• Gut Microbiome Associates With Lipid-Lowering Effect of Rosuvastatin in Vivo 

      Liu, Yinhui; Song, Xiaobo; Zhou, Huimin; Zhou, Xue; Xia, Yunlong; Dong, Xin; Zhong, Wei; Tang, Shaoying; Wang, Lili; Wen, Shu; Xiao, Jing; Tang, Li (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-22)
      Background: Statin has been widely used to treat hyperlipidemia because of its high potency in decreasing cholesterol levels. The present study aimed to examine the lipid-lowering effect of rosuvastatin and the composition, diversity and species abundance of gut microbiome in association with rosuvastatin efficacy. <br> <br> TRIAL REGISTRATION: ChiCTR-ORC-17013212 at the First Affiliated Hospital ...
    • Microbiome Structure and Mucosal Morphology of Jejunum Appendix and Colon of Rats in Health and Dysbiosis 

      Shao, Chenyi; Song, Xiaobo; Wang, Lili; Zhang, Hongying; Liu, Yinhui; Wang, Chunhao; Chen, Shenmin; Ren, Baowei; Wen, Shu; Xiao, Jing; Tang, Li (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-06)
      Gut microbiota contributes to human health. Plenty of studies demonstrate that antibiotics can disrupt gut ecosystem leading to dysbiosis. Little is known about the microbial variation of appendix and its up/downstream intestine after antibiotic treatment. This study aimed to investigate the microbiome and mucosal morphology of jejunum, appendix, and colon of rats in health and dysbiosis. A rodent ...