• Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis 

      Chemaly, Melody; Marlevi, David; Iglesias, Maria Jesus; Lengquist, Mariette; Kronqvist, Malin; Bos, Daniel; van Dam-Nolen, Dianne H. K.; van der Kolk, Anja; Hendrikse, Jeroen; Kassem, Mohamed; Matic, Ljubica; Odeberg, Jacob; de Vries, Margreet R.; Kooi, M. Eline; Hedin, Ulf (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-24)
      Background: Intraplaque hemorrhage (IPH) is a hallmark of atherosclerotic plaque instability. Biliverdin reductase B (BLVRB) is enriched in plasma and plaques from patients with symptomatic carotid atherosclerosis and functionally associated with IPH. Objective: We explored the biomarker potential of plasma BLVRB through (1) its correlation with IPH in carotid plaques assessed by magnetic resonance ...