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    • Dynamics of the IL-33/ST2 network in the progression of human colorectal adenoma to sporadic colorectal cancer 

      Guanglin, Cui; Qi, Haili; Gundersen, Mona Dixon; Yang, Hang; Christiansen, Ingrid B; Sørbye, Sveinung Wergeland; Goll, Rasmus; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-10-17)
      Most sporadic colorectal cancers (CRCs) develop from preformed adenomas. Cytokines are involved in the transition from adenoma to CRC. Interleukin-33 (IL-33) is a newly discovered proinflammatory cytokine belonging to the IL-1 cytokine family and involved in the development of chronic inflammation and cancer. The aim of this study was to evaluate the dynamics of the IL-33/ST2 axis during the sequence ...