Blar i forfatter Det helsevitenskapelige fakultet "Paavonen, Timo"

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    • Evaluation Challenges in the validation of B7-H3 as oral tongue cancer prognosticator 

      Sieviläinen, Meri; Wirsing, Anna Maria; Hyytiäinen, Aini; Almahmoudi, Rabeia; Rodrigues, Priscila; Bjerkli, Inger-Heidi; Åström, Pirjo; Toppila‑Salmi, Sanna; Paavonen, Timo; Coletta, Ricardo D.; Hadler‑Olsen, Elin; Salo, Tuula; Al‑Samadi, Ahmed (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-21)
      B7-H3 was the only molecule identified with prognostic potential from a recent systematic review of the prognostic value of immune checkpoints in oral cancer. We aimed to validate this finding in a multicenter international cohort. We retrospectively retrieved 323 oral tongue squamous cell carcinoma (OTSCC) samples from three different countries (Brazil, Finland, and Norway) for immunostaining and ...