• Epidermal growth factor receptor signaling enhances the proinflammatory effects of staphylococcus aureus gamma-toxin on the mucosa 

      Gillman, Aaron N.; Breshears, Laura M.; Kistler, Charles K.; Finnegan, Patrick M.; Torres, Victor J.; Schlievert, Patrick M.; Peterson, Marnie L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-28)
      Staphylococcus aureus (S. aureus) produces many different exotoxins including the gamma-toxins, HlgAB and HlgCB. Gamma-toxins form pores in both leukocyte and erythrocyte membranes, resulting in cell lysis. The genes encoding gamma-toxins are present in most strains of S. aureus, and are commonly expressed in clinical isolates recovered from menstrual Toxic Shock Syndrome (mTSS) patients. This study ...