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    • Decentralized nursing education in Northern Norway: towards a sustainable recruitment and retention model in rural Arctic healthcare services 

      Norbye, Bente; Skaalvik, Mari Wolff (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Decentralized nursing education (DNE) was established at Tromsø University College in 1990 and has since become a part of the bachelor programme in nursing at UiT The Arctic University of Norway. The objective of the study was to investigate whether and to what degree the first DNE programme established in Norway has contributed to recruitment and retention of registered nurses (RNs) in rural ...
    • Decentralized nursing education to establish a Circumpolar Northern and Indigenous workforce. 

      Skaalvik, Mari Wolff; Norbye, Bente; Butler, Lorna; Exner-Pirot, Heather (Conference object; Konferansebidrag, 2016-09)
      The project is aiming to improve the quality and quantity of northern nursing programs through NNEN to meet the challenge to deliver a stable, culturally competent health workforce in northern areas with indigenous populations. The aim is to be achieved through sharing best practices and research.
    • Deciphering human cell type enriched transcriptomes across tissue types and the functional study of the endothelial enriched protein KANK3 

      Öling, Sofia Maria (Doctoral thesis; Doktorgradsavhandling, 2023-11-13)
      The identification of cell type-specific genes and their modification under certain conditions is essential for our understanding of the human body. Such knowledge also allows us to study the function of uncharacterised genes in the correct cell type. Single-cell RNA sequencing (scRNAseq) can be used to profile different cell types, but cell removal and processing can introduce artifacts. In the ...
    • Deciphering Normal Blood Gene Expression Variation-The NOWAC Postgenome Study 

      Dumeaux, vanessa; Nuel, G; Børresen-Dale, Anne-Lise; Olsen, Karina Standahl; Paulssen, Ruth H; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
    • Deciphering the landscape of host barriers to Listeria monocytogenes infection 

      Zhang, Ting; Abel, Sören; Abel zur Wiesch, Pia; Sasabe, Jumpei; Davis, Brigid M.; Higgins, Darren E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-30)
      <i>Listeria monocytogenes</i> is a common food-borne pathogen that can disseminate from the intestine and infect multiple organs. Here, we used sequence tag-based analysis of microbial populations (STAMP) to investigate <i>L. monocytogenes</i> population dynamics during infection. We created a genetically barcoded library of murinized <i>L. monocytogenes</i> and then used deep sequencing to track ...
    • Decision making in endodontics among the endodontic profession and general practitioners in Norway 

      Berg, Lars Martin (Master thesis; Mastergradsoppgave, 2010-06-10)
      ABSTRACT Background: Considerable variation between and within groups of NEF members and general practitioners (GPs) has been shown in the choice of endodontic retreatment options. However, uniform criteria and consensus in decision-making would be of importance when the clinical training in the dental school is arranged in a community setting by GPs employed as clinical instructors. Objectives: ...
    • Decision making in vaccine hesitant parents and pregnant women – An integrative review 

      Sivertsen, Nina; Smith, Susan E.; Lines, Lauren Elizabeth; De Bellis, Anita (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-15)
      Objectives: : Vaccine refusal is increasing in Australia and is a major concern in high- and middle income countries. There is evidence to suggest that some parents, even those who elect to immunise, may be vaccine hesitant with some manipulating the schedule by excluding or delaying some vaccines. The aim of this review was to gain an understanding of factors that influence vaccine decision-making ...
    • Decision-making in Norwegian child welfare services- The impact of case characteristics on decision-making from referral to concluded investigation 

      Rustad, Kirsten Buck (Doctoral thesis; Doktorgradsavhandling, 2024-01-18)
      The thesis explores how case characteristics impact decision-making in the Norwegian child welfare service. The following decisions were studied: i) the initial screening decision, ii) the extent of an investigation, and iii) the dismissal of cases when the family refuse interventions. Previous research has identified differences in case trajectory between agencies. The impact of case characteristics ...
    • Decisional responsibility for mechanical ventilation and weaning: an international survey 

      Rose, Louise; Blackwood, Bronagh; Egerod, Ingrid; Haugdahl, Hege Selnes; Hofhuis, Josè; Isfort, Michael; Kydonaki, Kalliopi; Schubert, Maria; Sperlinga, Ricardo; Spronk, Peter; Storli, Sissel Lisa; McAuley, Daniel; Schultz, Marcus J (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-12-14)
      Introduction: Optimal management of mechanical ventilation and weaning requires dynamic and collaborative decision making to minimize complications and avoid delays in the transition to extubation. In the absence of collaboration, ventilation decision making may be fragmented, inconsistent, and delayed. Our objective was to describe the professional group with responsibility for key ventilation ...
    • Decisions on sick leave certifications for acute airways infections based on vignettes: A cross-sectional survey of GPs in Norway and Poland 

      Halvorsen, Peder Andreas; Wennevold, Katrine; Fleten, Nils; Muras, Magdalena; Kowalczyk, Anna; Godycki-Cwirko, Maciek; Melbye, Hasse (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-02-17)
      Objective. To explore whether frequency and duration of sick-leave certifi cation for acute airway infections differ between general practitioners (GPs) in Poland and Norway. Design . Cross-sectional survey. Setting. Educational courses for GPs. Intervention. We used a questionnaire with four vignettes presenting patients with symptoms consistent with pneumonia, sinusitis, common cold, and ...
    • Decisions on statin therapy by patients’ opinions about survival gains: cross sectional survey of general practitioners 

      Halvorsen, Peder Andreas; Aasland, Olaf Gjerløw; Kristiansen, Ivar Sønbø (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-07-03)
      Background: Guidelines for primary prevention of cardiovascular disease provide little guidance on how patients’ preferences should be taken into account. We wanted to explore whether general practitioners (GPs) are sensitive to patient preferences regarding survival gains from statin therapy. Methods: In a cross sectional, online survey 3,270 Norwegian GPs were presented with a 55 year old patient ...
    • Decline in resting heart rate, its association with other variables, and its role in cardiovascular disease The Tromsø Study 

      Sharashova, Ekaterina (Doctoral thesis; Doktorgradsavhandling, 2017-02-10)
      Background: Resting heart rate (RHR) is an easily measured cardiovascular parameter that is considered an independent predictor of cardiovascular disease (CVD) and mortality in the general population. However, results on the association between RHR and these outcomes are inconsistent, and studies on longitudinal trends in RHR and the role of long-term changes in RHR in CVD and mortality are scarce. ...
    • Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis 

      Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten Wang; Storheim, Kjersti; Brox, Jens Ivar; Solberg, Tore; Rekeland, Frode; Franssen, Eric; Weber, Clemens; Brisby, Helena; Grundnes, Oliver; Algaard, Knut; Bøker, Tordis; Banitalebi, Hasan; Indrekvam, Kari; Hellum, Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-05)
      BACKGROUND In patients with lumbar spinal stenosis and degenerative spondylolisthesis, it is uncertain whether decompression surgery alone is noninferior to decompression with instrumented fusion. METHODS We conducted an open-label, multicenter, noninferiority trial involving patients with symptomatic lumbar stenosis that had not responded to conservative management and who had single-level ...
    • Decompressive hemicraniectomy for space-occupying brain infarction: Nationwide population-based registry study 

      Anke, Pablo; Pedersen, Lars Kjelsberg; Mathiesen, Ellisiv Bøgeberg; Ingebrigtsen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-14)
      Objective: We analyzed data from the Norwegian Stroke Registry (NSR) to study access to and outcomes of decompressive hemicraniectomy for brain infarction in a nationwide routine clinical setting. We also discretionary assessed whether the outcomes were comparable with those achieved in randomized controlled trials (RCTs), and whether the use was in accordance with guidelines. Methods: The NSR ...
    • Decrease in use of manual vacuum aspiration in postabortion care in Malawi: A cross-sectional study from three public hospitals, 2008-2012 

      Odland, Maria Lisa; Rasmussen, Hanne; Jacobsen, Geir Wenberg; Kafulafula, UK; Chamanga, P; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-06-25)
    • The decreasing prevalence of nonrefractive visual impairment in older Europeans: a meta-analysis of published and unpublished data 

      Delcourt, Cécile; Le Goff, Mélanie; von Hanno, Therese; Mirshahi, Alireza; Khawaja, Anthony P.; Verhoeven, Virginie J.M.; Hogg, Ruth E.; Anastosopoulos, Eleftherios; Cachulo, Maria Luz; Höhn, René; Wolfram, Christian; Bron, Alain; Miotto, Stefania; Carrière, Isabelle; Colijn, Johanna M.; Buitendijk, Gabriëlle H.S.; Evans, Jennifer; Nitsch, Dorothea; Founti, Panayiota; Yip, Jennifer L.Y.; Pfeiffer, Norbert; Creuzot-Garcher, Catherine; Silva, Rufino; Piermarocchi, Stefano; Topouzis, Fotis; Bertelsen, Geir; Foster, Paul J.; Fletcher, Astrid; Klaver, Caroline C.W.; Korobelnik, Jean-François (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-13)
      <p><i>Topic</i>: To estimate the prevalence of nonrefractive visual impairment and blindness in European persons 55 years of age and older.</p> <p><i>Clinical Relevance</i>: Few visual impairment and blindness prevalence estimates are available for the European population. In addition, many of the data collected in European population-based studies currently are unpublished and have not been ...
    • Decreasing trends in number of depot medroxyprogesterone acetate starters in Norway - a cross-sectional study 

      Roksvaag, Ingvild; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-20)
      <i>Introduction - </i>In this study, we examined changes in depot medroxyprogesterone acetate (DMPA) prescriptions over a time‐period when new professions started prescribing, and when the method gained some negative media attention.<br><br> <i>Material and methods - </i>The Norwegian Prescription Database provided data on hormonal contraception from 2006 through 2012. We estimated the annual number ...
    • The "deep caries" challenge. Prevalence and management of deep carious lesions in Northern Norway. 

      Stangvaltaite, Lina (Doctoral thesis; Doktorgradsavhandling, 2015-10-22)
      The overall aim of this doctoral thesis was to increase the understanding and knowledge of the prevalence and management of deep carious lesions. The prevalence of dental caries in Norway was among the highest in the world in the middle of 20th century. Though it has significantly declined, there are indications that the prevalence of caries in Northern Norway is higher than in the rest of the ...
    • Deep Learning Denoising Improves and Homogenizes Patient [18F]FDG PET Image Quality in Digital PET/CT 

      Weyts, Kathleen; Quak, Elske; Licaj, Idlir; Ciappuccini, Renaud; Lasnon, Charline; Corroyer-Dulmont, Aurélien; Foucras, Gauthier; Bardet, Stéphane; Jaudet, Cyril (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-04)
      Given the constant pressure to increase patient throughput while respecting radiation protection, global body PET image quality (IQ) is not satisfactory in all patients. We first studied the association between IQ and other variables, in particular body habitus, on a digital PET/CT. Second, to improve and homogenize IQ, we evaluated a deep learning PET denoising solution (Subtle PET<sup>TM</sup>) ...
    • Deep learning-based image analysis reveals significant differences in the number and distribution of mucosal CD3 and γδ T cells between Crohn's disease and ulcerative colitis 

      Røyset, Elin Synnøve; Pettersen, Henrik Sahlin; Xu, Weili; Larbi, Anis; Sandvik, Arne Kristian; Steigen, Sonja Eriksson; Catalan-Serra, Ignacio; Bakke, Ingunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-23)
      Colon mucosae of ulcerative colitis (UC) and Crohn's disease (CD) display differences in the number and distribution of immune cells that are difficult to assess by eye. Deep learning-based analysis on whole slide images (WSIs) allows extraction of complex quantitative data that can be used to uncover different inflammatory patterns. We aimed to explore the distribution of CD3 and γδ T cells in colon ...