• Echocardiographic reference ranges in older children and adolescents in sub-Saharan Africa 

      Majonga, Edith D.; Rehman, Andrea M.; McHugh, Grace; Mujuru, Hilda A.; Nathoo, Kusum; Patel, Mohammad S.; Munyati, Shungu; Odland, Jon Øyvind; Kranzer, Katharina; Kaski, Juan P.; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-30)
      Background: Echocardiographic reference ranges are important to identify abnormalities of cardiac dimensions. Reference ranges for children in sub-Saharan Africa have not been established. The aim of this study was to establish echocardiographic z-score references for Black children in sub-Saharan Africa.<p> <p>Methods: 282 healthy subjects aged 6–16 years (143 [51%] males) with no known history ...
    • Effect of patient-delivered household contact tracing and prevention for tuberculosis: A household cluster-randomised trial in Malawi 

      Kaswaswa, Kruger; MacPherson, Peter; Kumwenda, Moses; Mpunga, James; Thindwa, Deus; Nliwasa, Marriott; Mwapasa, Mphatso; Odland, Jon Øyvind; Tomoka, Tamiwe; Chipungu, Geoffrey; Mukaka, Mavuto; Corbett, Elizabeth L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-08)
      <p><b> Background</b> Household contact tracing provides TB screening and TB preventive therapy (TPT) to contacts at high risk of TB disease. However, it is resource intensive, inconvenient, and often poorly implemented. We investigated a novel model aiming to improve uptake. <p><b> Methods</b> Between May and December 2014, we randomised patient with TB who consented to participate in the ...
    • Exhaled nitric oxide is associated with inflammatory biomarkers and risk of acute respiratory exacerbations in children with HIV-associated chronic lung disease 

      Flygel, Trym Thune; Hameiri-Bowen, Dan; Simms, Victoria; Rowland-Jones, Sarah; Ferrand, Rashida Abbas; Bandason, Tsitsi; Yindom, Louis-Marie; Odland, Jon Øyvind; Cavanagh, Jorunn Pauline; Flægstad, Trond; Sovershaeva, Evgeniya (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-07)
      Objectives: Chronic lung disease is a recognized complication in children with HIV. Acute respiratory exacerbations (ARE) are common among this group and cause significant morbidity. Exhaled nitric oxide (eNO) is a known marker of local airway inflammation. We investigated the association between eNO and ARE, biomarkers of systemic inflammation, and the effect of azithromycin on eNO levels.<p> ...