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dc.contributor.authorForsdahl, Signe Helene
dc.contributor.authorSolberg, Steinar
dc.contributor.authorSingh, Kulbir
dc.contributor.authorJacobsen, Bjarne Koster
dc.date.accessioned2013-12-16T09:39:17Z
dc.date.available2013-12-16T09:39:17Z
dc.date.issued2010
dc.description.abstractBackground: In a population-based study in Tromsø, Norway, the authors assessed whether an abdominal aortic aneurysm (AAA) or the maximal infrarenal aortic diameter in a non-aneurismal aorta influence total and cardiovascular disease (CVD) mortality. Methods: A total of 6640 men and women, aged 25–84 years, were included in a 10-year mortality follow-up: 345 subjects with a diagnosed AAA and 6295 subjects with a non-aneurismal aorta. Non-aneurismal aortic diameter and prevalent AAAs were categorized into seven groups. Results: In subjects without an AAA, an aortic diameter 30 mm increased age- and sex-adjusted total mortality [mortality rate ratio (MRR) = 3.73, 95% confidence interval (CI) 1.77–7.89] and CVD mortality (MRR = 9.24, 95% CI 4.07–20.97) compared with subjects with aortic diameter of 21–23 mm. An AAA at screening was strongly associated with deaths from aortic aneurysm and was associated with total (MRR = 1.60, 95% CI 1.31–1.96) and CVD mortality (MRR = 2.41, 95% CI 1.81–3.21). This was not explained by deaths due to an AAA. Adjustments for CVD risk factors could fully explain the increased total, but not CVD mortality in subjects with an AAA. Conclusions: An AAA increases total and CVD mortality. In the large majority of subjects with a non-aneurysmal aorta, the diameter does not influence total or CVD mortality. However, in individuals with a maximal diameter >26 mm (2% of the population), a positive relationship is founden
dc.identifier.citationInternational Journal of Epidemiology 39(2010) nr. 1 s. 225-232en
dc.identifier.cristinIDFRIDAID 344516
dc.identifier.doihttp://dx.doi.org/10.1093/ije/dyp320
dc.identifier.issn0300-5771
dc.identifier.urihttps://hdl.handle.net/10037/5639
dc.identifier.urnURN:NBN:no-uit_munin_5333
dc.language.isoengen
dc.publisherOxford University Pressen
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Cardiology: 771en
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Kardiologi: 771en
dc.titleAbdominal aortic aneurysms, or a relatively large diameter of non-aneurysmal aortas, increase total and cardiovascular mortality: the Tromsø study.en
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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