To meet the availability target and reduce system downtime, effective maintenance have a great importance. However, maintenance performance is greatly affected in complex ways by human factors. Hence, to have an effective maintenance operation, these factors needs to be assessed and quantified. To avoid the inadequacies of traditional human error assessment (HEA) approaches, the application of ...

In this study we present a method to estimate neutral thermospheric densities using ISR-observations following a sequence of high-frequency radio wave ionospheric heating modi cations in the vicinity of the ionosphere peak density altitude (hmF2), and the results from two different days of observations with low geomagnetic activity levels (AP<4) that are compared to the MSIS model. Slight ...

The memory properties in paleoclimate temperature records based on model simulations and proxy-reconstructions have been investigated, to find out if these records exhibit long-range memory in a similar manner as many instrumental temperature records. On time scales from years to centuries and even millennia, long-range memory is identified in the paleoclimate records using a toolbox of statistical ...

Terror er ikke et nytt fenomen i Europa. Likevel har terrorfokuset økt som et resultat av en rekke alarmerende hendelser de siste tiårene. Etter terrorangrepene mot USA 11. september 2001 fikk den vestlige verden for alvor opp øynene for hvordan terrorangrep kan bli utført på den internasjonale arena. Som følger av terrortrusselen utviklet FNs sjøfartsorganisasjon, IMO, ISPS-koden. Koden stiller ...

Targeted inhibition of the oncogenic BCR-ABL1 fusion protein using the ABL1 tyrosine kinase inhibitor imatinib has become standard therapy for chronic myelogenous leukemia (CML), with most patients reaching total and durable remission. However, a significant fraction of patients develop resistance, commonly due to mutated ABL1 kinase domains. This motivated development of second-generation drugs ...

Precise knowledge about the extent of the West Antarctic Ice Sheet (WAIS) at the Last Glacial Maximum (LGM; c. 26.5–19 cal. ka BP) is important in order to 1) improve paleo-ice sheet reconstructions, 2) provide a robust empirical framework for calibrating paleo-ice sheet models, and 3) locate potential shelf refugia for Antarctic benthos during the last glacial period. However, reliable reconstructions ...

We present a high-resolution record of calcium carbonate preservation alongside the distribution pattern of planktic foraminifera from the Fram Strait. The record covers the marine isotope stage (MIS) 2, 28.8 to 15.4 kyr, including the Last Glacial Maximum (LGM) and the early deglaciation in multidecadal temporal resolution. The investigation is based on the distribution patterns of planktic ...

With an aging patient population and increasing complexity in patient disease trajectories, physicians are often met with complex patient histories from which clinical decisions must be made. Due to the increasing rate of adverse events and hospitals facing financial penalties for readmission, there has never been a greater need to enforce evidence-led medical decision-making using available ...

The climate of the last glaciation circa 65,000–25,000 years ago was interrupted by about 15 abrupt temperature fluctuations, the so-called Dansgaard-Oeschger events consisting of warm interstadials and cold stadials recorded in Greenland ice cores. The largest fluctuations occur in the North Atlantic region, but they have been registered over the most of the world. The events are linked to changes ...

The climate of the last glaciation was interrupted by numerous abrupt temperature fluctuations, referred to as Greenland interstadials and stadials. During warm interstadials the meridional overturning circulation was active transferring heat to the north, whereas during cold stadials the Nordic Seas were ice-covered and the overturning circulation was disrupted. Meltwater discharge, from ice sheets ...