<i>Summary</i> - Extensive evidence support an association between arterial cardiovascular disease (CVD, i.e. myocardial infarction [MI] and ischemic stroke), and subsequent venous thromboembolism (VTE, i.e. deep vein thrombosis [DVT]) and pulmonary emboli [PE]). However, the mechanism behind the associations remains unclear. The aim of this thesis was to investigate the impact of ischemic stroke ...

<p><i>Background and aims - </i>Much research has been conducted on age-related changes in cognitive function, but psychomotor abilities, such as manual dexterity, have been less studied. A better understanding is needed of which movement components account for the general slowing of performance and how central factors, such as cognitive decline, contribute to slowing. The aims of this thesis were ...

The main objective of this thesis was to systematically review potential side effects of antibiotic therapy in neonates and to study the gut microbiota composition of preterm infants receiving probiotic prophylaxis. This thesis includes two systemic reviews, a prospective longitudinal multi-centre trial investigating the gut microbiota in preterm infants receiving probiotics compared to preterm ...

The thesis is based upon data from two cross-sectional population-based surveys, the SAMINOR 1 Survey (2003-2004) and the SAMINOR 2 Clinical Survey (2012-2014). The prevalence of pre-diabetes and diabetes mellitus among Sami and non-Sami inhabitants of the 24 municipalities from North- and Mid-Norway was estimated in the SAMINOR 1 Survey. No statistically significant difference in the prevalence of ...

Supervision of non-professionals has become an integrated part of current practice in pediatric physiotherapy in primary health care. Limited knowledge exists regarding the content, organization and achievements of such practice. In this doctoral project, we explored supervision in the field of physiotherapy services for preschool children with CP who have personal aides responsible for the daily ...

Patient harms, or adverse events which is the term used in this PhD thesis, is a global health problem. The Global Trigger Tool (GTT) is a widely used method to identify and measure adverse events (AEs). The method involves reviewers searching for triggers (situations) in randomly selected medical records and subsequently identifying AEs. However, the method is criticized due to the time used by ...

Background: Alzheimer’s disease (AD) may develop 10-15 years before onset of mild cognitive impairment (MCI). Early intervention may serve to halt or delay disease progression. Thus, there is a need to investigate early cognitive and biological markers to detect and track disease progression. Subjective cognitive decline (SCD) is an established risk-factor for AD. However, SCD is a common phenomenon ...

Venous thromboembolism (VTE) is a common disease with serious short- and long-term complications. VTE is a collective term for deep vein thrombosis (DVT) and pulmonary embolism (PE) and is the third most common cardiovascular disease, causing significant morbidity and mortality. Despite preventive strategies, the incidence of VTE has been stable or increasing slightly during the last decades, affecting ...

Traditional healing practices used when faced with illness or crisis, exist in many North Norwegian communities. Northern Troms has a historical multi-ethnicity of Sami, Kven and Norwegian. The notion of culture appears ambivalent and ambiguous, particularly concerning the Sami identity, but cultural diversity is nevertheless manifested through the use of traditional healing practices such as reading. ...

<p><i>Background:</i> Dental caries and periodontal diseases are the most common oral diseases, affecting millions of people worldwide. These diseases are highly preventable; therefore any measures that promote oral health (OH) should be implemented at the community and individual level. Although programmes designed to prevent OH problems often focus on children, young adults aged 18-25 years are ...