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Left atrial diameter, left ventricle filling indices, and association with all-cause mortality: Results from the population-based Tromsø Study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-28)
<p><i>Aims</i>: To examine the associations between diastolic dysfunction indices and long‐term risk of all‐cause mortality in adults over 23‐year follow‐up.</p>
<p><i>Methods and results</i>: Participants (n = 2734) of the population‐based Tromsø Study of Norway had echocardiography in 1994–1995. Of these 67% were repeated in 2001 and/or 2007–2008. Mortality between 1994 and 2016 was determined ...
Repeated measurements of carotid atherosclerosis and future risk of venous thromboembolism: the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-05)
<p><i>Background</i>: Whether a relationship between atherosclerosis and subsequent venous thromboembolism (VTE) exists is controversial.</p>
<p><i>Objective</i>: To investigate the association between carotid atherosclerosis and VTE by using repeated measurements of intima media thickness (IMT) and total plaque area (TPA) in participants recruited from the general population.</p>
<p><i>Methods</i>: ...
The independent and joint associations of physical activity and body mass index with myocardial infarction: The Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-13)
Physical activity and overweight are associated with myocardial infarction (MI). However, their joint association
with MI remains unclear. Our objective was to examine the independent and joint association between leisuretime
physical activity (LTPA), body mass index (BMI) and MI. This prospective cohort study included 16,572
men and women (47.5% women) aged 20–54 years who took part in the second ...
Myocardial infarction and future risk of cancer in the general population—the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-07)
The association between myocardial infarction (MI) and future risk of incident cancer is scarcely investigated. Therefore, we aimed to study the risk of cancer after a first time MI in a large cohort recruited from a general population. Participants in a large population-based study without a previous history of MI or cancer (n = 28,763) were included and followed from baseline to date of cancer, ...
Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-16)
Background:<br>Vitamin D deficiency may be a risk factor for mortality but previous meta-analyses lacked standardization of laboratory methods for 25-hydroxyvitamin D (25[OH]D) concentrations and used aggregate data instead of individual participant data (IPD). We therefore performed an IPD meta-analysis on the association between standardized serum 25(OH)D and mortality.<br>Methods:<br>In a European ...
Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-12)
<p><i>Background - </i>Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease.
<p><i>Methods - </i>We did a combined analysis of ...
Treatment target achievement after myocardial infarction and ischemic stroke: cardiovascular risk factors, medication use and lifestyle – The Tromsø Study 2015-2016. Secondary prevention in myocardial infarction and stroke
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-29)
Aims - To investigate European guideline treatment target achievement in cardiovascular risk factors, medication use, and lifestyle, after myocardial infarction (MI) or ischaemic stroke, in women and men living in Norway.<p>
<p>Methods and results - In the population-based Tromsø Study 2015–16 (attendance 65%), 904 participants had previous validated MI and/or stroke. Cross-sectionally, we ...
Use of repeated blood pressure and cholesterol measurements to improve cardiovascular disease risk prediction: an individual-participant-data meta-analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-13)
The added value of incorporating information from repeated blood pressure and cholesterol measurements to
predict cardiovascular disease (CVD) risk has not been rigorously assessed. We used data on 191,445 adults from
the Emerging Risk Factors Collaboration (38 cohorts from 17 countries with data encompassing 1962–2014) with
more than 1 million measurements of systolic blood pressure, total ...
Atrial fibrillation, venous thromboembolism, ischemic stroke, and all-cause mortality: The Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-06)
Background
Atrial fibrillation (AF) is associated with increased risk of ischemic stroke and all‐cause mortality. Patients with AF are also at increased risk of venous thromboembolism (VTE), but information on how AF impacts VTE‐related mortality is scarce.
Objectives - To investigate the impact of AF on all‐cause mortality in subjects with and without a thromboembolic event (VTE or ischemic ...
Is the ongoing obesity epidemic partly explained by concurrent decline in cigarette smoking? Insights from a longitudinal population study. The Tromsø Study 1994–2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-23)
<p>The increase of obesity coincides with a substantial decrease in cigarette smoking. We assessed post-cessation weight change and its contribution to the obesity epidemic in a general population in Norway. A total of 14,453 participants (52.6% women), aged 25–54 years in 1994, who attended at least two of four surveys in the Tromsø Study between 1994 and 2016, were included in the analysis. Hereof ...