• Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis 

      Hudson, Jemma; Cruickshank, Moira; Quinton, Richard; Aucott, Lorna; Aceves-Martins, Magaly; Gillies, Katie; Bhasin, Shalender; Snyder, Peter J; Ellenberg, Susan S; Grossmann, Mathis; Travison, Thomas G; Gianatti, Emily J; van der Schouw, Yvonne T; Emmelot-Vonk, Marielle H; Giltay, Erik J; Hackett, Geoff; Ramachandran, Sudarshan; Svartberg, Johan; Hildreth, Kerry L; Groti Antonic, Kristina; Brock, Gerald B; Tenover, J Lisa; Tan, Hui Meng; Kong, Christopher Ho Chee; Tan, Wei Shen; Marks, Leonard S; Ross, Richard J; Schwartz, Robert S; Manson, Paul; Roberts, Stephen; Andersen, Marianne; Magnussen, Line Velling; Hernández, Rodolfo; Oliver, Nick; Wu, Frederick; Dhillo, Waljit S; Bhattacharya, Siladitya; Brazzelli, Miriam; Jayasena, Channa N (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-09)
      Background Testosterone is the standard treatment for male hypogonadism, but there is uncertainty about its cardiovascular safety due to inconsistent findings. We aimed to provide the most extensive individual participant dataset (IPD) of testosterone trials available, to analyse subtypes of all cardiovascular events observed during treatment, and to investigate the effect of incorporating data ...
    • Symptomatic benefits of testosterone treatment in patient subgroups: a systematic review, individual participant data meta-analysis, and aggregate data meta-analysis 

      Hudson, Jemma; Cruickshank, Moira; Quinton, Richard; Aucott, Lorna; Wu, Frederick; Grossmann, Mathis; Bhasin, Shalender; Snyder, Peter J; Ellenberg, Susan S; Travison, Thomas G; Brock, Gerald B; Gianatti, Emily J; van der Schouw, Yvonne T; Emmelot-Vonk, Marielle H; Giltay, Erik J; Hackett, Geoff; Ramachandran, Sudarshan; Svartberg, Johan; Hildreth, Kerry L; Antonic, Kristina Groti; Tenover, Joyce Lisa; Tan, Hui Meng; Ho Chee Kong, Christopher; Tan, Wei Shen; Marks, Leonard S; Ross, Richard J; Schwartz, Robert S; Manson, Paul; Roberts, Stephen A; Skovsager Andersen, Marianne; Velling Magnussen, Line; Aceves-Martins, Magaly; Gillies, Katie; Hernández, Rodolfo; Oliver, Nick; Dhillo, Waljit S; Bhattacharya, Siladitya; Brazzelli, Miriam; Jayasena, Channa N (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-04)
      Background Testosterone replacement therapy is known to improve sexual function in men younger than 40 years with pathological hypogonadism. However, the extent to which testosterone alleviates sexual dysfunction in older men and men with obesity is unclear, despite the fact that testosterone is being increasingly prescribed to these patient populations. We aimed to evaluate whether subgroups of men ...