Sammendrag Samhandlingsreformen er å anse som oppstarten for elektronisk kommunikasjon i helse- og omsorgssektoren. Denne dialogformen skulle bidra til raskere og sikrere informasjonsutveksling og sømløse pasientforløp. Forskning viser likevel utfordringsområder som bidrar til samhandlingsvansker de ulike tjenestenivåene imellom. Oppgavens problemstilling: «Hvordan skaper elektroniske meldinger ...

Although hypertension is a risk factor for end-stage renal disease, this complication develops in only a minority of hypertensive patients. Whether non-malignant hypertension itself is sufficient to cause reduced glomerular filtration rate (GFR) is unclear. We investigated whether elevated blood pressure (BP) was associated with accelerated GFR decline in the general population. The study ...

Background Questions remain concerning to what extent age and sex may modify the suggested association between psoriasis and the metabolic syndrome in the general population. Objectives To investigate the association between psoriasis and the metabolic syndrome within a large population-based cohort by age and sex.<p> <p>Methods A cross-sectional study including 10 521 participants aged 30–79 ...

Venous thromboembolism (VTE) is a common, multi-causal disease with potentially serious short- and long-term complications. In clinical practice, there is a need for improved plasma biomarker-based tools for VTE diagnosis and risk prediction. Here we show, using proteomics profiling to screen plasma from patients with suspected acute VTE, and several case-control studies for VTE, how Complement ...

<p><i>Background</i> D-dimer, a global biomarker for activation of the coagulation and fibrinolysis systems, is useful in assessing individual risk of venous thromboembolism (VTE) recurrence. However, there is limited information on the association between D-dimer and risk of a first lifetime VTE event. <p><i>Objectives</i> To investigate the association between plasma D-dimer levels and risk of ...

Over-the-counter (OTC) medications are products that have been made easily accessible to allow patients to treat common ailments without a prescription and the cost of a doctor’s visit. These medications are generally considered safe; however, there is still a potential for these medications to lead to adverse health outcomes. Older adults (ages 50+) are especially susceptible to these adverse health ...

Cnidarians harbor a variety of small regulatory RNAs that include microRNAs (miRNAs) and PIWI-interacting RNAs (piRNAs), but detailed information is limited. Here, we report the identification and expression of novel miRNAs and putative piRNAs, as well as their genomic loci, in the symbiotic sea anemone <i>Anemonia viridis</i>. We generated a draft assembly of the <i>A. viridis</i> genome with ...

Play is an active process by which an individual is intrinsically motivated to explore the self, the environment, and/or interactions with another person. For infants and toddlers, engaging in play is essential to support development across multiple domains. Infants and toddlers with or at risk of motor delays may demonstrate differences in play or challenges with engaging in play activities compared ...

In Norway, as in other countries in the northern hemisphere, an increasing number of people survive after cancer diagnosis and treatment. Earlier studies have shown that life after cancer can be challenging in different ways, which makes it important to gain knowledge about this group to be able to meet their needs in the future. The main objective of this project was to understand the illness ...

Purpose: The purpose of this research was to develop a smartphone based e-medication app for hospitalized patients at the University Hospital of North Norway (UNN). The app was expected to provide an overview of medication that the patient is given during hospitalization. Motivation: E-medication has become widely popular in many countries, and has replaced the paper-based prescription. This ...