Blar i forfatter Doktorgradsavhandlinger (Helsefak) "Engesland, André"
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In vitro permeation models for healthy and compromised skin: The Phospholipid Vesicle-based Permeation Assay (PVPA) for skin applications
Engesland, André (Doctoral thesis; Doktorgradsavhandling, 2015-03-20)In vitro models with the ability to estimate drug penetration through healthy and compromised skin may reduce animal testing of drugs and cosmetics to a minimum. The phospholipid vesicle based permeation assay (PVPA) is based on a tight barrier composed of liposomes mimicking cells. It was originally made to mimic the intestinal epithelial barrier and in this project further developed to mimic the ...