Blar i forfatter Det helsevitenskapelige fakultet "Pala, Valeria"

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    • Alcohol consumption and risk of urothelial cell bladder cancer in the European prospective investigation into cancer and nutrition cohort 

      Botteri, Edoardo; Ferrari, Pietro; Roswall, Nina; Tjønneland, Anne; Hjartåker, Anette; Huerta, José María; Fortner, Renée Turzanski; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Pala, Valeria; Pérez-Cornago, Aurora; Sonestedt, Emily; Liedberg, Fredrik; Overvad, Kim; Sánchez, María-José; Gram, Inger Torhild; Stepien, Magdalena; Trijsburg, Laura; Ljungberg, Börje; Johansson, Mikael B.; Kühn, Tilman; Panico, Salvatore; Tumino, Rosario; Bueno-De-Mesquita, Hendrik Bastiaan; Weiderpass, Elisabete (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-31)
      Findings on the association between alcohol consumption and bladder cancer are inconsistent. We investigated that association in the European Prospective Investigation into Cancer and Nutrition cohort. We included 476,160 individuals mostly aged 35-70 years, enrolled in ten countries and followed for 13.9 years on average. Hazard ratios (HR) for developing urothelial cell carcinoma (UCC; 1,802 ...

    • Altered plasma metabolite levels can be detected years before a glioma diagnosis 

      Löding, Sebastian; Andersson, Ulrika; Kaaks, Rudolf; Schulze, Matthias B.; Pala, Valeria; Urbarova, Ilona Halva; Amiano, Pilar; Colorado-Yohar, Sandra M.; Guevara, Marcela; Heath, Alicia K.; Chatziioannou, Anastasia Chrysovalantou; Johansson, Mattias; Nyberg, Lars Erik; Antti, Henrik; Björkblom, Benny; Melin, Beatrice (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-31)
      Genetic and metabolic changes in tissue and blood are reported to occur several years before glioma diagnosis. Since gliomas are currently detected late, a liquid biopsy for early detection could affect the quality of life and prognosis of patients. Here, we present a nested case-control study of 550 prediagnostic glioma cases and 550 healthy controls from the Northern Sweden Health and Disease ...

    • Anthropometric and reproductive factors and risk of esophageal and gastric cancer by subtype and subsite: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort 

      Sanikini, Harinakshi; Muller, David C.; Sophiea, Marisa; Rinaldi, Sabina; Agudo, Antonio; Duell, Eric J.; Weiderpass, Elisabete; Overvad, Kim; Tjønneland, Anne; Halkjær, Jytte; Boutron-Ruault, Marie-Christine; Carbonnel, Franck; Cervenka, Iris; Boeing, Heiner; Kaaks, Rudolf; Kühn, Tilman; Trichopoulou, Antonia; Martimianaki, Georgia; Karakatsani, Anna; Pala, Valeria; Palli, Domenico; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Skeie, Guri; Rylander, Charlotta; López, María-Dolores Chirlaque; Sánchez, Maria-Jose; Ardanaz, Eva; Regnér, Sara; Stocks, Tanja; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Aune, Dagfinn; Tong, Tammy Y.N.; Kliemann, Nathalie; Murphy, Neil; Chadeau-Hyam, Marc; Gunter, Mark J.; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-03)
      Obesity has been associated with upper gastrointestinal cancers; however, there are limited prospective data on associations by subtype/subsite. Obesity can impact hormonal factors, which have been hypothesized to play a role in these cancers. We investigated anthropometric and reproductive factors in relation to esophageal and gastric cancer by subtype and subsite for 476,160 participants from the ...

    • Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors 

      Robinson, Natassia; Casement, John; Gunter, Marc J.; Huybrechts, Inge; Agudo, Antonio; Barranco, Miguel Rodríguez; Eichelmann, Fabian; Johnson, Theron; Kaaks, Rudolf; Pala, Valeria; Panico, Salvatore; Sandanger, Torkjel M; Schultze, Matthias B.; Travis, Ruth C.; Tumino, Rosario; Vineis, Paolo; Weiderpass, Elisabete; Skinner, Roderick; Sharp, Linda; McKay, Jill A; Strathdee, Gordon (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-30)
      BACKGROUND: Childhood cancer survivors (CCS) exhibit significantly increased chronic diseases and premature death. Abnormalities in DNA methylation are associated with development of chronic diseases and reduced life expectancy. We investigated the hypothesis that anti-cancer treatments are associated with long-term DNA methylation changes that could be key drivers of adverse late health ...

    • The association between adult attained height and sitting height with mortality in the European prospective investigation into cancer and nutrition (EPIC) 

      Sawada, Norie; Wark, Petra A.; Merritt, Melissa A.; Tsugane, Shoichiro; Ward, Heather A.; Rinaldi, Sabina; Weiderpass, Elisabete; Dartois, Laureen; His, Mathilde; Boutron-Ruault, Marie-Christine; Turzanski-Fortner, Renée; Kaaks, Rudolf; Overvad, Kim; Redondo, María-Luisa; Travier, Noemie; Molina-Portillo, Elena; Dorronsoro, Miren; Cirera, Lluis; Ardanaz, Eva; Perez-Cornago, Aurora; Trichopoulou, Antonia; Lagiou, Pagona; Valanou, Elissavet; Masala, Giovanna; Pala, Valeria; Peeters, Petra H.M.; van der Schouw, Yvonne T.; Melander, Olle; Manjer, Jonas; da Silva, Marisa Eleonor; Skeie, Guri; Tjønneland, Anne; Olsen, Anja; Gunter, Mark J.; Riboli, Elio; Cross, Amanda J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-03)
      Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly ...

    • Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study 

      Sen, Abhijit; Tsilidis, Konstantinos K.; Allen, Naomi E.; Rinaldi, Sabina; Appleby, Paul N.; Almquist, Martin; Schmidt, Julie A.; Dahm, Christina C.; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha L.; Clavel-Chapelon, Françoise; Baglietto, Laura; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katze, Verena A.; Boeing, Heiner; Trichopoulou, Antonia; Tsironis, Christos; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Hjartåker, Anette; Lund, Eiliv; Weiderpass, Elisabete; Quirós, J. Ramón; Agudo, Antonio; Sánchez, Mariá-José; Arriola, Larraitz; Gavrila, Diana; Gurrea, Aurelio Barricarte; Tosovic, Ada; Hennings, Joakim; Sandström, Maria; Romieu, Isabelle; Ferrari, Pietro; Zamora-Ros, Raul; Khaw, Kay-Tee; Wareham, Nicholas J.; Riboli, Elio; Gunter, Marc; Franceschi, Silvia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-27)
      Background: Results from several cohort and case–control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered.<p> <p>Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid carcinoma ...

    • Baseline and lifetime alcohol consumption and risk of skin cancer in the European Prospective Investigation into Cancer and Nutrition cohort (EPIC) 

      Mahamat-Saleh, Yahya; Al-Rahmoun, Marie; Severi, Gianluca; Ghiasvand, Reza; Veierød, Marit Bragelien; Caini, Saverio; Palli, Domenico; Botteri, Edoardo; Sacerdote, Carlotta; Ricceri, Fulvio; Lukic, Marko; Sánchez, Maria J.; Pala, Valeria; Tumino, Rosario; Chiodini, Paolo; Amiano, Pilar; Colorado-Yohar, Sandra; Chirlaque, María-Dolores; Ardanaz, Eva; Bonet, Catalina; Katzke, Verena; Kaaks, Rudolf; Schulze, Matthias B.; Overvad, Kim; Dahm, Christina C.; Antoniussen, Christian S.; Tjønneland, Anne; Kyrø, Cecilie; Bueno-de-Mesquita, Bas; Manjer, Jonas; Jansson, Malin; Esberg, Anders; Mori, Nagisa; Ferrari, Pietro; Weiderpass, Elisabete; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-19)
      Experimental evidence suggests that alcohol induces cutaneous carcinogenesis, yet epidemiological studies on the link between alcohol intake and skin cancer have been inconsistent. The European Prospective Investigation into Cancer and Nutrition (EPIC) is a prospective cohort initiated in 1992 in 10 European countries. Alcohol intake at baseline and average lifetime alcohol intake were assessed using ...

    • Blood polyphenol concentrations and differentiated thyroid carcinoma in women from the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Zamora-Ros, Raul; Lujan-Barroso, Leila; Achaintre, David; Franceschi, Silvia; Kyrø, Cecilie; Overvad, Kim; Tjønneland, Anne; Truong, Therese; Lecuyer, Lucie; Boutron-Ruault, Marie Christine; Katzke, Verena; Johnson, Theron S.; Schulze, Matthias B; Trichopoulou, Antonia; Peppa, Eleni; La Vechia, Carlo; Masala, Giovanna; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Ricceri, Fulvio; Skeie, Guri; Ramón Quirós, J; Rodriguez-Barranco, Miguel; Amiano, Pilar; Chirlaque, María Dolores; Ardanaz, Eva; Almquist, Martin; Hennings, Joakim; Vermeulen, Roel; Wareham, Nicholas J; Tong, Tammy Y.N.; Aune, Dagfinn; Byrnes, Graham; Weiderpass, Elisabete; Scalbert, Augustin; Rinaldi, Sabina; Agudo, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-06)
      <p>Background - Polyphenols are natural compounds with anticarcinogenic properties in cellular and animal models, but epidemiological evidence determining the associations of these compounds with thyroid cancer (TC) is lacking. <p>Objectives - The aim of this study was to evaluate the relations between blood concentrations of 36 polyphenols and TC risk in EPIC (the European Prospective Investigation ...

    • Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study 

      Sedlmeier, Anja M.; Viallon, Vivian; Ferrari, Pietro; Peruchet-Noray, Laia; Fontvieille, Emma; Amadou, Amina; Seyed Khoei, Nazlisadat; Weber, Andrea; Baurecht, Hansjörg; Heath, Alicia K.; Tsilidis, Kostas; Kaaks, Rudolf; Katzke, Verena; Inan-Eroglu, Elif; Schulze, Matthias B.; Overvad, Kim; Bonet, Catalina; Ubago-Guisado, Esther; Chirlaque, María-Dolores; Ardanaz, Eva; Perez-Cornago, Aurora; Pala, Valeria; Tumino, Rosario; Sacerdote, Carlotta; Pasanisi, Fabrizio; Borch, Kristin Benjaminsen; Rylander, Charlotta; Weiderpass, Elisabete; Gunter, Marc J.; Fervers, Béatrice; Leitzmann, Michael F.; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-02)
      Background - Classical anthropometric traits may fail to fully represent the relationship of weight, adiposity, and height with cancer risk. We investigated the associations of body shape phenotypes with the risk of overall and site-specific cancers.<p> <p>Methods - We derived four distinct body shape phenotypes from principal component (PC) analysis on height, weight, body mass index (BMI), waist ...

    • Breast cancer risk after recent childbirth: A pooled analysis of 15 prospective studies 

      Nichols, Hazel B.; Schoemaker, Minouk J.; Cai, Jianwen; Xu, Jiawei; Wright, Lauren B.; Brook, Mark N.; Jones, Michael E.; Adami, Hans Olov; Baglietto, Laura; Bertrand, Kimberly A.; Blot, William J.; Boutron-Ruault, Marie-Christine; Dorronsoro, Miren; Dossus, Laure; Eliassen, A. Heather; Giles, Graham G.; Gram, Inger Torhild; Hankinson, Susan E.; Hoffman-Bolton, Judy; Kaaks, Rudolf; Key, Timothy J.; Kitahara, Cari M.; Larsson, Susanna C.; Linet, Martha; Merritt, Melissa A.; Milne, Roger L.; Pala, Valeria; Palmer, Julie R.; Peeters, Petra H.; Riboli, Elio; Sund, Malin; Tamimi, Rulla M.; Tjønneland, Anne; Trichopoulou, Antonia; Ursin, Giske; Vatten, Lars Johan; Visvanathan, Kala; Weiderpass, Elisabete; Wolk, Alicja; Zheng, Wei; Weinberg, Clarice R.; Swerdlow, Anthony J.; Sandler, Dale P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-01)
      <i>Background</i>: Parity is widely recognized as protective for breast cancer, but breast cancer risk may be increased shortly after childbirth. Whether this risk varies with breastfeeding, family history of breast cancer, or specific tumor subtype has rarely been evaluated.<p> <p><i>Objective</i>: To characterize breast cancer risk in relation to recent childbirth.<p> <p>Design</i> : Pooled ...

    • Circulating Isovalerylcarnitine and Lung Cancer Risk: Evidence from Mendelian Randomization and Prediagnostic Blood Measurements 

      Smith-Byrne, Karl; Cerani, Agustin; Guida, Florence; Zhou, Sirui; Agudo, Antonio; Aleksandrova, Krasimira; Barricarte, Aurelio; Barranco, Miguel Rodríguez; Bochers, Christoph H.; Gram, Inger Torhild; Han, Jun; Amos, Christopher I.; Hung, Rayjean J.; Grankvist, Kjell; Nøst, Therese Haugdahl; Imaz, Liher; Chirlaque-López, María Dolores; Johansson, Mikael; Kaaks, Rudolf; Kühn, Tilman; Martin, Richard M.; McKay, James D.; Pala, Valeria; Robbins, Hilary A.; Sandanger, Torkjel M; Schibli, David; Schulze, Matthias B.; Travis, Ruth C.; Vineis, Paolo; Weiderpass, Elisabete; Brennan, Paul; Johansson, Mattias; Richards, J Brent (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-04)
      Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies.<p> <p>Materials and Methods: We used Mendelian randomization (MR) to screen 207 metabolites for their role in lung cancer predisposition using independent genome-wide association studies (GWAS) of blood ...

    • Circulating RANKL and RANKL/OPG and breast cancer risk by ER and PR subtype: Results from the EPIC cohort. 

      Sarink, Danja; Schock, Helena; Johnson, Theron; Overvad, Kim; Holm, Marianne; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; His, Mathilde; Kvaskoff, Marina; Boeing, Heiner; Lagiou, Pagona; Papatesta, Eleni-Maria; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Bueno-De-Mesquita, Hendrik Bastiaan; van Gils, Carla H.; Peeters, Petra H.; Weiderpass, Elisabete; Agudo, Antonio; Sánchez, María-José; Chirlaque, Maria-Dolores; Ardanaz, Eva; Amiano, Pilar; Khaw, Kay Tee; Travis, Ruth; Dossus, Laure; Gunter, Mark; Rinaldi, Sabina; Merritt, Melissa; Riboli, Elio; Kaaks, Rudolf; Fortner, Renée T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-31)
      Receptor activator of nuclear factor-kappa B (RANK)-RANK ligand (RANKL) signaling promotes mammary tumor development in experimental models. Circulating concentrations of soluble RANKL (sRANKL) may influence breast cancer risk via activation of RANK signaling; this may be modulated by osteoprotegerin (OPG), the decoy receptor for RANKL. sRANKL and breast cancer risk by hormone receptor subtype has ...

    • Comparison of abdominal adiposity and overall obesity in relation to risk of small intestinal cancer in a European Prospective Cohort 

      Lu, Yunxia; Cross, Amanda J; Murphy, Neil; Freisling, Heinz; Travis, Ruth C; Ferrari, Pietro; Katzke, Verena A; Kaaks, Rudolf; Olsson, Åsa; Johansson, Ingegerd; Renström, Frida; Panico, Salvatore; Pala, Valeria; Palli, Domenico; Tumino, Rosario; Peeters, Petra H; Siersema, Peter D; Bueno-De-Mesquita, HB; Trichopoulou, Antonia; Klinaki, Eleni; Tsironis, Christos; Agudo, Antonio; Navarro, Camen; Sanchez, Maria-Jose; Barricarte, Aurelio; Boutron-Ruault, Marie-Christine; Fagherazzi, Guy; Racine, Antoine; Weiderpass, Elisabete; Gunter, Marc J; Riboli, Eilo (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-13)
      Background: The etiology of small intestinal cancer (SIC) is largely unknown, and there are very few epidemiological studies published to date. No studies have investigated abdominal adiposity in relation to SIC. <p>Methods: We investigated overall obesity and abdominal adiposity in relation to SIC in the European Prospective Investigation into Cancer and Nutrition (EPIC), a large prospective ...

    • Comparison of prognostic models to predict the occurrence of colorectal cancer in asymptomatic individuals: A systematic literature review and external validation in the EPIC and UK Biobank prospective cohort studies 

      Smith, Todd; Muller, David C.; Moons, Karel G.M.; Cross, Amanda J.; Johansson, Mattias; Ferrari, Pietro; Fagherazzi, Guy; Peeters, Petra H. M.; Severi, Gianluca; Hüsing, Anika; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Bonet, Catalina; Rodríguez-Barranco, Miguel; Huerta, Jose Maria; Gurrea, Aurelio Barricarte; Bradbury, Kathryn Erica; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; Palli, Domenico; Pala, Valeria; Vineis, Paolo; Bueno-De-Mesquita, Bas; Ohlsson, Bodil; Harlid, Sophia; Van Guelpen, Bethany; Skeie, Guri; Weiderpass, Elisabete; Jenab, Mazda; Murphy, Neil; Riboli, Eilo; Gunter, Marc J.; Aleksandrova, Krasimira Jekova; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-03)
      <i>Objective</i> - To systematically identify and validate published colorectal cancer risk prediction models that do not require invasive testing in two large population-based prospective cohorts.<p><p> <i>Design</i> - Models were identified through an update of a published systematic review and validated in the European Prospective Investigation into Cancer and Nutrition (EPIC) and the UK ...

    • Consumption of dairy products and colorectal cancer in the European prospective investigation into cancer and nutrition (EPIC) 

      Murphy, Neil; Norat, Teresa; Ferrari, Pietro; Jenab, Mazda; Bueno-de-Mesquita, Bas; Skeie, Guri; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Boutron-Ruault, Marie Christine; Clavel-Chapelon, Françoise; Nailler, Laura; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Peeters, Petra H.M.; Dik, Vincent K.; Weiderpass, Elisabete; Lund, Eiliv; Garcia, José Ramon Quiros; Zamora-Ros, Raul; Pérez, Maria José Sánches; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Manjer, Jonas; Almquist, Martin; Johansson, Ingegerd; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Crowe, Francesca L.; Fedirko, Veronika; Gunter, Mark J.; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of total dairy products, total milk and dietary calcium. However, less is known about whether the inverse associations vary for individual dairy products with differing fat contents. Materials and Methods: In the European Prospective Investigation into Cancer and Nutrition (EPIC), ...

    • Determinants of non- response to a second assessment of lifestyle factors and body weight in the EPIC-PANACEA study 

      May, Anne M.; Adema, Lotte E.; Romaguera, Dora; Vergnaud, Anne-Claire; Agudo, Antonio; Ekelund, Ulf; Steffen, Annika; Orfanos, Philippos; Slimani, Nadia; Rinaldi, Sabina; Mouw, Traci; Rohrmann, Sabine; Hermann, Silke; Boeing, Heiner; Bergmann, Manuela M.; Jakobsen, Marianne Uhre; Overvad, Kim; Wareham, Nicholas J.; Gonzalez, Carlos; Tjonneland, Anne; Halkjaer, Jytte; Key, Timothy J.; Spencer, Elizabeth A.; Hellström, Veronica; Manjer, Jonas; Hedblad, Bo; Lund, Eiliv; Braaten, Tonje; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie Christine; Rodriguez, Laudina; Sanchez, Maria Jose; Dorronsoro, Miren; Barricarte, Aurelio; Huerta, Jose Maria; Naska, Androniki; Trichopoulou, Antonia; Palli, Domenico; Pala, Valeria; Norat, Teresa; Mattiello, Amalia; Tumino, Rosario; van der Daphne, A.; Bueno-de-Mesquita, H. Bas; Riboli, Elio; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      This paper discusses whether baseline demographic, socio-economic, health variables, length of follow-up and method of contacting the participants predict non-response to the invitation for a second assessment of lifestyle factors and body weight in the European multi-center EPIC-PANACEA study. Over 500.000 participants from several centers in ten European countries recruited between 1992 and 2000 ...

    • Dietary Fibre Intake and Risks of Cancers of the Colon and Rectum in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Norat, Teresa; Ferrari, Pietro; Jenab, Mazda; Bueno-de-Mesquita, H. Bas; Skeie, Guri; Dahm, Christina C.; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie Christine; Racine, Antoine; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Siersema, Peter D.; van Duijnhoven, Fränzel J.B.; Peeters, Petra H M; Hjartåker, Anette; Engeset, Dagrun; Gonzalez, Carlos A.; Sánchez, Maria-José; Dorronsoro, Miren; Navarro, Camen; Ardanaz, Eva; Quirós, José R.; Sonestedt, Emily; Ericson, Ulrika; Nilsson, Lena; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Crowe, Francesca L.; Fedirko, Veronika; Wark, Petra A.; Chuang, Shu-Chun; Riboli, Eilo (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Earlier analyses within the EPIC study showed that dietary fibre intake was inversely associated with colorectal cancer risk, but results from some large cohort studies do not support this finding. We explored whether the association remained after longer follow-up with a near threefold increase in colorectal cancer cases, and if the association varied by gender and tumour location. After a mean ...

    • Dietary folate intake and pancreatic cancer risk: Results from the European prospective investigation into cancer and nutrition 

      Park, Jin Young; Bueno-de-Mesquita, Hendrik Bastiaan; Ferrari, Pietro; Weiderpass, Elisabete; de Batlle, Jordi; Tjønneland, Anne; Kyrø, Cecilie; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Kritikou, Maria; Masala, Giovanna; Pala, Valeria; Tumino, Rosario; Panico, Salvatore; Peeters, Petra H.; Skeie, Guri; Merino, Susana; Duell, Eric J.; Rodríguez-Barranco, Miguel; Dorronsoro, Miren; Chirlaque, Maria-Dolores; Ardanaz, Eva; Gylling, Björn; Schneede, Jørn; Ericson, Ulrika; Sternby, Hanna; Khaw, Kay-Tee; Bradbury, Kathryn E.; Huybrechts, Inge; Aune, Dagfinn; Vineis, Paolo; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-04)
      Pancreatic cancer (PC) has an exceptionally low survival rate and primary prevention strategies are limited. Folate plays an important role in one‐carbon metabolism and has been associated with the risk of several cancers, but not consistently with PC risk. We aimed to investigate the association between dietary folate intake and PC risk, using the standardised folate database across 10 European ...

    • Dietary intake of trans fatty acids and breast cancer risk in 9 European countries 

      Matta, Michèle; Huybrechts, Inge; Biessy, Carine; Casagrande, Corinne; Yammine, Sahar; Fournier, Agnès; Olsen, Karina Standahl; Lukic, Marco; Gram, Inger Torhild; Ardanaz, Eva; Sánchez, Maria-José; Dossus, Laure; Fortner, Renée T.; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B.; Amiano, Pilar; Agudo, Antonio; Colorado-Yohar, Sandra; Guirós, J. Ramón; Tumino, Rosario; Panico, Salvatore; Masala, Giovanna; Pala, Valeria; Sacerdote, Carlotta; Tjønneland, Anne; Olsen, Anja; Dahm, Christina C.; Rosendahl, Ann H.; Borgquist, Signe; Wennberg, Maria; Heath, Alicia K.; Aune, Dagfinn; Schmidt, Julie; Weiderpass, Elisabete; Chajes, Veronique; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-30)
      Background - Trans fatty acids (TFAs) have been hypothesised to influence breast cancer risk. However, relatively few prospective studies have examined this relationship, and well-powered analyses according to hormone receptor-defined molecular subtypes, menopausal status, and body size have rarely been conducted.<p> <p>Methods - In the European Prospective Investigation into Cancer and Nutrition ...

    • Healthy lifestyle and the risk of pancreatic cancer in the EPIC study 

      Naudin, Sabine; Viallon, Vivian; Hashim, Dana; Freisling, Heinz; Jenab, Mazda; Weiderpass, Elisabete; Perrier, Flavie; McKenzie, Fiona; Bueno-de-Mesquita, Hendrik Bastiaan; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Mancini, Francesca R.; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kaaks, Rudolf; Bergmann, Manuela; Boeing, Heiner; Peppa, Eleni; Karakatsani, Anna; Trichopoulou, Antonia; Pala, Valeria; Masala, Giovana; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; May, Anne M.; van Gils, Carla H.; Rylander, Charlotta; Borch, Kristin Benjaminsen; Chirlaque López, María Dolores; Sánchez, Mariá-José; Ardanaz, Eva; Quirós, José Ramón; Amiano Exezarreta, Pilar; Sund, Malin; Drake, Isabel; Regnér, Sara; Travis, Ruth C.; Wareham, Nick; Aune, Dagfinn; Riboli, Elio; Gunter, Marc J.; Duell, Eric J.; Brennan, Paul; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-28)
      Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association between the Healthy Lifestyle Index (HLI) and PC risk was examined. Within the European Prospective Investigation into Cancer and Nutrition cohort, 1113 incident PC (57% women) ...