In transition metal-mediated carboxylation reactions, CO₂ inserts into a metal–nucleophile bond. At the carboxylation transition state (TS), CO₂ may interact with the metal (<i>inner</i>-sphere path) or may insert without being activated by the metal (<i>outer</i>-sphere path). Currently, there is no consensus as to which path prevails. In order to establish general predictions ...

The question of ligand noninnocence in Cu corroles has long been a topic of discussion. Presented herein is a Cu K-edge X-ray absorption spectroscopy (XAS) study, which provides a direct probe of the metal oxidation state, of three Cu corroles, Cu[TPC], Cu[Br8TPC], and Cu[(CF3)8TPC] (TPC = meso-triphenylcorrole), and the analogous Cu(II) porphyrins, Cu[TPP], Cu[Br8TPP], and Cu[(CF3)8TPP] (TPP = ...

The Lomfjorden Fault Zone in the eastern part of Spitsbergen is one of the prominent structures in Svalbard oriented parallel to the continental margin of the Barents Shelf. It consists of a network of three N–S-striking major faults (Veteranen, Lomfjorden, and Agardhbukta faults), two N–S-striking reverse faults (Lomfjella and Bjørnfjellet reverse faults), and a number of NE–SW- and NNW–SSE-striking ...

The main goal of the EDMON (Electronic Disease Monitoring Network) project is to detect the spread of contagious diseases at the earliest possible moment, and potentially before people know that they have been infected. The results shall be visualized on real-time maps as well as presented in digital communication. In this paper, a hybrid of K-nearness Neighbor (KNN) and cumulative sum (CUSUM), known ...

DNA ligases operating at low temperatures have potential advantages for use in biotechnological applications. For this reason, we have characterized the temperature optima and thermal stabilities of three minimal Lig E-type ATP-dependent DNA ligase originating from Gram-negative obligate psychrophilic bacteria. The three ligases, denoted Vib-Lig, Psy-Lig, and Par-Lig, show a remarkable range of ...

Knowledge acquisition is the prime objective of a learner from an educational system and evaluating the learner's knowledge is the eventual goal of an examination process. This paper introduces a system which is able to produce fill‐in‐the‐blank questions to test the knowledge of a learner that he or she has accumulated after reading a course material. The question generation task is subdivided into ...

Predicting the effect of single-point mutations on protein stability or protein−ligand binding is a major challenge in computational biology. Free energy calculations constitute the most rigorous approach to this problem, though the estimation of converged values for amino acid mutations remains challenging. To overcome this limitation, we developed tailored protocols to calculate free energy ...

This study was carried out with a view of understanding the temporal dynamics of microcystin concentrations in both algal seston and water samples and the associated public health risk. All the major MC variants, namely MC-LR, MC-YR, and MC-RR, were detected in both the algal seston and water samples. In the majority of the samples, the most potent variant, MC-LR, constituted the greatest proportion ...

Data driven networks applicable for shipping industrial applications to create decentralized system intelligence are considered in this study. Such system intelligence can facilitate to improve the respective operational efficiency in local (i.e. vessel operations) and global (i.e. logistics operations) scales in shipping as the main advantage. The main features of these data driven networks are ...

To investigate the heavy metal pollution in leachate from sanitary landfill site of municipal solid waste, a survey was conducted in Tromsø, Northern Norway. Results shows that contents of heavy metals in landfill leachate follow the order Mn>Zn>Ni>Cu>Cr>As>Pb>Cd>Hg, and the order of the risk of different heavy metals is: Mn>Ni>As>Zn>Cr>Pb>Cd>Hg>Cu. The concentrations of Mn and Ni in landfill leachate ...