• Epigenomic and transcriptomic approaches in the post-genomic era: Path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart 

      Perrino, Cinzia; Barabási, Albert-Laszló; Condorelli, Gianluigi; Davidson, Sean Michael; De Windt, Leon; Dimmeler, Stefanie; Engel, Felix Benedikt; Hausenloy, Derek John; Hill, Joseph Addison; Van Laake, Linda Wilhelmina; Lecour, Sandrine; Leor, Jonathan; Madonna, Rosalinda; Mayr, Manuel; Prunier, Fabrice; Sluijter, Joost Petrus Geradus; Schulz, Rainer; Thum, Thomas; Ferdinandy, Péter (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-29)
      Despite advances in myocardial reperfusion therapies, acute myocardial ischaemia/reperfusion injury and consequent ischaemic heart failure represent the number one cause of morbidity and mortality in industrialized societies. Although different therapeutic interventions have been shown beneficial in preclinical settings, an effective cardioprotective or regenerative therapy has yet to be successfully ...
    • ESC working group on cellular biology of the heart: Position paper for Cardiovascular Research: Tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure 

      Madonna, Rosalinda; Van Laake, Linda W.; Bøtker, Hans Erik; Davidson, Sean M.; De Caterina, Raffaele; Engel, Felix B.; Eschenhagen, Thomas; Fernandez-Aviles, Francesco; Hausenloy, Derek J.; Hulot, Jean-Sebastien; Lecour, Sandrine; Leor, Jonathan; Menasché, Philippe; Pesce, Maurizio; Perrino, Cinzia; Prunier, Fabrice; Van Linthout, Sophie; Ytrehus, Kirsti; Zimmermann, Wolfram-Hubertus; Ferdinandy, Péter; Sluijter, Joost P.G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-17)
      Morbidity and mortality from ischaemic heart disease (IHD) and heart failure (HF) remain significant in Europe and are increasing worldwide. Patients with IHD or HF might benefit from novel therapeutic strategies, such as cellbased therapies. We recently discussed the therapeutic potential of cell-based therapies and provided recommendations on how to improve the therapeutic translation of these ...
    • Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology 

      Sluijter, Joost Petrus Geradus; Davidson, Sean Michael; Boulanger, Chantal M; Buzas, Edit Iren; De Kleijn, Dominique P.V.; Engel, Felix Benedikt; Giricz, Zoltán; Hausenloy, Derek J.; Kishore, Raj; Lecour, Sandrine; Leor, Jonathan; Madonna, Rosalinda; Perrino, Cinzia; Prunier, Fabrice; Sahoo, Susmita; Schiffelers, Ray Michel; Schulz, Rainer; Van Laake, Linda Wilhelmina; Ytrehus, Kirsti; Ferdinandy, Péter (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-02)
      Extracellular vesicles (EVs)—particularly exosomes and microvesicles (MVs)—are attracting considerable interest in the cardiovascular field as the wide range of their functions is recognized. These capabilities include transporting regulatory molecules including different RNA species, lipids, and proteins through the extracellular space including blood and delivering these cargos to recipient ...