Viser treff 9740-9759 av 10096

    • Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study 

      Schultz, Nina Haagenrud; Søraas, Arne Vasli; Sørvoll, Ingvild Hausberg; Akkøk, Cigdem Ahaein; Vetlesen, Annette; Bhamra, Jagjit Singh; Ahlen, Maria Therese; Holme, Pål Andre; Aamodt, Anne Hege; Skagen, Karolina Ryeng; Skattør, Thor Håkon; Skjelland, Mona; Wiedmann, Markus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)
      Objectives Fatal complications have occurred after vaccination with ChAdOx1 nCoV-19, a vaccine against Covid-19. Vaccine-induced immune thrombotic thrombocytopenia (VITT) with severe outcome is characterized by venous thrombosis, predominantly in cerebral veins, thrombocytopenia and anti-PF4/polyanion antibodies. Prolonged headaches and cutaneous hemorrhages, frequently observed after the ChAdOx1 ...
    • Vaccine Induced Immune Thrombotic Thrombocytopenia Causing a Severe Form of Cerebral Venous Thrombosis With High Fatality Rate: A Case Series 

      Wiedmann, Markus; Skattør, Thor Håkon; Stray-Pedersen, Arne; Romundstad, Luis Georg; Antal, Ellen-Ann; Marthinsen, Pål Bache; Sørvoll, Ingvild Hausberg; Ernstsen, Siw Leiknes; Lund, Christian G.; Holme, Pål Andre; Johansen, Tonje Okkenhaug; Brunborg, Cathrine; Aamodt, Anne Hege; Schultz, Nina Haagenrud; Skagen, Karolina Ryeng; Skjelland, Mona Elisabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-30)
      During a 2-week period, we have encountered five cases presenting with the combination of cerebral venous thrombosis (CVT), intracerebral hemorrhage and thrombocytopenia. A clinical hallmark was the rapid and severe progression of disease in spite of maximum treatment efforts, resulting in fatal outcome in for 4 out of 5 patients. All cases had received ChAdOx1 nCov-19 vaccine 1–2 weeks earlier and ...
    • The Vaginal-PVPA: A Vaginal Mucosa-Mimicking In Vitro Permeation Tool for Evaluation of Mucoadhesive Formulations 

      Falavigna, Margherita; Pattacini, Martina; Wibel, Richard; Sonvico, Fabio; Skalko-Basnet, Natasa; Flaten, Gøril Eide (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-19)
      Drug administration to the vaginal site has gained increasing attention in past decades, highlighting the need for reliable in vitro methods to assess the performance of novel formulations. To optimize formulations destined for the vaginal site, it is important to evaluate the drug retention within the vagina as well as its permeation across the mucosa, particularly in the presence of vaginal fluids. ...
    • Vaksine og screening : ja takk, begge deler! 

      Sørbye, Sveinung Wergeland (Journal article; Tidsskriftartikkel, 2010-01-21)
      - I Norge trenger vi ikke velge mellom HPV-vaksine eller screening. Vi har råd til begge deler.
    • Vaksiner mot humant papillomavirus (HPV). Vurdering av effekt av profylaktiske HPV-vaksiner 

      Nilsen, Ellen M; Alfsen, Cecilie G.; Feiring, Berit; Skjeldestad, Finn Egil; Steen, Rita; Sæterdal, Ingvil von Mehren (Research report; Forskningsrapport, 2007)
      Denne rapporten er første del av et oppdrag fra Nasjonalt folkehelseinstitutt, med fokus på vurdering av effekt og sikkerhet ved bruk av vaksiner mot humant papillomavirus (HPV). Det pågår helseøkonomiske analyser som publiseres i en egen rapport.
    • Valg av antibiotika i Finnmarkssykehuset – fornuft eller følelser? Etterlevelse av nasjonal faglig retningslinje for antibiotikabruk i sykehus 

      Holmgren, Hanne Lovise; Svendsen, Kine Mari (Master thesis; Mastergradsoppgave, 2020-06-23)
      <p>Bakgrunn: I 2013 lanserte Helsedirektoratet nasjonal faglig retningslinje for bruk av antibiotika i sykehus. Denne retningslinjen skal være implementert i norske sykehus, og omhandler valg av empirisk antibiotika, dose, intervall og administrasjon, samt anbefalinger for mikrobiologisk diagnostikk. Hensikten med denne oppgaven er å vurdere etterlevelse av denne retningslinjen, belyst gjennom ...
    • Valg av behandling hos pasienter med Graves sykdom - En kvalitetsundersøkelse ved endokrinologisk seksjon, UNN Tromsø 

      Stormo, Stine Emilie (Master thesis; Mastergradsoppgave, 2018-05-30)
      Bakgrunn: Graves sykdom er en autoimmun tilstand karakterisert av hypertyreose, struma, oftalmopati og pretibial myxødem, ofte med symptomer i form av vektnedgang, hjertebank, varmeintoleranse, søvn- og konsentrasjonsvansker med mer. Insidens av tilstanden ses hyppigst hos kvinner i 30-50 års alder. Medikamentell behandling med tyreostatika anses som førstevalg i behandling av Graves sykdom, men ...
    • Valg av kronemateriale for posteriore konstruksjoner blant offentlige tannleger ved universitetstannklinikker i Norge - En spørreundersøkelsesbasert studie 

      Gustavsen, Mari; Døhl, Emma A. (Master thesis; Mastergradsoppgave, 2020-05-18)
      Hensikten med masteroppgaven er å få et innblikk i hvilke faktorer som påvirker valg av kronemateriale blant tannleger ansatt på offentlige klinikker, tilknyttet Universitet i Tromsø. Oppgaven fokuserer på posteriore, single kroner, og hva tannlegene vektlegger når de velger materiale. Når tannleger velger kronematerial, så kan flere faktorer påvirke valget, for eksempel antall praktiserende år, ...
    • Valgfrihet eller ferie – en studie av 2. års valgfriperiode på Profesjonsstudiet i medisin ved Universitetet i Tromsø 

      Martinsen, Finn-Arne (Master thesis; Mastergradsoppgave, 2014-05-25)
      Introduksjon I Norge har man, med bakgrunn i europeiske satsningsområder, utarbeidet en kvalitetsreform og et kvalifikasjonsrammeverk for høyere utdanning. Her står det at det skal legges vekt på valgfrihet i studieløpene. Ved medisinstudiet i Tromsø har man drevet med valgfri undervisning siden dets oppstart i 1973. I 2. års valgfriperiode er det satt av fire uker til arbeid med et selvstendig ...
    • Validating Acute Myocardial Infarction Diagnoses in National Health Registers for Use as Endpoint in Research: The Tromsø Study 

      Varmdal, Torunn; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Njølstad, Inger; Nyrnes, Audhild; Grimsgaard, Sameline; Bønaa, Kaare Harald; Mannsverk, Jan; Løchen, Maja-Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-03)
      <i>Purpose</i>: To assess whether acute myocardial infarction (MI) diagnoses in national health registers are sufficiently correct and complete to replace manual collection of endpoint data for a population-based, epidemiological study.<br><br> <i>Patients and Methods</i>: Using the Tromsø Study Cardiovascular Disease Register for 2013– 2014 as gold standard, we calculated correctness (defined ...
    • Validating Biobehavioral Technologies for Use in Clinical Psychiatry 

      Cohen, Alex S.; Cox, Christopher R.; Tucker, Raymond P.; Mitchell, Kyle R.; Schwartz, Elana K.; Le, Thanh P.; Foltz, Peter W.; Holmlund, Terje Bektesevic; Elvevåg, Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-11)
      The last decade has witnessed the development of sophisticated biobehavioral and genetic, ambulatory, and other measures that promise unprecedented insight into psychiatric disorders. As yet, clinical sciences have struggled with implementing these objective measures and they have yet to move beyond “proof of concept.” In part, this struggle reflects a traditional, and conceptually flawed, application ...
    • Validating the Eating Disorder Inventory-3 (EDI-3) : A Comparison Between 561 Female Eating Disorders Patients and 878 Females from the General Population 

      Rosenvinge, Jan H; Clausen, Loa; Rokkedal, Kristian; Friborg, Oddgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The Eating Disorder Inventory (EDI) is used worldwide in research and clinical work. The 3rd version (EDI-3) has been used in recent research, yet without any independent testing of its psychometric properties. The aim of the present study was twofold: 1) to establish national norms and to compare them with the US and international norms, and 2) to examine the factor structure, the internal consistency, ...
    • Validation of a graded prognostic model in patients with brain metastases treated with whole-brain radiotherapy instead of radiosurgery 

      Nieder, Carsten; Mannsåker, Bård; Yobuta, Rosalba (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05)
      Background/Aim: The aim of this study was to analyze the survival predictions obtained from a recent graded prognostic model developed and validated in Japan.<p><p> Patients and Methods: This was a retrospective single-institution analysis of 249 patients, managed with whole-brain radiotherapy for brain metastases. The sum of scores was calculated as in the Japanese study. The following parameters ...
    • Validation of a Norwegian Translation of the Acceptance of Modern Myths About Sexual Aggression Scale in a Norwegian Student Population 

      Jakobsen, Igor (Master thesis; Mastergradsoppgave, 2016-05-02)
      There is a high incidence of rape and party related rape in Norway. To combat this, it has been proposed to aim interventions at rape myth acceptance, since it has been shown to affect rape proclivity. This study examined how a Norwegian translation of the Acceptance of Modern Myths About Sexual Aggression scale performs in a Norwegian student population. 109 male and female participants completed ...
    • Validation of a prediction model for post-chemotherapy fibrosis in nonseminoma patients 

      Gerdtsson, Axel; Torisson, Gustav; Thor, Anna; Grenabo Bergdahl, Anna; Almås, Bjarte; Håkansson, Ulf; Törnblom, Magnus; Negaard, Helene Francisca Stigter; Glimelius, Ingrid; Halvorsen, Dag; Karlsdottir, Åsa; Haugnes, Hege Sagstuen; Larsen, Signe Melsen; Holmberg, Göran; Wahlqvist, Rolf; Tandstad, Torgrim; Cohn-Cedermark, Gabriella; Ståhl, Olof; Kjellman, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-02)
      Objective - To validate Vergouwe's prediction model using the Swedish and Norwegian Testicular Cancer Group (SWENOTECA) RETROP database and to define its clinical utility.<p> <p>Materials and methods - Vergouwe's prediction model for benign histopathology in post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) uses the following variables: presence of teratoma in orchiectomy specimen; ...
    • Validation of diagnostic utility of fasting plasma glucose and HbA1c in stable renal transplant recipients one year after transplantation 

      Ussif, Mohammed Al-Amin; Åsberg, Anders; Strøm Halden, Thea Anine; Nordheim, Espen; Hartmann, Anders; Jenssen, Trond Geir (Journal article; Peer reviewed, 2019-01-10)
      <b>Background</b><br> The use of HbA1c ≥6.5% for diagnosis of diabetes has been challenged for post-transplantation diabetes mellitus (PTDM) also known as new onset diabetes after transplantation (NODAT) due to a low sensitivity early after renal transplantation. PTDM diagnosed with an oral glucose tolerance test (OGTT) is highly predictable for long-term patient mortality. HbA1c was introduced for ...
    • Validation of eGFR for Detecting Associations Between Serum Protein Biomarkers and Subsequent GFR Decline 

      Enoksen, Inger Therese Tønsberg; Rinde, Nikoline Balteskard; Svistounov, Dmitri; Norvik, Jon Viljar Porserud; Solbu, Marit Dahl; Eriksen, Bjørn Odvar; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08)
      Significance Statement - eGFR from creatinine, cystatin C, or both has been primarily used in search of biomarkers for GFR decline. Whether the relationships between biomarkers and eGFR decline are similar to associations with measured GFR (mGFR) decline has not been investigated. This study revealed that some biomarkers showed statistically significant different associations with eGFR decline ...
    • Validation of forearm fracture diagnoses in administrative patient registers 

      Omsland, Tone Kristin; Solberg, Lene Bergendal; Bjørnerem, Åshild Marit; Borgen, Tove Tveitan; Andreasen, Camilla; Wisløff, Torbjørn; Hagen, Gunhild; Basso, Trude; Gjertsen, Jan-Erik; Apalset, Ellen Margrete; Figved, Wender; Stutzer, Jens-Meinhard; Nissen, Frida Igland; Hansen, Ann Kristin; Joakimsen, Ragnar Martin; Figari, Elisa; Peel, Geoffrey; Rashid, Ali A.; Khoshkhabari, Jashar; Eriksen, Erik Fink; Nordsletten, Lars; Frihagen, Frede; Dahl, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-24)
      Summary The validity of forearm fracture diagnoses recorded in fve Norwegian hospitals was investigated using image reports and medical records as gold standard. A relatively high completeness and correctness of the diagnoses was found. Algorithms used to defne forearm fractures in administrative data should depend on study purpose.<p> <p>Purpose In Norway, forearm fractures are routinely recorded ...
    • Validation of forearm fracture diagnoses in administrative patient registers 

      Omsland, Tone Kristin; Solberg, Lene Bergendal; Bjørnerem, Åshild Marit; Borgen, Tove Tveitan; Andreasen, Camilla; Wisløff, Torbjørn; Hagen, Gunhild; Basso, Trude; Gjertsen, Jan-Erik; Apalset, Ellen Margrete; Figved, Wender; Stutzer, Jens-Meinhard; Nissen, Frida Igland; Hansen, Ann Kristin; Joakimsen, Ragnar Martin; Figari, Elisa; Peel, Geoffrey; Rashid, Ali A.; Khoshkhabari, Jashar; Eriksen, Erik Fink; Nordsletten, Lars; Frihagen, Frede; Dahl, Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-24)
      Summary The validity of forearm fracture diagnoses recorded in fve Norwegian hospitals was investigated using image reports and medical records as gold standard. A relatively high completeness and correctness of the diagnoses was found. Algorithms used to define forearm fractures in administrative data should depend on study purpose.<p> <p>Purpose In Norway, forearm fractures are routinely recorded ...
    • Validation of repeated self-reported n-3 PUFA intake using serum phospholipid fatty acids as a biomarker in breast cancer patients during treatment 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 

      Brunvoll, Sonja Hjellegjerde; Thune, Inger; Frydenberg, Hanne; Flote, Vidar Gordon; Bertheussen, Gro Falkener; Schlichting, Ellen; Bjerve, Kristian S; Hjartåker, Anette (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      <p><i>Background</i>: The role of n-3 polyunsaturated fatty acids (PUFAs) in breast cancer is not clear and under debate. To explore this relationship it is important to have proper validated dietary assessment methods for measuring the intake of n-3 PUFAs. The aim of the current study is to validate two different methods used to assess the intake of selected n-3 PUFAs as well as food sources of ...