• Mechanism and structural requirements for formation of p62 bodies and degradation of p62 by selective autophagy 

      Palara, Anthimi (Doctoral thesis; Doktorgradsavhandling, 2021-12-03)
      Selective autophagy is responsible for the lysosomal degradation of damaged and surplus cytoplasmic components, including misfolded proteins and dysfunctional organelles. Selective autophagy is required for protein and organelle quality control basally and upon stress. For the autophagic process to be precise, selective autophagy receptors (SARs) like SQSTM1/p62 are required. Autophagic substrates ...