Now showing items 1095-1114 of 10152

    • The burden of colon cancer attributable to modifiable factors—The Norwegian Women and Cancer Study 

      Lukic, Marko; Licaj, Idlir; Laaksonen, Maarit A.; Weiderpass, Elisabete; Borch, Kristin Benjaminsen; Rylander, Charlotta (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)
      Colon cancer is the second most frequently diagnosed cancer in women in Norway, where incidence rates of colon cancer increased 3-fold between 1955 and 2014, for unknown reasons. We aimed to assess the burden of colon cancer attributable to modifiable risk factors in Norwegian women using the data from the Norwegian Women and Cancer (NOWAC) study. Self-reported information from 35 525 women from the ...
    • Burden of hip fracture using disability-adjusted life-years: a pooled analysis of prospective cohorts in the CHANCES consortium 

      Papadimitriou, Nikos; Tsilidis, Konstantinos K.; Orfanos, Philippos; Benetou, Vassiliki; Ntzani, Evangelia E.; Soerjomataram, Isabelle; Künn-Nelen, Annemarie; Pettersson-Kymmer, Ulrika; Eriksson, Sture; Brenner, Hermann; Schöttker, Ben; Saum, Kai-Uwe; Holleczek, Bernd; Grodstein, Francine D.; Feskanich, Diane; Orsini, Nicola; Wolk, Alicja; Bellavia, Andrea; Wilsgaard, Tom; Jørgensen, Lone; Boffetta, Paolo; Trichopoulos, Dimitrios; Trichopoulou, Antonia (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-11)
      <p><i>Background</i>: No studies have estimated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-up cohort data. We aimed to quantify the burden of disease due to incident hip fracture using DALYs in prospective cohorts in the CHANCES consortium, and to calculate population attributable fractions based on DALYs for specific risk factors.</p> <p><i>Methods</i>: ...
    • The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level: Results From the Global Burden of Disease Study 2015 

      Akinyemiju, Tomi; Abera, Semaw; Ahmed, Muktar; Vollset, Stein Emil; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-05)
      Liver cancer is among the leading causes of cancer deaths in many countries. Causes of liver cancer differ widely among populations. Our results show that most cases of liver cancer can be prevented through vaccination, antiviral treatment, safe blood transfusion and injection practices, as well as interventions to reduce excessive alcohol use. In line with the Sustainable Development Goals, the ...
    • Burden, antibiotic resistance, and clonality of shigella spp. Implicated in community-acquired acute diarrhoea in Lilongwe, Malawi 

      Phiri, Abel F.N.D.; Abia, Akebe Luther King; Amoako, Daniel Gyamfi; Mkakosya, Rajab; Sundsfjord, Arnfinn; Essack, Sabiha; Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-28)
      Although numerous studies have investigated diarrhoea aetiology in many sub-Saharan African countries, recent data on <i>Shigella</i> species’ involvement in community-acquired acute diarrhoea (CA-AD) in Malawi are scarce. This study investigated the incidence, antibiotic susceptibility profile, genotypic characteristics, and clonal relationships of <i>Shigella flexneri</i> among 243 patients ...
    • Buried alive: A qualitative study of avalanche survivors’ learning experience after an avalanche accident 

      Kristensen, Thea; Hielm, Iselin (Mastergradsoppgave; Master thesis, 2023-02-14)
      With the growing appeal of backcountry skiing, there has been a rise in interest and research into avalanches and people's embedded role in these. Avalanche terrain presents a complex learning environment as the feedback one receives from the terrain can be both misleading and non-existent. Previous accident studies in particular along with avalanche literature at large has been conducted using ...
    • Burnout and Engagement at the Northernmost University in the World 

      Kaiser, Sabine; Richardsen, Astrid Marie; Martinussen, Monica (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-12)
      Few studies have looked at the relationship of job characteristics and worker well-being among Norwegian academics. The main purpose of this study was to examine the relationship between job demands, job resources, burnout, and engagement among Norwegian university staff. In total, 236 staff from one university in Norway answered the questionnaire. Hierarchical multiple regression analyses identified ...
    • The butterfly design as an alternative to the "double-A" bilateral flaps for the treatment of sacral defects 

      Weum, Sven Magne; De Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-04)
      Letter to the Editor
    • Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes 

      Wibroe, Peter Popp; Anselmo, Aaron C; Nilsson, Per; Sarode, Apoorva; Gupta, Vivek; Urbanics, Rudolf; Szebeni, Janos; Hunter, Alan Christy; Mitragotri, Samir; Mollnes, Tom Eirik; Moghimi, Seyed Moein (Journal article; Manuskript; Tidsskriftartikkel; Peer reviewed; Preprint, 2017-04-10)
      Intravenously injected nanopharmaceuticals, including PEGylated nanoparticles, induce adverse cardiopulmonary reactions in sensitive human subjects, and these reactions are highly reproducible in pigs. Although the underlying mechanisms are poorly understood, roles for both the complement system and reactive macrophages have been implicated. Here, we show the dominance and importance of robust ...
    • Bystander first aid in trauma – prevalence and quality: a prospective observational study 

      Bakke, Håkon Kvåle; Steinvik, Tine; Eidissen, Silje-Iren; Gilbert, Mads; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-06-19)
      Background: Bystander first aid and basic life support can likely improve victim survival in trauma. In contrast to bystander first aid and out-of-hospital cardiac arrest, little is known about the role of bystanders in trauma response. Our aim was to determine how frequently first aid is given to trauma victims by bystanders, the quality of this aid, the professional background of first-aid ...
    • Bør rusavhengige kvinner tilbys kjønnsspesifikk behandling? En kvalitativ studie av helsepersonells erfaringer med behandlingstilbudet for kvinnelige rusmiddelavhengige 

      Ekanger, Silje Margrethe; Straume, Randi (Master thesis; Mastergradsoppgave, 2022-12-13)
      Denne hovedoppgaven er en kvalitativ, semi-strukturert intervjustudie av 8 behandleres erfaringer med behandlingstilbudet til rusmiddelavhengige kvinner og menn. Hovedfokus var hvordan de opplever at rusmiddelavhengige kvinner har det i døgnbehandling for rusmiddelavhengighet. Underveis i studien ble vi klar over at rusmiddelavhengige er en svært heterogen pasientgruppe, med mange og sammensatte ...
    • Bør vi spise mer fisk – eller mindre? 

      Bolann, Bjørn; Huber, Sandra; Averina, Maria; Eggesbø, Merete Åse; Hokstad, Ingrid; Brox, Jan; Ørebech, Peter Th; Monsen, Anne-Lise Bjørke (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-22)
    • C-reactive protein and its associations with сardiometabolic risk factors and echocardiographic indicators of heart failure: results of “Know your heart” study in Arkhangelsk 

      Mirolyubova, Olga A.; Kudryavtsev, Alexander V.; Semchyugova, Elvira; Malyutina, Sofia; Ryabikov, Andrey (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09)
      <p><i>Цель - </i>Оценка связи высокочувствительного С-реактивного белка (вчСРБ) с кардиометаболическими и эхокардиографическими (ЭхоКГ) индикаторами сердечной недостаточности (СН) среди взрослого населения Северного региона России. <p><i>Материал и методы - </i>Поперечное исследование «Узнай свое сердце» проведено в 2015–2017 гг. на случайной выборке общего населения г. Архангельска в возрасте 35–69 ...
    • C-reactive protein and other circulating biomarkers in carotid atherosclerosis and cardiovascular disease. The Tromsø Study 1994-2013 

      Eltoft, Agnethe (Doctoral thesis; Doktorgradsavhandling, 2018-11-07)
      Hjerte- og karsykdom er ledende årsak til død og sykelighet på verdensbasis. I Norge er det årlig ca. 13 000 hjerteinfarkt og 12 000 hjerneslag. Til tross for at den forebyggende og akuttmedisinske behandlingen er betydelig forbedret i løpet av de siste 30 år, forventes en fortsatt økning i hjerte- og karsykdommer på verdensbasis. De tradisjonelle risikofaktorene (alder, kjønn, blodtrykk, kolesterol, ...
    • C-reactive protein and risk of venous thromboembolism: Results from a population-based case-crossover study 

      Grimnes, Gro; Isaksen, Trond; Tichelaar, Ynse Ieuwe Gerardus Vladimir; Brox, Jan; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-19)
      Long-term, low-grade inflammation does not seem to be a risk factor for venous thromboembolism. The impact of acute inflammation, regardless of cause, on risk of venous thromboembolism is scarcely studied. We aimed to investigate the impact of acute inflammation, assessed by C-reactive protein, on short-term risk of venous thromboembolism. We conducted a case-crossover study of patients with venous ...
    • C-Reactive Protein and TGF-α Predict Psychological Distress at Two Years of Follow-Up in Healthy Adolescent Boys: The Fit Futures Study 

      Linkas, Jonas; Ahmed, Luai A.; Csifcsak, Gabor; Emaus, Nina; Furberg, Anne-Sofie; Grimnes, Guri; Pettersen, Gunn; Rognmo, Kamilla; Christoffersen, Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-11)
      Objective: The scarcity of research on associations between inflammatory markers and symptoms of depression and anxiety during adolescence has yielded inconsistent results. Further, not all studies have controlled for potential confounders. We explored the associations between baseline inflammatory markers and psychological distress including moderators at follow-up in a Norwegian adolescent population ...
    • C-reactive protein levels and depression in older and younger adults - A study of 19,947 individuals. The Tromsø study 

      Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Lapid, Maria I.; Grønli, Ole Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-17)
      In recent years, a connection between depression and inflammation has been established, with a range of immunological changes, both cellular and humoral, presenting during depressive states (Beydoun et al., 2016; Haapakoski et al., 2015; Wium-Andersen et al., 2013). Furthermore, there seems to be a dose-response relationship between depression and inflammation, in the sense that the more severe the ...
    • C-reactive protein point-of-care testing and antibiotic prescribing for acute respiratory tract infections in rural primary health centres of North Ethiopia: A cross-sectional study 

      Yebyo, Henock; Medhanyie, Araya Abrha; Spigt, Marcus; Hopstaken, Rogier (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-14)
      Unjustified antibiotic prescribing for acute upper respiratory infections (URTIs) is probably more common in poor-resource settings where physicians are scarce. Introducing C-reactive protein (CRP) point-of-care testing in such settings could reduce the misuse of antibiotics, which could avert antibiotic resistance. However, information useful for the applicability of CRP test in resource-limited ...
    • C-reactive protein point-of-care testing and complementary strategies to improve antibiotic stewardship in children with acute respiratory infections in primary care 

      Staiano, Annamaria; Bjerrum, Lars; Llor, Carl; Melbye, Hasse; Hopstaken, Rogier; Gentile, Ivan; Plate, Andreas; van Hecke, Oliver; Verbakel, Jan Y. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-12)
      This paper provides the perspective of an international group of experts on the role of C-reactive protein (CRP) point-of-care testing (POCT) and complementary strategies such as enhanced communication skills training and delayed prescribing to improve antibiotic stewardship in the primary care of children presenting with an acute illness episode due to an acute respiratory tract infection (ARTI). ...
    • C-reactive protein point-of-care testing for safely reducing antibiotics for acute exacerbations of chronic obstructive pulmonary disease: The PACE RCT 

      Francis, Nick; Gillespie, David; White, Patrick; Bates, Janine; Lowe, Rachel; Sewell, Bernadette; Phillips, Rhiannon; Stanton, Helen; Kirby, Nigel; Wootton, Mandy; Thomas-Jones, Emma; Hood, Kerenza; Llor, Carl; Cals, Jochen; Melbye, Hasse; Naik, Gurudutt; Gal, Micaela; Fitzsimmons, DF; Alam, Mohammed Fasihul; Riga, Evgenia; Cochrane, Ann; Butler, Christopher C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03)
      Background - Most patients presenting with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in primary care are prescribed antibiotics, but these may not be beneficial, and they can cause side effects and increase the risk of subsequent resistant infections. Point-of-care tests (POCTs) could safely reduce inappropriate antibiotic prescribing and antimicrobial resistance.<p> ...
    • C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations 

      Butler, Christopher C; Gillespie, David; White, Patrick; Bates, Janine; lowe, rachel; Thomas-Jones, Emma; Wootton, Mandy; Hood, Kerenza; Phillips, Rhiannon; Melbye, Hasse; Llor, Carl; Cals, Jochen W L; Naik, Gurudutt; Kirby, Nigel; Gal, Micaela; Riga, Evgenia; Francis, Nick A (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-11)
      <i>BACKGROUND</i> - Point-of-care testing of C-reactive protein (CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD).<p><p> <i>METHODS</i> - We performed a multicenter, open-label, randomized, controlled trial involving patients with a diagnosis of COPD in their primary care clinical ...