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norskBrowsing Det helsevitenskapelige fakultet by Author "Åsberg, Anders"
Now showing items 1-9 of 9
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Blood Pressure Treatment in Kidney Transplant Recipients - Can We Improve?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-25)<i>Background</i> - Hypertension in kidney transplant (KTx) recipients is common, affecting both patient and graft survival. Annual data from the Norwegian Renal Registry reveal that <50% of adult (>18 y) KTx recipients reach target blood pressure (BP) ≤130/80 mm Hg. The aim of this study was to identify the determinants of failure to achieve BP control.<br><br> <i>Methods</i> - In conjunction ... -
Endothelial function after pancreas transplantation - A single-center observational study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)<i>Background</i> - Patients with diabetes mellitus treated with successful pancreas transplantation (PTX) normalize hyperglycemia, but are exposed to immunosuppressive drugs that may impair endothelial function. This study aimed to evaluate endothelial function in single PTX recipients.<p><p> <i>Methods</i> - Flow‐mediated dilatation (FMD) in the brachial artery was measured by ultrasound 8 weeks ... -
Haptoglobin 2-2 Genotype, Patient, and Graft Survival in Renal Transplant Recipients
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-22)Background:<br> Cardiovascular disease is the leading cause of death in renal transplant recipients (RTRs). An association between haptoglobin genotype 2 - 2 and cardiovascular disease has been found in patients with diabetes mellitus and liver transplant recipients. To date, the role of haptoglobin genotype after renal transplantation has not been studied. <br>Methods:<br> In this single centre ... -
Kidney biopsy diagnosis in childhood in the Norwegian Kidney Biopsy Registry and the long-term risk of kidney replacement therapy: a 25-year follow-up
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-22)Background There is scarce information on biopsy-verifed kidney disease in childhood and its progression to chronic kidney disease stage 5 (CKD 5). This study aims to review biopsy fndings in children, and to investigate risk of kidney replacement therapy (KRT).<p> <p>Methods We conducted a retrospective long-term follow-up study of children included in the Norwegian Kidney Biopsy Registry (NKBR) ... -
Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-18)Background: Higher incidence of malignancy and infectious diseases in kidney transplant recipients is related to immunosuppressive treatment after transplantation and the recipient’s native immune system. The complement system is an essential component of the innate immunity. The aim of the present study was to investigate the association of effector molecules of the lectin complement pathway with ... -
Outcomes in pancreas transplantation with exocrine drainage through a duodenoduodenostomy versus duodenojejunostomy
(Journal article; Tidsskriftartikkel, 2017-08-23)Until recently, pancreas transplantation has mostly been performed with exocrine drainage via duodenojejunostomy (DJ). Since 2012, DJ was substituted with duodenoduodenostomy (DD) in our hospital, allowing endoscopic access for biopsies. This study assessed safety profiles with DD versus DJ procedures and clinical outcomes with the DD technique in pancreas transplantation. DD patients (n = 117; 62 ... -
Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-24)<p><i>Objective</i>: The major n-6 polyunsaturated fatty acids linoleic acid (LA) and arachidonic acid (AA) play a role in inflammation and glucose metabolism, which could affect patient and renal transplant survival.</p> <p><i>Design and methods</i>: In this single center cohort study of 1988 Norwegian renal transplant recipients, we assessed associations between plasma levels of LA and AA at ... -
Validation of diagnostic utility of fasting plasma glucose and HbA1c in stable renal transplant recipients one year after transplantation
(Journal article; Peer reviewed, 2019-01-10)<b>Background</b><br> The use of HbA1c ≥6.5% for diagnosis of diabetes has been challenged for post-transplantation diabetes mellitus (PTDM) also known as new onset diabetes after transplantation (NODAT) due to a low sensitivity early after renal transplantation. PTDM diagnosed with an oral glucose tolerance test (OGTT) is highly predictable for long-term patient mortality. HbA1c was introduced for ... -
Visceral fat is strongly associated with post-transplant diabetes mellitus and glucose metabolism 1 year after kidney transplantation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-16)Body composition after kidney transplantation is linked to glucose metabolism, and impaired glucose metabolism is associated with increased risk of cardiovascular events and death. One year after transplantation we examined 150 patients for new-onset diabetes performing OGTTs and body composition measurements including visceral adipose tissue (VAT) content from dual-energy X-ray absorptiometry ...
