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dc.contributor.authorSolberg, Tore
dc.contributor.authorSørlie, Andreas
dc.contributor.authorSjåvik, Kristin
dc.contributor.authorNygaard, Øystein Petter
dc.contributor.authorIngebrigtsen, Tor
dc.date.accessioned2012-03-14T08:59:17Z
dc.date.available2012-03-14T08:59:17Z
dc.date.issued2011
dc.description.abstractLoss to follow-up may bias the outcome assessments of clinical registries. In this study, we wanted to determine whether outcomes were different in responding and non-responding patients who were included in a clinical spine surgery registry, at two years of follow-up. In addition, we wanted to identify risk factors for failure to respond. 633 patients who were operated for degenerative disorders of the lumbar spine were followed for 2 years using a local clinical spine registry. Those who did not attend the clinic and those who did not answer a postal questionnaire—for whom 2 years of outcome data were missing—and who would be lost to follow-up according to the standard procedures of the registry protocols, were defined as non-respondents. They were traced and interviewed by telephone. Outcome measures were: improvement in health-related quality of life (EQ-5D), leg pain, and back pain; and also general state of health, employment status, and perceived benefits of the operation. We found no statistically significant differences in outcome between respondents (78% of the patients) and nonrespondents (22%). Receipt of postal questionnaires (not being summoned for a follow-up visit) was the strongest risk factor for failure to respond. Forgetfulness appeared to be an important cause. Older patients and those who had complications were more likely to respond. Interpretation A loss to follow-up of 22% would not bias conclusions about overall treatment effects and, importantly, there were no indications of worse outcomes in non-respondents.en
dc.descriptionThis paper is part of Tore Solberg's doctoral thesis, available in Munin at <a href=http://hdl.handle.net/10037/5733>http://hdl.handle.net/10037/5733</a>
dc.identifier.citationActa Orthopaedica 82(2011) nr. 1 s. 56-63en
dc.identifier.cristinIDFRIDAID 829921
dc.identifier.doidoi: 10.3109/17453674.2010.548024
dc.identifier.issn1745-3674
dc.identifier.urihttps://hdl.handle.net/10037/3955
dc.identifier.urnURN:NBN:no-uit_munin_3677
dc.language.isoengen
dc.publisherTaylor & Francisen
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Health service and health administration research: 806en
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Helsetjeneste- og helseadministrasjonsforskning: 806en
dc.titleWould loss to follow-up bias the outcome evaluation of patients operated for degenerative disorders of the lumbar spine?en
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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