Browsing Doktorgradsavhandlinger (Helsefak) by Author "Kloos, Julia Maria"
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Horizontal transfer, selection and maintenance of antibiotic resistance determinants
Kloos, Julia Maria (Doctoral thesis; Doktorgradsavhandling, 2021-06-11)Scientific abstract Antibiotic resistance, especially in Gram-negative pathogens, represents a substantial clinical and financial burden to our society. The presented work investigated mechanisms and evolutionary dynamics that promote the emergence and maintenance of resistance in bacteria. In the first study, conserved collateral susceptibility changes were identified across resistant uropathogenic ...