Det helsevitenskapelige fakultet: Nye registreringer
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A histological study of the protracted dismantling of the spent (Sertoli-only) shark spermatocyst post-spermiation: Insight from species with or without testis-associated lymphomyeloid tissue
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-27)Sertoli cells of sharks are non-permanent components of the spermatocyst that they share exclusively with only one germ cell stage. After spermiation, all Sertoli cells, and thus the whole spent cyst, are disposed of in an area adjacent to the spermatozoal spermatocysts, that is, the resorption zone (RZ). Differences in the histology and magnitude of the RZ of the mature blue shark and Greenland ... -
The outcomes of team-based learning versus small group interactive learning in the obstetrics and gynecology course for undergraduate students
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-17)Introduction - Team-based learning (TBL) is a well-established active teaching method which has been shown to have pedagogical advantages in some areas such as business education and preclinical disciplines in undergraduate medical education. Increasingly, it has been adapted to clinical disciplines. However, its superiority over conventional learning methods used in clinical years of medical school ... -
FilmArray (BCID2) provides essential and timely results in bloodstream infections in small acute care hospitals without conventional microbiology services
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-12)We have evaluated the performance of FilmArray BCID2 in reactive blood cultures in a small acute care hospital compared to conventional diagnostics at a regional microbiological laboratory. This is a retrospective observational study of BactAlert reactive blood cultures (n = 160) from Helgeland Hospital, July–December 2021, analysed by BCID2 locally and conventional culture at a regional laboratory. ... -
Joint effect of ischemic stroke and obesity on the risk of venous thromboembolism: the Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-27)Background: Patients with ischemic stroke have increased risk of venous thromboembolism (VTE). Obesity is prevalent in stroke patients and a well-established risk factor for VTE. Whether obesity further increases the VTE risk in patients with stroke remains unclear.<p> <p>Objectives: We investigated the joint effect of ischemic stroke and obesity on the risk of incident VTE in a population-based ... -
Major depression mistaken as frontotemporal dementia due to PET scan
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-02)Frontotemporal dementia (FTD) is associated with progressive degeneration of the frontal lobes and this leads to changes in language, motor symptoms, behavior and executive functions.1 In an early stage, patients with FTD usually have intact memory functions.2 40% of the cases of FTD are misdiagnosed,3 with delayed diagnosis compared to other dementias.4 Differentiating FTD from other psychiatric ... -
Would you like to be a general practitioner? Baseline findings of a longitudinal survey among Danish medical trainees
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-05)Background Recruiting and securing primary care physician workforce has been the center of international attention for decades. In Denmark, the number of general practitioners has decreased by 8.5% since 2013. However, a rising population age and increasing prevalence of chronic diseases and multimorbidity place an even greater future need for general practitioners in Denmark. The choice of ... -
Traditional Chinese medicine for post-viral olfactory dysfunction: A systematic review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-25)Background: Post-viral olfactory dysfunction (PVOD) is the common symptoms of long COVID, lacking of effective treatments. Traditional Chinese medicine (TCM) is claimed to be effective in treating olfactory dysfunction, but the evidence has not yet been critically appraised. We conducted a systematic review to evaluate the effectiveness and safety of TCM for PVOD. Methods: We searched eight ... -
The sexual and reproductive healthcare challenges when dealing with female migrants and refugees in low and middle-income countries (a qualitative evidence synthesis)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-19)Background Migrants and refugees face unprecedented inequalities in accessing sexual and reproductive health (SRH) in developed and developing countries. Most attention has focused on the rich world perspective, while there are huge numbers of migrants and refugees moving towards less developed countries. This article synthesizes the barriers to proper SRH care from low and middle-income ... -
Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-11)There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when compar ing interventions and their clinical value. The aim of this systematic review was to summarize and evaluate endpoints used to assess appetite and dietary intake in cancer cachexia clinical trials. A search for studies published from 1 January 1990 until 2 June 2021 was conducted ... -
Treatment and prevention of neonatal sepsis
(Doctoral thesis; Doktorgradsavhandling, 2024-09-20)Worldwide, the incidence of neonatal sepsis is estimated at around 3000 cases per 100,000 live births, accompanied by a mortality rate of 17.6%. Group B streptococcus (GBS) is globally the leading cause of newborn infections. The global burden of neonatal sepsis and invasive GBS disease is skewed towards the low-income countries, but the outcome of invasive GBS disease with massive inflammation can ... -
Adhesion mechanisms and bacteriocins in Staphylococcus haemolyticus - New targets for the prevention and treatment of infections
(Doctoral thesis; Doktorgradsavhandling, 2024-09-13)<i>Staphylococcus haemolyticus</i> er ein bakterie med mange eigenskapar. Han finst naturleg i mikrobiotaen vår, men kan også vere opportunistisk patogen. Evna til å danne biofilm, unngå immunsystemet og motstå antibiotikabehandling gjer at behandling er utfordrande. Målet med avhandlinga var å utvide forståinga av virulensfaktorar og bakteriosinproduksjon hos bakterien for å finne betre måtar å ... -
An evidence map on traditional medicine across health outcomes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-25)Background - Traditional medicine (TM) plays a significant role in healthcare either as part of the primary healthcare system or as an adjunct to conventional medicine. This study aimed to map systematic reviews (SRs) of TM modalities across health conditions and identify gaps in the research literature to facilitate priority setting in future TM research.<p> <p>Methods - We searched 17 databases ... -
Comparisons of assessment pathways after abnormal mammography screening in Denmark, Norway, and Spain
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-29)Purpose - To ensure high-quality screening programmes and effective utilization of resources, it is important to monitor how cancer detection is affected by different strategies performed at recall assessment. This study aimed to describe procedures performed at recall assessment and compare and evaluate the performance of the assessment in Denmark, Norway, and Spain in terms of screen-detected ... -
Unlocking the Transformative Potential of Outdoor Office Work—A Constructivist Grounded Theory Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-09)White-collar workers around the world are reconfiguring their ways of working. Some have found their way out, performing office work outdoors, through walk-and-talks, outdoor meetings, or reading sessions. Working outdoors has proved both invigorating and challenging. This qualitative interview study aims to develop a conceptual framework concerning the implications of white-collar workers incorporating ... -
Exploring the dynamics of situational interest in team-based learning in undergraduate medical education
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-30)Background Team-based learning (TBL) is a widely recognized instructional approach in medical education blending direct instruction with active-cooperative learning in small groups. While TBL is known to enhance knowledge acquisition, its impact on student motivation, particularly through situational interest, remains underexplored. This study aimed to investigate the development of situational ... -
Plasma Concentration of 36 (Poly)phenols and Prospective Body Weight Change in Participants from the EPIC Cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-01-25)Introduction: Dietary intake of (poly)phenols has been linked to reduced adiposity and body weight (BW) in several epidemiological studies. However, epidemiological evidence on (poly)phenol biomarkers, particularly plasma concentrations, is scarce. We aimed to investigate the associations between plasma (poly)phenols and prospective BW change in participants from the European Prospective Investigation ... -
On the use of the healthy lifestyle index to investigate specific disease outcomes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-07-15)The healthy lifestyle index (HLI), defined as the unweighted sum of individual lifestyle components, was used to investigate the combined role of lifestyle factors on health-related outcomes. We introduced weighted outcome-specific versions of the HLI, where individual lifestyle components were weighted according to their associations with disease outcomes. Within the European Prospective Investigation ... -
Does the association between adiposity measures and pre-frailty among older adults vary by social position? Findings from the Tromsø study 2015/2016
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-31)Introduction - Pre-frailty provides an ideal opportunity to prevent physical frailty and promote healthy ageing. Excess adiposity has been associated with an increased risk of pre-frailty, but limited studies have explored whether the association between adiposity measures and pre-frailty varies by social position.<p> <p>Methods - We used data from the seventh survey of the Tromsø Study (Tromsø7) ... -
Parental reports of hospital- and community-based follow-up services, self-efficacy, and symptoms of depression a few months after discharge of a prematurely born child
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-06-19)Background - Video streaming in emergency medical communication centers (EMCC) from caller to medical dispatcher has recently been introduced in some countries. Death by trauma is a leading cause of death and injuries are a frequent reason to contact EMCC. We aimed to investigate if video streaming is associated with recognition of a need for first aid during calls regarding injured patients and ... -
Can video streaming improve first aid for injured patients? A prospective observational study from Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-28)Background - Video streaming in emergency medical communication centers (EMCC) from caller to medical dispatcher has recently been introduced in some countries. Death by trauma is a leading cause of death and injuries are a frequent reason to contact EMCC. We aimed to investigate if video streaming is associated with recognition of a need for first aid during calls regarding injured patients and ...