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Now showing items 5686-5705 of 10096
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M-ficolin: a valuable biomarker to identify leukaemia from juvenile idiopathic arthritis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)Objective: Distinction on clinical grounds between acute lymphoblastic leukaemia presenting with arthropathy (ALLarthropathy) and juvenile idiopathic arthritis (JIA) is difficult, as the clinical and paraclinical signs of leukaemia may be vague. The primary aim was to examine the use of lectin complement pathway proteins as markers to differentiate ALLarthropathy from JIA. The secondary aims were ... -
MABC-2 i klinisk praksis med undersøkelse av for tidlig fødte barn. Rammer - innhold og relasjoner. En kvalitativ intervjuundersøkelse av foreldres erfaringer
(Master thesis; Mastergradsoppgave, 2014-10-01)M ABC-2 (Movement Assessment Battery for Children) er en standardisert test som brukes ved treårskontroll i henhold til Faglige retningslinjer for oppfølging av for tidlig fødte barn. Hensikten med denne studien er å få innsikt i foreldres erfaringer ved undersøkelse av deres for tidlig fødte barn i 3 årsalder. Problemstillingen det søkes svar på er: Hvordan erfarer og vurderer foreldre til for ... -
Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-19)<i>Objective</i> - We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury.<br><br> <i>Study Design and Setting</i> - We performed logistic regression (LR), lasso regression, and ridge regression with key baseline predictors in the IMPACT-II database (15 studies, <i>n</i> = 11,022). ML algorithms ... -
Machine Learning of Infant Spontaneous Movements for the Early Prediction of Cerebral Palsy: A Multi-Site Cohort Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-18)<i>Background</i>: Early identification of cerebral palsy (CP) during infancy will provide opportunities for early therapies and treatments. The aim of the present study was to present a novel machine-learning model, the Computer-based Infant Movement Assessment (CIMA) model, for clinically feasible early CP prediction based on infant video recordings.<p><p> <i>Methods</i>: The CIMA model was ... -
Machine learning-based immune phenotypes correlate with STK11/KEAP1 co-mutations and prognosis in resectable NSCLC: a sub-study of the TNM-I trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-24)Background - We aim to implement an immune cell score model in routine clinical practice for resected non-small-cell lung cancer (NSCLC) patients (NCT03299478). Molecular and genomic features associated with immune phenotypes in NSCLC have not been explored in detail.<p> <p>Patients and methods - We developed a machine learning (ML)-based model to classify tumors into one of three categories: ... -
Machine-learning-derived heart and brain age are independently associated with cognition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-31)Background and purpose - A heart age biomarker has been developed using deep neural networks applied to electrocardiograms. Whether this biomarker is associated with cognitive function was investigated.<p> <p>Methods - Using 12-lead electrocardiograms, heart age was estimated for a population-based sample (N = 7779, age 40–85 years, 45.3% men). Associations between heart delta age (HDA) and ... -
Macro-kinematic differences between Sprint and Distance cross-country skiing competitions using the classical technique
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-05-17)We compare the macro-kinematics of six elite female cross-country skiers competing in 1.1-km Sprint and 10.5-km Distance classical technique events on consecutive days under similar weather and track conditions. The relative use of double pole (DP), kick-double pole (KDP), diagonal stride (DS), tucking (Tuck) and turning (Turn) subtechniques, plus each technique’s respective velocities, cycle ... -
Macronutrient composition of the diet and prospective weight change in participants of the EPIC-PANACEA study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Background: The effect of the macronutrient composition of the usual diet on long term weight maintenance remains controversial. Methods: 373,803 subjects aged 25–70 years were recruited in 10 European countries (1992–2000) in the PANACEA project of the EPIC cohort. Diet was assessed at baseline using country-specific validated questionnaires and weight and height were measured at baseline and ... -
Macrophage characteristics expressed in monocytes in ICU patients
(Master thesis; Mastergradsoppgave, 2018-06-04)Introduction: Patients presenting in the intensive care unit with severe injury or infections, typically carry a substantial inflammatory cytokine burden. The pathophysiological changes to leukocytes are poorly defined in these patients. This study aims to look at the macrophage-like characteristics of monocytes in patients entering into the ICU with severe inflammation / sepsis. Methods: The study ... -
Macrophage stimulating agent soluble yeast β-1,3/1,6-glucan as a topical treatment of diabetic foot and leg ulcers: A randomized, double blind, placebo-controlled phase II study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Macrophages modulate migration and invasion of human tongue squamous cell carcinoma
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-26)Oral tongue squamous cell carcinoma (OTSCC) has a high mortality rate and the incidence is rising worldwide. Despite advances in treatment, the disease lacks specific prognostic markers and treatment modality. The spreading of OTSCC is dependent on the tumor microenvironment and involves tumor-associated macrophages (TAMs). Although the presence of TAMs is associated with poor prognosis in OTSCC, ... -
Macular Layer Thickness and Effect of BMI, Body Fat, and Traditional Cardiovascular Risk Factors: The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-12)PURPOSE. The purpose of this study was to investigate associations between cardiovascular risk factors and the thickness of retinal nerve fiber layer (RNFL), ganglion cell-inner plexiform layer (GCIPL), and outer retina layers (ORL).<p> <p>METHODS. In this population-based study, we included participants from the Tromsø Study: Tromsø6 (2007 to 2008) and Tromsø7 (2015 to 2016). Persons with ... -
Macular thickness in healthy eyes of adults (N=4508) and relation to sex, age and refraction: The Tromsø Eye Study (2007-08)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-18)Purpose: To provide sex-stratified normative data on retinal thickness and study the relationship with sex, age and refractive status. Methods: Population-based study including 2617 women and 1891 men, aged 38– 87 (mean 61 8) years, without diabetes, glaucoma and retinal diseases, and spherical equivalent refraction (SER) within 6 dioptres. Retinal thickness was measured with optical coherence ... -
Mageleie til ikke-intuberte intensivpasienter. En litteraturstudie med systematisk tilnærming
(Master thesis; Mastergradsoppgave, 2022-05-04)Bakgrunn: COVID-19 er et luftveisvirus som kan føre til ARDS med behov for ventilasjonsstøtte. Mageleie brukes som et behandlingsalternativ til pasienter med ARDS og er påvist å ha god effekt til intuberte pasienter. Etter at COVID-19 pandemien oppstod i 2020 har behovet for forskning på ikke-intuberte ARDS-pasienter behandlet med HFNO og NIV økt. Intensivsykepleiere har en sentral rolle ved å ... -
Maggotterapi
(Master thesis; Mastergradsoppgave, 2008-09-15)Omhandler bruk av maggotterapi i behandlingen av behandlingsresistente sår og inflammerte sår.Gir en oversikt over maggotterapiens prinsipper,virkemåter og muligheter. -
Magnetic resonance imaging for non-invasive measurement of plastic ingestion in marine wildlife
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)Monitoring plastic ingestion by marine wildlife is important for both characterizing the extent of plastic pollution in the environment and understanding its effect on species and ecosystems. Current methods to detect plastic in the digestive system of animals are slow and invasive, such that the number of animals that can be screened is limited. In this article, magnetic resonance imaging (MRI) ... -
Magnetic resonance imaging of pancreatic islets transplantation
(Doctoral thesis; Doktorgradsavhandling, 2012-08-30)Transplanted insulin-producing cells can be safely monitored by magnetic resonance imaging Transplantation of insulin-producing cells can treat patients with diabetes. Unfortunately, the long-term effects of this treatment are poor due to non-survival of the majority of the transplanted cells. In our study, we found that magnetic resonance imaging (MRI) can be safely used to trace survival of the ... -
Magnetic resonance volumetry: prediction of subjective memory complaints and mild cognitive impairment, and associations with genetic and cardiovascular risk factors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-25)<i>Background/Aims</i>: Subjective memory complaints (SMC) are strong predictors of mild cognitive impairment (MCI) and subsequent Alzheimer’s disease. Our aims were to see if fully automated cerebral MR volume measurements could distinguish subjects with SMC and MCI from controls, and if probable parental late-onset Alzheimer’s disease (LOAD), apolipoprotein E ε4 genotype, total plasma homocysteine, ... -
Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-20)Background: Much of the current literature on diet–colorectal cancer (CRC) associations focused on studies of single foods/ nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. <p>Methods: Among 477 312 participants, ... -
Maintaining intravenous volume mitigates hypothermia-induced myocardial dysfunction and accumulation of intracellular Ca2+
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)Previous research exploring pathophysiological mechanisms underlying circulatory collapse after rewarming victims of severe accidental hypothermia has documented post-hypothermic cardiac dysfunction and hypothermia-induced elevation of intracellular Ca<sup>2+</sup> concentration ([Ca<sup>2+</sup>]<sub>i</sub>) in myocardial cells. The aim of the present study was to examine if maintaining euvolaemia ...
