Viser treff 1374-1393 av 10152

    • Children’s sensitivity to eyebrow flash as an ostensive stimulus: a pilot study 

      Suhr, Emilie (Master thesis; Mastergradsoppgave, 2021-12-14)
      Ostensive signals are an integral part of normal everyday communication, a body of evidence indicates that some of them are innately recognizable to infants. The eyebrow flash has been suggested to be an ostensive signal by authors of human ethology studies. This have been shown little attention in the psychological field, this pilot study therefore has as goal of setting the basis for studying young ...
    • Children’s Well-being during the COVID-19 pandemic: Relationships with attitudes, family structure, and mothers’ Well-being 

      Martiny, Sarah E.; Thorsteinsen, Kjærsti; Parks-Stamm, Elizabeth J.; Olsen, Marte; Kvalø, Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-07)
      COVID-19 triggered social restrictions worldwide including the shutdown of schools. Whereas research has documented the negative effects on parents’ well-being, less is known about children’s well-being during the pandemic. We investigated the well-being, emotions, and COVID-19-related attitudes of 87 Norwegian elementary children (42 boys, 45 girls; M<sub>age</sub> = 9.66 years, SD = 1.77) and their ...
    • ChildTalks+: a study protocol of a pre-post controlled, paired design study on the use of preventive intervention for children of parents with a mental illness with focus on eating disorders 

      Farářová, Adéla; Papezova, Hana; Gricová, Jana; Štěpánková, Tereza; Čapek, Václav; Reedtz, Charlotte; Lauritzen, Camilla; van Doesum, Karin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-16)
      <p><b> Background:</b> Children of parents with a mental illness are at high risk of developing a mental disorder as a result of transgenerational transmission. Without effective intervention, they could form the next generation of psychiatric patients. ChildTalks+ is a preventive intervention involving four structured psychoeducational sessions designed for parents affected by a mental disorder ...
    • China's community-based strategy of universal preconception care in rural areas at a population level using a novel risk classification system for stratifying couples´ preconception health status 

      Zhou, Qiongjie; Zhang, Shikun; Wang, Qiaomei; Shen, Haiping; Tian, Weidong; Chen, Jingqi; Acharya, Ganesh; Li, Xiaotian (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-28)
      <i>Background</i>: Preconception care (PCC) is recommended for optimizing a woman’s health prior to pregnancy to minimize the risk of adverse pregnancy and birth outcomes. We aimed to evaluate the impact of strategy and a novel risk classification model of China´s “National Preconception Health Care Project” (NPHCP) in identifying risk factors and stratifying couples’ preconception health ...
    • Chinese herbal medicine Dengzhan Shengmai capsule as adjunctive treatment for ischemic stroke: A systematic review and meta-analysis of randomized clinical trials 

      Yang, Xiao-Ying; Wang, Li-Qiong; Li, Jin-Gen; Liang, Ning; Wang, Ying; Liu, Jian-Ping (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-09)
      <i>Objective</i>: The existing eligible randomized controlled trials (RCTs) were critically appraised for the effectiveness and safety of Chinese herbal medicine Dengzhan Shenmai for ischemic stroke.<p> <p><i>Design</i>: Systematic review and meta-analysis (CRD42016042914, http://www.crd.york.ac.uk/PROSPERO). Methods: Six electronic databases were searched from inception to May 2016. Risk ratio ...
    • Chinese herbal medicine for patients living with HIV in Guangxi province, China: an analysis of two registries 

      Sun, Jin; Jiang, Feng; Wen, Bin; Liu, Zhen-Wei; Han, Mei; Robinson, Nicola; McGrath, Nuala; Fei, Yu-Tong; Zhang, Ying; Li, Jing; Li, Wen-Yuan; Deng, Xin; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-25)
      Anti-Retroviral Therapy (ART) is the recommended first line therapy for patients with HIV. Since 2004, Chinese government has provided free Chinese herbal medicine (CHM) for Chinese HIV/AIDS patients. Data of living patients with HIV from the NFTCMP database and Center for Disease Control (CDC) database during 2003–2016 in Guangxi province was obtained and compared. Patients were divided into 3 ...
    • Chinese Herbal Medicines for the Treatment of Type A H1N1 Influenza : a Systematic Review of Randomized Controlled Trials 

      Chen, Wei; Lim, Chi Eung Danforn; Kang, Hong-Jun; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Chinese herbs are thought to be effective for type A H1N1 influenza. Series of Chinese herbs have been authorized recommended by the Chinese government, and until now a number of clinical trials of Chinese herbs for H1N1 influenza have been conducted. However, there is no critically appraised evidence such as systematic reviews or metaanalyses on potential benefits and harms of medicinal herbs for ...
    • Chinese Patent Medicine Shufeng Jiedu Capsules as an Adjuvant Therapy for Community-Acquired Pneumonia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials 

      Zhang, Xiao-Wen; Xia, Ru-Yu; Gao, Jia-Qi; Liu, Jin-Jun; Xu, De-Hao; Li, Xun; Hu, Xiao-Yang; Willcox, Merlin; Moore, Michael; Dai, Meng-Yuan; Trill, Jeanne; Fei, Yu-Tong; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-04)
      Background: Shufeng Jiedu (SFJD) capsules can be used as adjunctive treatment for patients with community-acquired pneumonia, but the effectiveness and safety of SFJD are not clear. This review aims to evaluate the effectiveness and safety of SFJD based on randomized controlled trials (RCTs).<p> <p>Methods: A systematic review was conducted by searching PubMed, Embase, Scopus, Web of Science, ...
    • Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia. A meta-analysis of randomized controlled trials 

      Grimsgaard, Sameline; Zhang, Jing; Yi, Shi; Alræk, Terje; Fønnebø, Vinjar; Liu, Jianping (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-11-23)
      Extracts of Chinese red yeast rice (RYR, a traditional dietary seasoning of Monascus purpureus) contains several active ingredients including lovastatin, and several trials of its possible lipid-lowering effects have been conducted. This meta-analysis assesses the effectiveness and safety of RYR preparations on lipid modification in primary hyperlipidemia. We included randomized controlled trials ...
    • Chitinolytic enzymes contribute to the pathogenicity of Aliivibrio salmonicida LFI1238 in the invasive phase of cold-water vibriosis 

      Skåne, Anna; Edvardsen, Per Kristian Thorén; Cordara, Gabriele; Loose, Jennifer Sarah Maria; Leitl, Kira Daryl; Krengel, Ute; Sørum, Henning; Askarian, Fatemeh; Vaaje-Kolstad, Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-08)
      Background - Aliivibrio salmonicida is the causative agent of cold-water vibriosis in salmonids (Oncorhynchus mykiss and Salmo salar L.) and gadidae (Gadus morhua L.). Virulence-associated factors that are essential for the full spectrum of A. salmonicida pathogenicity are largely unknown. Chitin-active lytic polysaccharide monooxygenases (LPMOs) have been indicated to play roles in both chitin ...
    • Chitosan in Mucoadhesive Drug Delivery: Focus on Local Vaginal Therapy 

      Andersen, Toril; Bleher, Stefan; Flaten, Gøril Eide; Tho, Ingunn; Mattsson, Sofia; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-07)
      Mucoadhesive drug therapy destined for localized drug treatment is gaining increasing importance in today’s drug development. Chitosan, due to its known biodegradability, bioadhesiveness and excellent safety profile offers means to improve mucosal drug therapy. We have used chitosan as mucoadhesive polymer to develop liposomes able to ensure prolonged residence time at vaginal site. Two types of ...
    • Chitosan Lecithin Nanoparticles with New Chemical Entity. Antimicrobial Evaluation 

      Hemmingsen, Lisa Myrseth (Master thesis; Mastergradsoppgave, 2015-05-13)
      Chronic wounds are often colonized with biofilm-producing bacteria, such as Staphylococcus epidermidis, and these wounds often have high degree of complexity and are often challenging to treat. There is a high resistance to the traditional antimicrobial treatments and that is why these infections sometimes are persistent. Photodynamic therapy (PDT) is proposed as a potential solution to the problems ...
    • Chitosan Lecithin Nanoparticles with New Chemical Entity. Nanotoxicity Evaluation 

      Kangu, Lloyd Mbugua (Master thesis; Mastergradsoppgave, 2016-05-12)
      Chronic skin wounds are an exponentially increasing problem on a world basis, and are often hard to treat due to bacterial biofilm formation and resistance to different antibiotic treatments. Antimicrobial photodynamic therapy (aDPT) shows promise in resolving this issue, but clinical based treatments have yet to be established although photodynamic therapy is used for other conditions. A new ...
    • Chitosan-based delivery system enhances antimicrobial activity of chlorhexidine 

      Hemmingsen, Lisa Myrseth; Panchai, Pimmat; Julin, Kjersti; Basnet, Purusotam; Nystad, Mona; Johannessen, Mona; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-29)
      Infected chronic skin wounds and other skin infections are increasingly putting pressure on the health care providers and patients. The pressure is especially concerning due to the rise of antimicrobial resistance and biofilm-producing bacteria that further impair treatment success. Therefore, innovative strategies for wound healing and bacterial eradication are urgently needed; utilization ...
    • Chitosan-based drug delivery system for a new chemical entity for photodynamic wound therapy 

      Hadafow, Muna Abukar (Master thesis; Mastergradsoppgave, 2014-05-24)
      Due to inappropriate or excessive use of antibiotics, multi resistance has become a global problem which threatens the public health. Photodynamic therapy has emerged as a promising and important approach in many fields of drug therapy. In recent years, many studies on photodynamic therapy for infections have shown promising results. One of the advantages of using PDT in treatment of infections is ...
    • Chitosan-Based Nanomedicine to Fight Genital Candida Infections: Chitosomes 

      Andersen, Toril; Mishchenko, Ekaterina; Flaten, Gøril Eide; Sollid, Johanna U Ericson; Mattsson, Sofia; Tho, Ingunn; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-04)
      Vaginal infections are associated with high recurrence, which is often due to a lack of efficient treatment of complex vaginal infections comprised of several types of pathogens, especially fungi and bacteria. Chitosan, a mucoadhesive polymer with known antifungal effect, could offer a great improvement in vaginal therapy; the chitosan-based nanosystem could both provide antifungal effects and ...
    • Chitosan-coated liposomes for topical vaginal therapy: Assuring localized drug effect 

      Jøraholmen, May Wenche; Vanić, Željka; Tho, Ingunn; Škalko-Basnet, Nataša (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      The choice of drug therapy in pregnant patients suffering from vaginal infections is limited by the safety profile of the drug. Assuring the efficient topical therapy to avoid systemic absorption is considered the best therapy option. Chitosan-coated liposomes have been developed and optimized to assure localized therapy of clotrimazole. Chitosan was selected as mucoadhesive polymer both to prolong ...
    • Chitosan-modified liposomes for delivery of membrane-active antimicrobials – exploring the role of the polymer 

      Panchai, Pimmat (Master thesis; Mastergradsoppgave, 2022-05-12)
      Antimicrobial resistance in skin injury infections is becoming a rising problem as more conventional antimicrobials become ineffective in resistant infections. Therefore, developing novel effective antimicrobials while promoting wound healing is urgently needed. Membrane-active antimicrobials, such as antimicrobial peptides (AMPs), display promising antimicrobial activity, and could potentially solve ...
    • Chitosomes-In-Chitosan Hydrogel for Acute Skin Injuries: Prevention and Infection Control 

      Hemmingsen, Lisa Myrseth; Julin, Kjersti; Ahsan, Luqman; Basnet, Purusotam; Johannessen, Mona; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-12)
      Burns and other skin injuries are growing concerns as well as challenges in an era of antimicrobial resistance. Novel treatment options to improve the prevention and eradication of infectious skin biofilm-producing pathogens, while enhancing wound healing, are urgently needed for the timely treatment of infection-prone injuries. Treatment of acute skin injuries requires tailoring of formulation to ...
    • Chlamydia pecorum associated with an outbreak of infectious keratoconjunctivitis in semi-domesticated reindeer in Sweden 

      Sanchez Romano, Javier; Leijon, Mikael; Hagström, Åsa; Jinnerot, Tomas; Rockström, Urlika; Tryland, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-05)
      Infectious keratoconjunctivitis (IKC), the most common ocular disease in ruminants worldwide, has affected semi-domesticated Eurasian reindeer (<i>Rangifer tarandus tarandus</i>) for over 100 years, both as individual cases and in outbreaks affecting tens to hundreds of animals. Recurrent IKC outbreaks have been affecting a semi-domesticated reindeer herd in Östra Kikkejaure (Norrbotten county, ...