Browsing Det helsevitenskapelige fakultet by Author "Rønning, Torunn Gresdal"
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Phenotypic and genotypic characterisation of thymine auxotrophy in Escherichia coli isolated from a patient with recurrent bloodstream infection
Jakovljev, Aleksandra; Afset, Jan Egil; Haugum, Kjersti; Steinum, Harald Otto; Rønning, Torunn Gresdal; Samuelsen, Ørjan; Ås, Christina Gabrielsen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-08)Introduction<p> <p>Thymine auxotrophic in vitro mutants of Escherichia coli were first reported in the mid-20th century. Later, thymine-dependent clinical strains of E. coli as well as other Enterobacterales, Enterococcus faecalis and Staphylococcus aureus have been recognized as the cause of persistent and recurrent infections. <p>Objectives <p>The aim of this study was to characterize the ... -
Silenced vanA gene cluster on a transferable plasmid cause outbreak of vancomycin variable enterococci
Sivertsen, Audun; Pedersen, Torunn Annie; Larssen, Kjersti Wik; Bergh, Kåre; Rønning, Torunn Gresdal; Radtke, Andreas; Hegstad, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-02)We report an outbreak of vancomycin-variable vanA+ enterococci (VVE) able to escape phenotypic detection by current guide- lines and demonstrate the molecular mechanisms for in vivo switching into vancomycin resistance and horizontal spread of the vanA cluster. Forty-eight vanA+ Enterococcus faecium isolates and one Enterococcus faecalis isolate were analyzed for clonality with pulsed-field ...