Blar i forfatter Det helsevitenskapelige fakultet "Flanagan, James M."

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    • Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis 

      van Veldhoven, Karin; Polidoro, Silvia; Baglietto, Laura; Severi, Gianluca; Sacerdote, Carlotta; Panico, Salvatore; Mattiello, Amalia; Palli, Domenico; Masala, Giovanna; Krogh, Vittorio; Agnoli, Claudia; Tumino, Rosario; Frasca, Graziella; Flower, Kirsty; Curry, Ed; Orr, Nicholas; Tomczyk, Katarzyna; Jones, Michael E.; Ashworth, Alan; Swerdlow, Anthony; Chadeau-Hyam, Marc; Lund, Eiliv; Garcia-Closas, Montserrat; Sandanger, Torkjel M; Flanagan, James M.; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-04)
      Background: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast cancer. We report on three independent prospective nested case-control studies from the European ...