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Now showing items 13-32 of 10152
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A 4-year follow-up of patients with medication-overuse headache previously included in a randomized multicentre study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)The aim of this study was to evaluate the longterm outcome in 61 patients with medication-overuse headache (MOH) who 4 years previously had been included in a randomized open-label prospective multicentre study. Sixty patients still alive after 4 years were invited to a follow-up investigation. Fifty patients (83%) participated. Sixteen visited a neurologist, 22 were interviewed through telephone, ... -
The 5-HT1E receptor. Receptor structure and ligand interactions.
(Master thesis; Mastergradsoppgave, 2006-12-08)5-HT (5-Hydroxytryptamine; Serotonin) is the neurotransmitter with the highest number of known receptors in humans, and the importance of 5-HT is also reflected in the number of species using 5-HT as a signalling molecule and the number of 5-HT receptors found within each species. 15 human 5-HT receptors have at this date been characterised and classified into seven 5-HT receptor families. Six of ... -
5-type HPV mRNA versus 14-type HPV DNA test: test performance, over-diagnosis and overtreatment in triage of women with minor cervical lesions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-07) -
50 siste reinnleggelser. Analyse av 50 siste reinnleggelser ved Hjertemedisinsk avdeling, UNN Tromsø.
(Master thesis; Mastergradsoppgave, 2018-06-03)Bakgrunn: Reinnleggelse av pasienter er en hyppig brukt kvalitetsindikator i helsevesenet. Reinnleggelser kan være uttrykk for god behandling; for eksempel tett oppfølging av pasienter med kronisk sykdom, såkalt «åpen retur», men kan også være uttrykk for uhensiktsmessige pasientforløp eller kvalitetssvikt. Formålet med studien var å se om man kan identifisere områder for forbedring ved å gjennomgå ... -
6-thioguanin som monoterapautisk behandling av akutt leukemi hos voksne
(Master thesis; Mastergradsoppgave, 2004) -
The 99% accuracy club
(Conference object; Konferansebidrag, 2021)<p>Melanoma Classification - a 10,000$ competition. For the 2020 Melanoma Classification competition hosted by kaggle, 33,126 images were made available for training (of which 2% were melanomas), and an additional 10,982 were used for final ranking of the 3,308 teams who entered the competition with eyes on the 10,000$ prize. The task was simple: provide a probability for melanoma (deadly skin cancer) ... -
The ABC of academic procrastination: Functional analysis of a detrimental habit
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-03)Academic procrastination – habitually delaying work with academic tasks to the extent that the delays become detrimental to performance, wellbeing, and health – represents a substantial personal, systemic, and societal problem. Still, efforts to prevent and reduce it are surprisingly scarce and often offered as treatment regimens rather than preventive efforts. Based on the principles of ... -
ABC-transportørenes kliniske betydning
(Master thesis; Mastergradsoppgave, 2013-06-02)Multi-legemiddelresistens (multidrug resistance, MDR) er resistens mot flere strukturelt uavhengige kjemoterapimidler. Dette er spesielt ett problem for behandling av kreft fordi kreftceller kan danne resistens mot flere midler samtidig. Slik resistens utvikles ved hjelp av flere cellulære mekanismer. Den mest undersøkte og oftest assosierte metoden er via økt uttrykk av ATP-bindende kassett ... -
ABC-transportører
(Mastergradsoppgave; Master thesis, 2009-09-15)ABC (ATP-binding cassette)-transportører er store, evolusjonsmessig høykonserverte membranproteiner som er påvist i alle arter fra prokaryoter til komplekse organismer. ABC-transportørene muliggjør energiavhengig transport av spesifikke substrater gjennom cellemembraner. Blant substratene vi kjenner er lipider, karbohydrater, peptider, vitaminer, steroidhormoner, xenobiotika og medikamenter. ... -
ABCC9-related intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-01)Mutations in genes encoding K<sub>ATP</sub> channel subunits have been reported for pancreatic disorders and Cantú syndrome. Here, we report a syndrome in six patients from two families with a consistent phenotype of mild intellectual disability, similar facies, myopathy, and cerebral white matter hyperintensities, with cardiac systolic dysfunction present in the two oldest patients. Patients are ... -
ABCD before E-verything else—Intensive care nurses' knowledge and experience of pressure injury and moisture-associated skin damage
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-23)Patients in intensive care units are at high risk of developing pressure injuries and moisture-associated skin damages. Prevention and care rely much on intensive care nurses' competency and attitudes. This study explored intensive care nurses' experience, knowledge and bedside practice in prevention and care of pressure injuries and moisture-associated skin damages with a descriptive qualitative ... -
Abdominal aortic aneurysms : diagnosis and epidemiology : the Tromsø Study
(Doctoral thesis; Doktorgradsavhandling, 2005)Abdominal aortic aneurysm (AAA) is a relatively common, potentially life-threatening condition roughly accounting for one percent of all the deaths in the western world. Abdominal aortic aneurysms are usually asymptomatic until rupture. Death from rupture is often sudden and the disease is prone to be misclassified as death from cardiac arrest. Since the introduction of surgical repair of AAA ... -
Abdominal aortic aneurysms, or a relatively large diameter of non-aneurysmal aortas, increase total and cardiovascular mortality: the Tromsø study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010)Background: In a population-based study in Tromsø, Norway, the authors assessed whether an abdominal aortic aneurysm (AAA) or the maximal infrarenal aortic diameter in a non-aneurismal aorta influence total and cardiovascular disease (CVD) mortality. Methods: A total of 6640 men and women, aged 25–84 years, were included in a 10-year mortality follow-up: 345 subjects with a diagnosed AAA and ... -
Abdominal symptoms in general practice: Frequency, cancer suspicions raised, and actions taken by GPs in six European countries. Cohort study with prospective registration of cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06)Background<br> Abdominal symptoms are diagnostically challenging to general practitioners (GPs): although common, they may indicate cancer. In a prospective cohort of patients, we examined abdominal symptom frequency, initial diagnostic suspicion, and actions of GPs in response to abdominal symptoms.<p> Methods<br> Over a 10-day period, 493 GPs in Norway, Denmark, Sweden, Belgium, the Netherlands, ... -
Aberrant salience predicts fluctuations of paranoia two weeks in advance during a 1-year experience sampling method study in people with psychosis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-03)The Experience Sampling Method (ESM) has improved our understanding of psychosis considerably (Myin-Germeys et al., 2018). Not only has ESM shed light on the moment-to-moment variability of psychotic symptoms, it has equally helped to identify micro-level precursor variables that forecast symptom exacerbations a couple of hours in advance. Among others, established ESM-derived precursors are negative ... -
Aberrant uncertainty processing is linked to psychotic-like experiences, autistic traits, and is reflected in pupil dilation during probabilistic learning
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-28)Aberrant belief updating due to misestimation of uncertainty and an increased perception of the world as volatile (i.e., unstable) has been found in autism and psychotic disorders. Pupil dilation tracks events that warrant belief updating, likely refecting the adjustment of neural gain. However, whether subclinical autistic or psychotic symptoms afect this adjustment and how they relate to learning ... -
Aberrant uncertainty processing is linked to psychotic‑like experiences, autistic traits, and is reflected in pupil dilation during probabilistic learning
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-28)Aberrant belief updating due to misestimation of uncertainty and an increased perception of the world as volatile (i.e., unstable) has been found in autism and psychotic disorders. Pupil dilation tracks events that warrant belief updating, likely reflecting the adjustment of neural gain. However, whether subclinical autistic or psychotic symptoms affect this adjustment and how they relate to learning ... -
Aberrant uncertainty processing is linked to psychotic‑like experiences, autistic traits, and is reflected in pupil dilation during probabilistic learning
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-28)Aberrant belief updating due to misestimation of uncertainty and an increased perception of the world as volatile (i.e., unstable) has been found in autism and psychotic disorders. Pupil dilation tracks events that warrant belief updating, likely refecting the adjustment of neural gain. However, whether subclinical autistic or psychotic symptoms afect this adjustment and how they relate to learning ... -
The ability of the strengths and difficulties questionnaire to detect mental health disorders in a child and adolescent outpatient clinic in Northern-Norway
(Master thesis; Mastergradsoppgave, 2010-05-03)The aim of the study was to examine the ability of the Strength and Difficulties Questionnaire (SDQ) to detect mental health disorders among patients referred to a child and adolescent outpatient clinic. The sample consisted of 100 participants between 5 and 17 years referred to an outpatient clinic in Northern-Norway. The SDQ-generated diagnostic predictions were compared to a gold standard to ... -
Ablasjonsbehandling av atrieflimmer ved UNN Tromsø
(Master thesis; Mastergradsoppgave, 2021-05-31)Bakgrunn Kateterablasjon er en veletablert behandlingsmetode for pasienter med symptomatisk atrieflimmer, og har vært utført ved Universitetssykehuset Nord-Norge siden 2009. Formålet med studien var å evaluere behandlingsresultatene etter kateterbasert ablasjonsbehandling av atrieflimmer ved UNN Tromsø fra 2013 til og med 2019. Materiale og metode Retrospektiv kohortstudie basert på 574 ...
