Blar i forfatter Det helsevitenskapelige fakultet "Haugen, Peik"

Viser treff 1-3 av 3

    • Construction of a fur null mutant and RNA-sequencing provide deeper global understanding of the Aliivibrio salmonicida Fur regulon 

      Thode, Sunniva Katharina; Bækkedal, Cecilie; Söderberg, Jenny Johansson; Hjerde, Erik; Hansen, Hilde; Haugen, Peik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-13)
      <i>Background:</i> The ferric uptake regulator (Fur) is a transcription factor and the main regulator of iron acquisition in prokaryotes. When bound to ferric iron, Fur recognizes its DNA binding site and generally executes its function by repressing transcription of its target genes. Due to its importance in virulence, the Fur regulon is well studied for several model bacteria. In our previous ...

    • Cyanobacterial ribosomal RNA genes with multiple, endonuclease-encoding group I introns 

      Bhattacharya, Debashish; Haugen, Peik; Palmer, Jeffrey D.; Turner, Seán; Lewis, Louise A.; Pryer, Kathleen M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2007-09-08)
      Background: Group I introns are one of the four major classes of introns as defined by their distinct splicing mechanisms. Because they catalyze their own removal from precursor transcripts, group I introns are referred to as autocatalytic introns. Group I introns are common in fungal and protist nuclear ribosomal RNA genes and in organellar genomes. In contrast, they are rare in all other ...

    • The recent transfer of a homing endonuclease gene 

      Haugen, Peik; Wikmark, Odd-Gunnar; Vader, Anna; Coucheron, Dag H.; Sjøttem, Eva; Johansen, Steinar D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
      The myxomycete Didymium iridis (isolate Panama 2) contains a mobile group I intron named Dir.S956-1 after position 956 in the nuclear small subunit (SSU) rRNA gene. The intron is efficiently spread through homing by the intron-encoded homing endonuclease I-DirI. Homing endonuclease genes (HEGs) usually spread with their associated introns as a unit, but infrequently also spread independent of ...