Doktorgradsavhandlinger (Helsefak): Nye registreringer
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Some issues on provision and access to dental services in Norway
(Doctoral thesis; Doktorgradsavhandling, 2009-12-04)The organisation and financing of the Norwegian oral health care differ compared to general health care. The public responsibility for general health care includes the whole population, and the scope is universal coverage involving public finance, and historically public provision as well. Concerning oral health care, there seems to be less emphasis on providing the same level of service to all ... -
Material wealth and subjective well-being
(Doctoral thesis; Doktorgradsavhandling, 2009-10-07)People have long argued over the relation of income and material well-being to happiness. A variety of studies have examined the happiness of those living at the lowest economic levels as well as those living in relatively affluent nations. Taken together, this body of research suggests that income is correlated with subjective well-being (SWB), but is neither the most important factor in happiness, ... -
Helicobacter pylori and dyspepsia from a public health perspective : The Sørreisa Gastrointestinal Disorder Study
(Doctoral thesis; Doktorgradsavhandling, 2009-04-24)Dyspepsia is a highly prevalent condition, involving substantial health-care resources. Ever since Marshall and Warren in 1984 discovered that Helicobacter pylori could cause peptic ulcer, it has been discussed to what extend Helicobacter pylori play a role in dyspepsia in general. In 2004 a population based survey was carried out in the municipality of Sørreisa, comprising a questionnaire survey ... -
Diagnosis of cancer in general practice : a study of delay problems and warning signals of cancer, with implications for public cancer information and for cancerdiagnostic strategies in general practice
(Doctoral thesis; Doktorgradsavhandling, 1991-01-26)Early diagnosis of cancer is beneficial to most cancer patients. This doctoral thesis is based on studies in general practice in Tromsø, Norway, during the years 1978-1985. General practitioners have a very important role in the work excluding or leading up to a cancer diagnosis. The studies deal with diagnostic delay, the value of symptoms, and with strategies for GP s to improve their cancer ... -
A population based study on coronary heart disease in families : the Finnmark Study 1974-1989
(Doctoral thesis; Doktorgradsavhandling, 2000) -
Fetal cardiac output and its distribution to the placenta and brain at 11-20 weeks of gestation
(Doctoral thesis; Doktorgradsavhandling, 2009-09-11)Objective: To study some aspects of fetal heart structure and function using ultrasonography at 11-20 weeks of gestation with an emphasis on the distribution of cardiac output to the placenta and upper body including brain. <br> Methods: In a cross-sectional study of unselected pregnant population, the structure of the fetal heart was studied using transvaginal ultrasonography and feasibility ... -
Consumption of antibacterial agents : pharmacoepidemiology, resistance and interventions
(Doctoral thesis; Doktorgradsavhandling, 2009-09-03)Det overordnede målet med prosjektene som inngår i avhandlingen har vært å bidra til mer kunnskap om rasjonell bruk av antibiotika. Prosjektene er gjennomførte i allmennpraksis, og i sykehus i henholdsvis Norge, Danmark, Island og Sverige. <br>Det første delprosjektet undersøkte vi om det var mulig å endre forskrivning av antibiotika ved akutt mellomørebetennelse hos barn som kom til en legevakt. ... -
Size characterisation of liposomes using asymmetrical flow field-flow fractionation : factors influencing fractionation and size determination
(Doctoral thesis; Doktorgradsavhandling, 2009-08-27)Liposomes play an important role in medical and pharmaceutical science as e.g. nanoscale drug carriers. One of their most important features is their size and size distribution, influencing both their biodistribution and passive targeting abilities upon intravenous administration. To this day there is no single method for size characterisation of liposomes that fulfils all following criteria: being ... -
A genetic spectrum approach to affective and schizophrenic disorders : a twin- and family study
(Doctoral thesis; Doktorgradsavhandling, 2009-09-15)Over 300 eneggete- og toeggete tvillingpar rekruttert fra sykehusarkiv, og deres 1.grads slektninger (foreldre og søsken), ble intervjuet personlig og diagnostisert i henhold til moderne diagnostiske systemer (DSM-III-R) både med hensyn til symptomforstyrrelser (Akse I), og personlighetsforstyrrelser (Akse II). De ble også intervjuet angående forhold knyttet til tvillingenes fødsel og oppvekst. ... -
Psychological factors in the recovery of coronary artery disease patients in Northern Norway
(Doctoral thesis; Doktorgradsavhandling, 2009-06-05)The thesis comprises four studies of psychosocial factors associated with the recovery of patients following Coronary Artery Bypass Graft (CABG) surgery and Percutaneous Coronary Intervention (PCI) treatment in Northern Norway. Paper I describes an interview study of nine patients following CABG surgery. The patients reported extensive use of avoidant (e.g. neglecting symptoms, avoiding thoughts ... -
Gene expression profile of normal and compromised placentas
(Doctoral thesis; Doktorgradsavhandling, 2009-06-26)<b>Objective</b> <br>Placenta has an important function of sustaining life in utero. Role of placental gene expression in the physiology of parturition and pathogenesis of pregnancy disorders are poorly understood. The aims of this thesis were to: <br>1. Investigate the effect of labor on global gene expression profile of normal placentas <br>2. Compare placental gene expression profile of ... -
Frail homebound elderly: basic nursing challenges of home care : a comparative study across 11 sites in Europe
(Doctoral thesis; Doktorgradsavhandling, 2009-02-12)The overall purpose of this thesis is to describe, analyse, and compare characteristics of the basic needs (nutrition and elimination) and clinical features of the elderly receiving home care. Data are derived from the Aged in Home Care (AD-HOC) project, a cross-sectional population-based study at 11 urban sites in Europe (2001/2003), using Resident Assessment Instrument for Home Care. During data ... -
Smerter under nordlyset : den vanlige lidelsen. Det uvanlige livet : fortellinger fra hverdagslivet med langvarige smerter
(Doctoral thesis; Doktorgradsavhandling, 2009-04-28)Studien baserer seg på 20 voksne personers fortellinger om det å leve med langvarige, ikke maligne smerter. Informantene hadde hatt smerter fra tre til over tretti år, var henvist til en smertepoliklinikk i Nord Norge for videre utredning. Studien har fokus på hvordan livet med langvarige smerter kan arte seg for enkeltmennesker. Funnene viser at smertene etablerte seg som langvarige på en gradvis ... -
Cardiovascular risk factors and pulmonary function in long-term survivors of testicular cancer
(Doctoral thesis; Doktorgradsavhandling, 2009-04-24)Testikkelkreft er den vanligste kreftformen blant unge menn, og >95 % blir i dag helbredet av sykdommen. Dermed er kunnskap om mulige seneffekter etter behandlingen viktig. <br>Avhandlingen ”Cardiovascular risk factors and pulmonary function in long-term survivors of testicular cancer” ble forsvart for graden ph.d 24. april 2009. Takket være effektiv cytostatikabehandling som ble tatt i bruk på ... -
Molecular analysis of angiogenic markers as prognostic factors for non-small cell lung cancer (NSCLC)
(Doctoral thesis; Doktorgradsavhandling, 2009-03-20)Nydannelse av blodkar er avgjørende for at en kreftsvulst skal etablere seg og vokse og et viktig angrepspunkt for ny kreftbehandling. Arbeidet undersøker molekyler som er viktig for reguleringen av blodkardannelse i kreftsvulster og hvordan disse påvirker overlevelsesprognosen for lungekreftpasienter. <br>Avhandlingens tittel er ”Molecular analysis of angiogenic markers as prognostic factors for ... -
Waiting for nursing home placement: a study of the life situation of frail elderly and their carers
(Doctoral thesis; Doktorgradsavhandling, 2009-01-30)Den forventede levealderen har økt nesten over hele verden. Dette har ført til at antall eldre stiger raskt, og veksten er ventet å fortsette. I Norge vokser gruppen eldre over 80 år raskest. Det er gjennomført mye internasjonal forskning om eldre og det å være deres pårørende. Fokus i denne studien var eldre som ventet på sykehjemsplass i en nordnorsk kommune, og deres pårørende. Det ble ikke ... -
Internet-based patient communication
(Doctoral thesis; Doktorgradsavhandling, 2009-05-22)<b>Objective</b> <br>To investigate some of the consequences that electronic health communication has for patients, health professionals and society at large. The underlying studies investigate reasons patients provide for using online communication solutions, the current propagation and pace of Internet health communication, and whether such services would replace conventional health communication ... -
Advanced Non-small Cell Lung Cancer Effects of Chemotherapy and Impact on Health Related Quality of Life
(Doctoral thesis; Doktorgradsavhandling, 2009-03-13)Avhandlingen presenterer behandlingseffekt, bivirkninger og livskvalitet hos lungekreftpasienter som får moderne cellegiftbehandling. Pasientene med performance status (PS) 2 er etterpå vurdert separat. <br><br>Avhandlingens tittel er ”Advanced non-small cell Lung Cancer – Effects of Chemotherapy and Impact on Health Related Quality of Life”. Den ble forsvart for graden PhD 13.03.2009. På verdensbasis ... -
Effectiveness of interventions and factors of relevance in the treatment of children with conduct problems
(Doctoral thesis; Doktorgradsavhandling, 2008-12-17)The principal aim of this dissertation was to study the effectiveness of treatment of children for severe conduct problems, and to explore factors of relevance for the effects of treatment on these children. In three studies, 127 children aged 4‐8 years and their families participated in a randomized controlled trial of the Incredible Years training sessions that were implemented in two outpatient ... -
Treatment of obesity and type 2 diabetes with PPARα agonists – effects on myocardial metabolism, gene expression and ventricular function
(Doctoral thesis; Doktorgradsavhandling, 2009-01-16)Hos diabetikere fører mangel på insulin og/eller nedsatt følsomhet for insulin i vevene til at konsentrasjonen av glukose og fettsyrer i blodet stiger til svært høye verdier. Det diabetiske hjertet kan bare i svært liten grad nyttiggjøre seg glukose, og energiproduksjonen tilpasses derfor forbrenning av fettsyrer. Opptaket av fettsyrer kan imidlertid bli høyere enn forbrenningen, slik at det over ...