Blar i forfatter Det helsevitenskapelige fakultet "Emaldi, Maite"

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    • Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer 

      Nunes-Xavier, Caroline Elisabeth; Emaldi, Maite; Guldvik, Ingrid Jenny; Ramberg, Håkon; Tasken, Kristin Austlid; Mælandsmo, Gunhild Mari; Fodstad, Øystein; Llarena, Roberto; Pulido, Rafael; Lopez, José I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-24)
      Prostate cancer diagnosis and early stratification is an important aspect to avoid undertreatment of high-risk prostate cancer patients. Major Vault Protein (MVP) has been proposed as a prognostic biomarker in prostate cancer. PTEN and the immune checkpoint protein B7-H3 interact with MVP and are important in prostate cancer progression and therapy response. We evaluated the expression of MVP by ...

    • The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma 

      Nunes-Xavier, Caroline Elisabeth; Emaldi, Maite; Mingo, Janire; Øyjord, Tove Ragnhild; Mælandsmo, Gunhild Mari; Fodstad, Øystein; Errarte, Peio; Larrinaga, Gorka; Llarena, Roberto; López, José I.; Pulido, Rafael (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-05)
      Renal cancer cells constitute a paradigm of tumor cells with a glycolytic reprogramming which drives metabolic alterations favouring cell survival and transformation. We studied the expression and activity of pyruvate dehydrogenase kinases (PDK1-4), key enzymes of the energy metabolism, in renal cancer cells. We analysed the expression, subcellular distribution and clinicopathological correlations ...