Browsing Det helsevitenskapelige fakultet by Author "Ebert, Natalie"

Now showing items 1-11 of 11

    • Comparability of plasma iohexol clearance across population-based cohorts 

      Eriksen, Bjørn Odvar; Schaeffner, Elke; Melsom, Toralf; Ebert, Natalie; van der Giet, Markus; Gudnason, Vilmundur; Indridasson, Olafur S.; Karger, Amy B.; Levey, Andrew S.; Schuchardt, Mirjam; Sørensen, Liv Karin; Pálsson, Runólfur (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-23)
      Rationale & Objective: Glomerular filtration rate (GFR) estimation based on creatinine or cystatin C level is currently the standard method for assessing GFR in epidemiologic research and clinical trials despite several important and well-known limitations. Plasma iohexol clearance has been proposed as an inexpensive method for measuring GFR that could replace estimated GFR in many research ...

    • Cystatin C-Based Equation to Estimate GFR without the Inclusion of Race and Sex 

      Pottel, Hans; Björk, Jonas; Rule, Andrew D.; Ebert, Natalie; Eriksen, Bjørn Odvar; Dubourg, Laurence; Vidal-Petiot, Emmanuelle; Grubb, Anders; Hansson, Magnus; Lamb, Edmund J.; Littmann, Karin; Mariat, Christophe; Melsom, Toralf; Schaeffner, Elke; Sundin, Per-Ola; Åkesson, Anna; Larsson, Anders; Cavalier, Etienne; Bukabau, Justine B.; Sumaili, Ernest K.; Yayo, Eric; Monnet, Dagui; Flamant, Martin; Nyman, Ulf; Delanaye, Pierre (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-26)
      BACKGROUND - The accuracy of estimation of kidney function with the use of routine metabolic tests, such as measurement of the serum creatinine level, has been controversial. The European Kidney Function Consortium (EKFC) developed a creatinine-based equation (EKFC eGFRcr) to estimate the glomerular filtration rate (GFR) with a rescaled serum creatinine level (i.e., the serum creatinine level is ...

    • Data on the relation between renal biomarkers and measured glomerular filtration rate 

      Pottel, Hans; Dubourg, Laurence; Schaeffner, Elke; Eriksen, Bjørn Odvar; Melsom, Toralf; Lamb, Edmund J.; Rule, Andrew D.; Turner, Stephen T; Glassock, Richard J.; De Souza, Vandrea; Selistre, Luciano; Goffin, Karolien; Pauwels, Steven; Mariat, Christophe; Flamant, Martin; Bevc, Sebastjan; Delanaye, Pierre; Ebert, Natalie (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10)
      The data presented in this article are related to the research article entitled “The Diagnostic Value of Rescaled Renal Biomarkers Serum Creatinine and Serum Cystatin C and their Relation with Measured Glomerular Filtration Rate” (Pottel et al. (2017) [1]). Data are presented demonstrating the rationale for the normalization or rescaling of serum cystatin C, equivalent to the rescaling of serum ...

    • GFR in healthy aging: An individual participant data meta-analysis of iohexol clearance in european population-based cohorts 

      Eriksen, Bjørn Odvar; Pálsson, Runólfur; Ebert, Natalie; Melsom, Toralf; van der Giet, Markus; Gudnason, Vilmundur; Indridasson, Olafur S.; Inker, Lesley A.; Jenssen, Trond Geir; Levey, Andrew S.; Solbu, Marit Dahl; Tighiouart, Hocine; Schaeffner, Elke (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07)
      <i>Background</i> - Population mean GFR is lower in older age, but it is unknown whether healthy aging is associated with preserved rather than lower GFR in some individuals.<br><br> <i>Methods</i> - We investigated the cross-sectional association between measured GFR, age, and health in persons aged 50–97 years in the general population through a meta-analysis of iohexol clearance measurements ...

    • Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP 

      Matsushita, Kunihiro; Kaptoge, Stephen; Hageman, Steven H J; Sang, Yingying; Ballew, Shoshana H.; Grams, Morgan E.; Surapaneni, Aditya; Sun, Luanluan; Arnlov, Johan; Bozic, Milica; Brenner, Hermann; Brunskill, Nigel J.; Chang, Alex R.; Chinnadurai, Rajkumar; Cirillo, Massimo; Correa, Adolfo; Ebert, Natalie; Eckardt, Kai-Uwe; Gansevoort, Ron T.; Gutierrez, Orlando; Hadaegh, Farzad; He, Jiang; Hwang, Shih-Jen; Jafar, Tazeen H.; Jassal, Simerjot K.; Kayama, Takamasa; Kovesdy, Csaba P.; Landman, Gijs W.; Levey, Andrew S.; Lloyd-Jones, Donald M.; Major, Rupert W.; Miura, Katsuyuki; Muntner, Paul; Nadkarni, Girish N.; Nowak, Christoph; Ohkubo, Takayoshi; Pena, Michelle J.; Polkinghorne, Kevan R.; Sairenchi, Toshimi; Schaeffner, Elke; Schneider, Markus P.; Shalev, Varda; Shlipak, Michael G.; Solbu, Marit Dahl; Stempniewicz, Nikita; Tollitt, James; Valdivielso, José M; van der Leeuw, Joep; Wang, Angela Yee-Moon; Wen, Chi-Pang; Woodward, Mark; Yamagishi, Kazumasa; Yatsuya, Hiroshi; Zhang, Luxia; Dorresteijn, Jannick A N; Di Angelantonio, Emanuele; Visseren, Frank L J; Pennells, Lisa; Coresh, Josef (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-16)
      Aims - The 2021 European Society of Cardiology (ESC) guideline on cardiovascular disease (CVD) prevention categorizes moderate and severe chronic kidney disease (CKD) as high and very-high CVD risk status regardless of other factors like age and does not include estimated glomerular filtration rate (eGFR) and albuminuria in its algorithms, systemic coronary risk estimation 2 (SCORE2) and systemic ...

    • Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets 

      Matsushita, K; Jassal, Simerjot; Solbu, Marit Dahl; Sang, Yingying; Ballew, Shoshana H.; Grams, Morgan E.; Surapaneni, Aditya; Arnlov, Johan; Bansal, Nisha; Bozic, Milica; Brenner, Hermann; Brunskill, Nigel J.; Chang, Alex R.; Chinnadurai, Rajkumar; Cirillo, Massimo; Correa, Adolfo; Ebert, Natalie; Eckardt, Kai-Uwe; Gansevoort, Ron T.; Gutierrez, Orlando; Hadaegh, Farzad; He, Jiang; Hwang, Shih-Jen; Jafar, Tazeen H.; Kayama, Takamasa; Kovesdy, Csaba P.; Landman, Gijs W.; Levey, Andrew S.; Lloyd-Jones, Donald M.; Major, Rupert W.; Miura, Katsuyuki; Muntner, Paul; Nadkarni, Girish N.; Naimark, David M.J.; Nowak, Christoph; Ohkubo, Takayoshi; Pena, Michelle J.; Polkinghorne, Kevan R.; Sabanayagam, Charumathi; Sairenchi, Toshimi; Schneider, Markus P.; Shalev, Varda; Shlipak, Michael; Stempniewicz, Nikita; Tollitt, James; Valdivielso, José M.; van der Leeuw, Joep; Wang, Angela Yee-Moon; Wen, Chi-Pang; Woodward, Mark; Yatsuya, Hiroshi; Zhang, Luxia; Schaeffner, Elke; Coresh, Josef (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-04)
      Background: Chronic kidney disease (CKD) measures (estimated glomerular filtration rate [eGFR] and albuminuria) are frequently assessed in clinical practice and improve the prediction of incident cardiovascular disease (CVD), yet most major clinical guidelines do not have a standardized approach for incorporating these measures into CVD risk prediction. “CKD Patch” is a validated method to calibrate ...

    • Iohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 2: Why to measure glomerular filtration rate with iohexol? 

      Delanaye, Pierre; Melsom, Toralf; Ebert, Natalie; Bäck, Sten-Erik; Mariat, Christophe; Cavalier, Etienne; Björk, Jonas; Christensson, Anders; Nyman, Ulf; Porrini, Esteban; Remuzzi, Giuseppe; Ruggenenti, Piero; Schaeffner, Elke; Soveri, Inga; Sterner, Gunnar; Eriksen, Bjørn Odvar; Gasperi, Flavia (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-09)
      A reliable assessment of glomerular filtration rate (GFR) is of paramount importance in clinical practice as well as epidemiological and clinical research settings. It is recommended by Kidney Disease: Improving Global Outcomes guidelines in specific populations (anorectic, cirrhotic, obese, renal and non-renal transplant patients) where estimation equations are unreliable. Measured GFR is the ...

    • Iohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 1: How to measure glomerular filtration rate with iohexol? 

      Delanaye, Pierre; Ebert, Natalie; Melsom, Toralf; Gasperi, Flavia; Mariat, Christophe; Cavalier, Etienne; Björk, Jonas; Christensson, Anders; Nyman, Ulf; Porrini, Esteban; Remuzzi, Giuseppe; Ruggenenti, Piero; Schaeffner, Elke; Soveri, Inga; Sterner, Gunnar; Eriksen, Bjørn Odvar; Bäck, Sten-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-08-23)
      While there is general agreement on the necessity tomeasure glomerular filtration rate (GFR) inmany clinical situations, there is less agreement on the bestmethod to achieve this purpose.As the gold standardmethod for GFR determination, urinary (or renal) clearance of inulin, fades into the background due to inconvenience and high cost, a diversity of filtrationmarkers and protocols compete to ...

    • Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa 

      Delanaye, Pierre; Vidal-Petiot, Emmanuelle; Björk, Jonas; Ebert, Natalie; Eriksen, Bjørn Odvar; Dubourg, Laurence; Grubb, Anders; Hansson, Magnus; Littmann, Karin; Mariat, Christophe; Melsom, Toralf; Schaeffner, Elke; Sundin, Per-Ola; Bökenkamp, Arend; Berg, Ulla B.; Åsling-Monemi, Kajsa; Åkesson, Anna; Larsson, Anders; Cavalier, Etienne; Dalton, R Neil; Courbebaisse, Marie; Couzi, Lionel; Gaillard, Francois; Garrouste, Cyril; Jacquemont, Lola; Kamar, Nassim; Legendre, Christophe; Rostaing, Lionel; Stehlé, Thomas; Haymann, Jean-Philippe; Selistre, Luciano da Silva; Strogoff-de-Matos, Jorge P.; Bukabau, Justine B.; Sumaili, Ernest K.; Yayo, Eric; Monnet, Dagui; Nyman, Ulf; Pottel, Hans; Flamant, Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-24)
      Background - A new Chronic Kidney Disease Epidemiology Collaboration equation without the race variable has been recently proposed (CKD-EPIAS). This equation has neither been validated outside USA nor compared with the new European Kidney Function Consortium (EKFC) and Lund-Malmö Revised (LMREV) equations, developed in European cohorts.<p> <p>Methods - Standardized creatinine and measured glomerular ...

    • Performance of creatinine-based equations to estimate glomerular filtration rate with a methodology adapted to the context of drug dosage adjustment 

      Delanaye, Pierre; Björk, Jonas; Courbebaisse, Marie; Couzi, Lionel; Ebert, Natalie; Eriksen, Bjørn Odvar; Dalton, R. Neil; Dubourg, Laurence; Melsom, Toralf; Nyman, Ulf (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-28)
      <p><i>Aim:</i> The Cockcroft-Gault (CG) creatinine-based equation is still used to estimate glomerular filtration rate (eGFR) for drug dosage adjustment. Incorrect eGFR may lead to hazardous over- or underdosing. <p><i>Methods:</i> In a cross-sectional analysis, CG was validated against measured GFR (mGFR) in 14 804 participants and compared with the Modification-of-Diet-in-Renal-Diseases (MDRD), ...

    • Prospects for improved glomerular filtration rate estimation based on creatinine-results from a transnational multicentre study 

      Bjõrk, Jonas; Nyman, Ulf; Courbebaisse, Marie; Couzi, Lionel; Dalton, R. Neil; Dubourg, Laurence; Ebert, Natalie; Eriksen, Bjõrn O.; Gaillard, Francois; Garrouste, Cyril; Grubb, Anders; Hansson, Magnus; Jacquemont1, Lola; Jones, Ian; Kamar, Nassim; Lamb, Edmund J.; Legendre, Christophe; Littmann, Karin; Mariat, Christophe; Melsom, Toralf; Rostaing, Lionel; Rule, Andrew D.; Schaeffner, Elke; Sundin, Per-Ola; Turner, Stephen; Åkesson, Anna; Delanaye, Pierre; Pottel, Hans (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-13)
      Background - The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine equation is routinely used to assess renal function but exhibits varying accuracy depending on patient characteristics and clinical presentation. The overall aim of the present study was to assess if and to what extent glomerular filtration rate (GFR) estimation based on creatinine can be improved.<p> <p>Methods ...