæther, Erik Magnus (Research report; Forskningsrapport, 2024)
      Primærhelseteam (PHT) er tverrfaglige team som inkluderer fastlege, sykepleier og helsesekretær. Sentrale målgrupper for PHT er brukere med kronisk sykdom, brukere med psykiske lidelser og rusavhengighet, brukere som omtales som «skrøpelige eldre» og brukere med utviklingshemming og funksjonsnedsettelser, samt «svake etterspørrere». <p> <p>For å finne ut om PHT, med mer systematisk oppfølging av ...

    • Strategies to decrease inequalities in cancer therapeutics, care and prevention: Proceedings on a conference organized by the Pontifical Academy of Sciences and the European Academy of Cancer Sciences, Vatican City, February 23–24, 2023 

      Ringborg, Ulrik; von Braun, Joachim; Celis, Julio; Baumann, Michael; Berns, Anton; Eggermont, Alexander; Heard, Edith; Heitor, Manuel; Chandy, Mammen; Chen, Chien-Jen; Costa, Alberto; De Lorenzo, Francesco; De Robertis, Edward M.; Dubee, Frederick Charles; Ernberg, Ingemar; Gabriel, Mariya; Helland, Åslaug; Henrique, Rui; Jönsson, Bengt; Kallioniemi, Olli; Korbel, Jan; Krause, Mechthild; Lowy, Douglas R.; Michielin, Olivier; Nagy, Peter; Oberst, Simon; Paglia, Vincenzo; Parker, M. Iqbal; Ryan, Kevin; Sawyers, Charles L.; Schüz, Joachim; Silkaitis, Katherine; Solary, Eric; Thomas, David; Turkson, Peter; Weiderpass Vainio, Elisabete; Yang, Huanming (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-22)
      Analyses of inequalities related to prevention and cancer therapeutics/care show disparities between countries with different economic standing, and within countries with high Gross Domestic Product. The development of basic technological and biological research provides clinical and prevention opportunities that make their implementation into healthcare systems more complex, mainly due to the growth ...

    • Feasibility of a new intervention addressing group-based balance and high-intensity training, physical activity, and employment in individuals with multiple sclerosis: a pilot randomized controlled trial 

      Arntzen, Ellen Christin; Braaten, Tonje Bjørndal; Fikke, Hanne Kristin; Normann, Britt (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-08)
      Background and purpose: Impaired sensorimotor function, reduced physical activity and unemployment are common challenges in persons with multiple sclerosis (pwMS), even when disability is low. CoreDISTparticipation is a new, multidisciplinary intervention delivered across healthcare levels systematically addressing these elements. This study primarily aimed to evaluate the feasibility ...

    • Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival 

      Morra, Anna; Schreurs, Maartje A. C.; Andrulis, Irene L.; Anton-Culver, Hoda; Augustinsson, Annelie; Beckmann, Matthias W.; Behrens, Sabine; Bojesen, Stig E.; Bolla, Manjeet K.; Brauch, Hiltrud; Broeks, Annegien; Buys, Saundra S.; Camp, Nicola J.; Castelao, Jose E.; Cessna, Melissa H.; Chang-Claude, Jenny; Chung, Wendy K.; Sahlberg, Guro Kristine Kleivi; Børresen-Dale, Anne-Lise; Gram, Inger Torhild; Olsen, Karina Standahl; Engebråten, Olav; Naume, Bjørn; Geisler, Jürgen; Grenaker, Grethe Irene; Colonna, Sarah V.; Couch, Fergus J.; Cox, Angela; Cross, Simon S.; Czene, Kamila; Daly, Mary B.; Dennis, Joe; Devilee, Peter; Dörk, Thilo; Dunning, Alison M.; Dwek, Miriam; Easton, Douglas F.; Eccles, Diana M.; Eriksson, Mikael; Evans, D. Gareth; Fasching, Peter A.; Fehm, Tanja N.; Figueroa, Jonine D.; Flyger, Henrik; Gabrielson, Marike; Gago-Dominguez, Manuela; García-Closas, Montserrat; García-Sáenz, José A.; Genkinger, Jeanine; Grassmann, Felix; Gündert, Melanie; Hahnen, Eric; Haiman, Christopher A.; Hamann, Ute; Harrington, Patricia A.; Hartikainen, Jaana M.; Hoppe, Reiner; Hopper, John L.; Houlston, Richard S.; Howell, Anthony; Jakubowska, Anna; Janni, Wolfgang; Jernström, Helena; John, Esther M.; Johnson, Nichola; Jones, Michael E.; Kristensen, Vessela N.; Kurian, Allison W.; Lambrechts, Diether; Le Marchand, Loic; Lindblom, Annika; Lubiński, Jan; Lux, Michael P.; Mannermaa, Arto; Mavroudis, Dimitrios; Mulligan, Anna Marie; Muranen, Taru A.; Nevanlinna, Heli; Nevelsteen, Ines; Neven, Patrick; Newman, William G.; Obi, Nadia; Offit, Kenneth; Olshan, Andrew F.; Park-Simon, Tjoung-Won; Patel, Alpa V.; Peterlongo, Paolo; Phillips, Kelly-Anne; Plaseska-Karanfilska, Dijana; Polley, Eric C.; Presneau, Nadege; Pylkäs, Katri; Rack, Brigitte; Radice, Paolo; Rashid, Muhammad U.; Rhenius, Valerie; Robson, Mark; Romero, Atocha; Saloustros, Emmanouil; Sawyer, Elinor J.; Schmutzler, Rita K.; Schuetze, Sabine; Scott, Christopher; Shah, Mitul; Smichkoska, Snezhana; Southey, Melissa C.; Tapper, William J.; Teras, Lauren R.; Tollenaar, Rob A. E. M.; Tomczyk, Katarzyna; Tomlinson, Ian; Troester, Melissa A.; Vachon, Celine M.; van Veen, Elke M.; Wang, Qin; Wendt, Camilla; Wildiers, Hans; Winqvist, Robert; Ziogas, Argyrios; Hall, Per; Pharoah, Paul D. P.; Adank, Muriel A.; Hollestelle, Antoinette; Schmidt, Marjanka K.; Hooning, Maartje J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-03)
      Background - Breast cancer (BC) patients with a germline CHEK2 c.1100delC variant have an increased risk of contralateral BC (CBC) and worse BC-specific survival (BCSS) compared to non-carriers.<p> <p>Aim - To assessed the associations of CHEK2 c.1100delC, radiotherapy, and systemic treatment with CBC risk and BCSS.<p> <p>Methods - Analyses were based on 82,701 women diagnosed with a first ...

    • Exploring Online Health Information Seeking Behaviour (OHISB) among young adults: A scoping review protocol 

      Bratland, Kristine Moksnes; Wien, Charlotte; Sandanger, Torkjel Manning (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-30)
      <p><i>Introduction</i> In recent years, information technology and social media have experienced unprecedented growth, particularly in the Nordic countries. However, there is a noticeable lack of comprehensive understanding regarding the latest research findings on online health information seeking behaviour (OHISB) among young adults (18 to >30). There is a need to conduct an updated review to ...

    • Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial. 

      Roaldsen, Melinda Berg; Eltoft, Agnethe; Wilsgaard, Tom; Christensen, Hanne; Engelter, Stefan T.; Indredavik, Bent; Jatužis, Dalius; Karelis, Guntis; Kõrv, Janika; Lundström, Erik; Petersson, Jesper; Putaala, Jukka; Søyland, Mary-Helen; Tveiten, Arnstein; Bivard, Andrew; Johnsen, Stein Harald; Mazya, Michael; Werring, David J; Wu, Teddy Y; de Marchis, Gian Marco; Robinson, Thompson G; Mathiesen, Ellisiv B (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-19)
      Background - Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often scarce. We aimed to determine whether thrombolytic treatment with intravenous tenecteplase given within 4·5 h of awakening improves functional ...

    • Data driven or data informed? How general practitioners use data to evaluate their own and colleagues’ clinical work in clusters 

      Haase, Christoffer Bjerre; Bearman, Margaret; Brodersen, John; Risør, Torsten; Hoeyer, Klaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-29)
      In contemporary policy discourses, data are presented as key assets for improving health-care quality: policymakers want health care to become ‘data driven’. In this article, we focus on a particular example of this ambition, namely a new Danish national quality development program for general practitioners (GPs) where doctors are placed in so-called ‘clusters’. In these clusters, GPs are obliged ...

    • Recognition of COVID-19 with occupational origin: a comparison between European countries 

      Nys, Evelien; Pauwels, Sara; Ádám, Balázs; Amaro, João; Athanasiou, Athanasios; Bashkin, Osnat; Bric, Tatjana Kofol; Bulat, Petar; Caglayan, Cigdem; Canu, Irina Guseva; Cebanu, Serghei; Charbotel, Barbara; Cirule, Jolanta; Curti, Stefania; Davidovitch, Nadav; Dopelt, Keren; Fikfak, Metoda Dodic; Frilander, Heikki; Gustavsson, Per; Höper, Anje Christina; Sibel, Kiran; Kogevinas, Manolis; Kudász, Ferenc; Kolstad, Henrik A.; Lazarevic, Sanja Brekalo; Macan, Jelena; Majery, Nicole; Marinaccio, Alessandro; Mates, Dana; Mattioli, Stefano; McElvenny, Damien Martin; Mediouni, Zakia; Mehlum, Ingrid Sivesind; Merisalu, Eda; Mijakoski, Dragan; Nena, Evangelia; Noone, Peter; Otelea, Marina Ruxandra; Pelclova, Daniela; Pranjic, Nurka; Rosso, Mark; Serra, Consol; Rushton, Lesley; Sandal, Abdulsamet; Schernhammer, Eva S.; Stoleski, Sasho; Turner, Michelle C.; van der Molen, Henk F.; Varga, Marek; Walusiak-Skorupa, Jolanta; Straif, Kurt; Godderis, Lode (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-20)
      Objectives -This study aims to present an overview of the formal recognition of COVID-19 as occupational disease (OD) or injury (OI) across Europe.<p> <p>Methods - A COVID-19 questionnaire was designed by a task group within COST-funded OMEGA-NET and sent to occupational health experts of 37 countries in WHO European region, with a last update in April 2022.<p> <p>Results - The questionnaire ...

    • Increased expression of individual genes in whole blood is associated with late-stage lung cancer at and close to diagnosis 

      Urbarova, Ilona Halva; Skogholt, Anne Heidi; Sun, Yi-Qian; Mai, Xiao-Mei; Grønberg, Bjørn Henning; Sandanger, Torkjel Manning; Sætrom, Pål; Nøst, Therese Haugdahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-25)
      Lung cancer (LC) mortality rates are still increasing globally. As survival is linked to stage, there is a need to identify markers for earlier LC diagnosis and individualized treatment. The whole blood transcriptome of LC patients represents a source of potential LC biomarkers. We compared expression of > 60,000 genes in whole blood specimens taken from LC cases at diagnosis (n = 128) and controls ...

    • Primærhelseteam – en mer teambasert fastlegetjeneste 

      Pedersen, Kine; Løyland, Hanna Isabel; Erik Magnus, Sæther; Sten Gahmberg, Susanna; Abelsen, Birgit; Snilsberg, Øyvind; Iversen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-29)
      Primærhelseteam (PHT) er en ny arbeidsform i fastlegetjenesten der lege, sykepleier og helsesekretær jobber sammen i team. Teamet skal tilby gode tjenester og arbeide systematisk med pasientsikkerhet og kvalitetsforbedring. Målgruppene for primærhelseteam er listeinnbyggere med kronisk sykdom, psykiske lidelser og rusavhengighet, skrøpelige eldre, og brukere med utviklingshemming og funksjonsnedsettelser. ...

    • Effekter, gevinster og kostnader ved digital hjemmeoppfølging–en samfunnsøkonomisk analyse basert på et pragmatisk randomisert forsøk 

      Løyland, Hanna Isabel; Kine, Pedersen; Sten Gahmberg, Susanna; Gaarder Harsheim, Ingrid; Sæther, Erik Magnus; Iversen, Tor; Snilsberg, Øyvind; Abelsen, Birgit (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-29)
      Denne studien omhandler en utprøving av digital hjemmeoppfølging i helsetjenesten og omfatter seks lokale prosjekter i kommunene Stad, Bodø, Larvik, Oslo (med bydelene Sagene, Grünerløkka, Gamle Oslo og St. Hanshaugen), Ullensaker (i samarbeid med Gjerdrum) og Kristiansand (i samarbeid med flere Agder-kommuner). Utprøvingen ble gjennomført som en pragmatisk randomisert kontrollert studie. Målgruppen ...

    • Local management of the COVID-19 pandemic in Norway: a longitudinal interview study of municipality chief medical officers 

      Heltveit-Olsen, Silje Rebekka; Lunde, Lene; Brænd, Anja Maria; Spehar, Ivan; Høye, Sigurd; Sundvall, Pär-Daniel; Skoglund, Ingmarie; Fossum, Guro Haugen; Straand, Jørund; Risør, Mette Bech (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-12)
      Objective - To explore the experiences and views of Norwegian Municipality Chief Medical Officers (MCMOs) on preparedness, collaboration, and organization during the COVID-19 pandemic to gain insight into local crisis management of value for future pandemic responses.<p> <p>Design - Longitudinal qualitative interview study. We conducted semi-structured digital interviews with nine MCMOs working ...

    • Vitamin D – a scoping review for Nordic nutrition recommendations 2023 

      Brustad, Magritt; Meyer, Haakon Eduard (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-13)
      Vitamin D is an essential nutrient. Its role in calcium and phosphorous metabolism, and in the development and maintenance of a healthy skeleton is well documented. In addition, there is some evidence for vitamin D decreasing total mortality and cancer mortality modestly, but not cancer incidence. Vitamin D is unique, as both diet and sun induced production in skin are sources to this vitamin. ...