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norskBrowsing Artikler, rapporter og annet (medisinsk biologi) by Issue Date
Now showing items 41-60 of 1054
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Halibut mitochondrial genomes contain extensive heteroplasmic tandem repeat arrays involved in DNA recombination
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-01-11)Background: Halibuts are commercially important flatfish species confined to the North Pacific and North Atlantic Oceans. We have determined the complete mitochondrial genome sequences of four specimens each of Atlantic halibut (Hippoglossus hippoglossus), Pacific halibut (Hippoglossus stenolepis) and Greenland halibut (Reinhardtius hippoglossoides), and assessed the nucleotide variability within ... -
Hormone replacement therapy use and plasma levels of sex hormones in the Norwegian Women and Cancer Postgenome Cohort : a cross-sectional analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-02-14)Background: Hormone replacement therapy use (HRT) is associated with increased breast cancer risk. Our primary objective was to explore hormone levels in plasma according to HRT use, body mass index (BMI) and menopausal status. A secondary objective was to validate self-reported questionnaire information on menstruation and HRT use in the Norwegian Women and Cancer postgenome cohort (NOWAC). Methods: ... -
Vasopressin impairs brain, heart and kidney perfusion: an experimental study in pigs after transient myocardial ischemia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-02-21)Introduction: Arginine vasopressin (AVP) is increasingly used to restore mean arterial pressure (MAP) in low-pressure shock states unresponsive to conventional inotropes. This is potentially deleterious since AVP is also known to reduce cardiac output by increasing vascular resistance. The effects of AVP on blood flow to vital organs and cardiac performance in a circulation altered by cardiac ... -
Are fish oil omega-3 long-chain fatty acids and their derivatives peroxisome proliferator-activated receptor agonists?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-03-20)Background Peroxisome proliferator-activated receptors (PPARα, PPARγ, and PPARδ) are physiological sensors for glucose and lipid homeostasis. They are also the targets of synthetic drugs; such as fibrates as PPARα agonists which lower lipid level, and glitazones as PPARγ agonists which lower glucose level. As diabetes and metabolic diseases are often associated with high blood glucose and lipid ... -
Complete mitochondrial genome sequences of the Arctic Ocean codfishes Arctogadus glacialis and Boreogadus saida reveal oriL and tRNA gene duplications
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-05-27)We have determined the complete mitochondrial genome sequences of the codWshes Arctogadus glacialis and Boreogadus saida (Order Gadiformes, Family Gadidae). The 16,644 bp and 16,745 bp mtDNAs, respectively, contain the same set of 37 structural genes found in all vertebrates analyzed so far. The gene organization is conserved compared to other Gadidae species, but with one notable exception. ... -
Risk assessment of import and dissemination of intestinal pathogenic bacteria via fresh herbs and leafy vegetables from South-East Asia. Opinion of the Panel on Biological Hazards
(Research report; Forskningsrapport, 2008-06)Several studies have demonstrated that fresh herbs and green or leafy vegetables can be contaminated by intestinal pathogenic bacteria such as <i>Salmonella</i> spp. Although systematic surveys are probably not conducted in any countries some places, in recent years the Rapid Alert System for Food and Feed (RASFF) has received approximately 30 alerts annually on the detection of potentially pathogenic ... -
Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-08-15)Introduction: Acute lung injury often complicates severe sepsis. In Gram-negative sepsis, bacterial endotoxin activates both coagulation and inflammation. Enhanced lung vascular pressures and permeability, increased extravascular lung water content and deteriorated gas exchange characterize ovine endotoxin-induced lung injury, a frequently used model of acute lung injury. Recombinant human ... -
14th International Symposium on Cells of the Hepatic Sinusoid
(Book; Bok, 2008-08-31)Abstract book of the symposium -
Salmonella diarizonae hos dyr i Norge. Konsekvenser for dyr og mennesker.
(Research report; Forskningsrapport, 2008-09-09)S. diarizonae er et subspecies av Salmonella som påvises endemisk hos sau i enkelte regioner i Norge. Det er derfor stilt spørsmål om mikrobens potensielle og reelle betydning for både folke- og dyrehelsen. Det er også stilt spørsmål ved påstanden om at Norge har en tilnærmet salmonella-fri husdyrpopulasjon kan forsvares når S. diarizonae påvises relativt ofte hos sau i Norge i dag. Mattilsynet har ... -
Visualising vascular perfusion in isolated human abdominal flaps using dynamic infrared thermography (DIRT) and indocyanine green fluorescence video angiography (ICG-FA)
(Peer reviewed; Journal article; Tidsskriftsartikkel, 2008-10)This experimental study compared the direct technique indocyanine green fluorescence angiography (ICG-FA) and the indirect technique dynamic infrared thermography (DIRT) for visualising skin perfusion. Eight isolated human transverse abdominal skin flaps, obtained from female patients undergoing abdominoplasty, were used. A total of 19 selected vessels were individually perfused. Warm and cold ... -
Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-10-30)Background: Osteoclasts (OCs) are involved in rheumatoid arthritis and in several pathologies associated with bone loss. Recent results support the concept that some medicinal plants and derived natural products are of great interest for developing therapeutic strategies against bone disorders, including rheumatoid arthritis and osteoporosis. In this study we determined whether extracts of Emblica ... -
Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-12-01)Lupus nephritis is a major contributor to morbidity and mortality in systemic lupus erythematosus, but little is known about the pathogenic processes that underlie the progressive decay in renal function. A common finding in lupus nephritis is thickening of glomerular basement membranes associated with immune complex deposition. It has been speculated that alterations in the synthesis or ... -
The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay
(Journal article; Tidsskriftartikkel; Peer reviewed, 2008-12-19)<b>Background:</b> The fish pathogen Aliivibrio salmonicida is the causative agent of cold-water vibriosis in marine aquaculture. The Gram-negative bacterium causes tissue degradation, hemolysis and sepsis in vivo.<BR><BR> <b>Results:</b> In total, 4 286 protein coding sequences were identified, and the 4.6 Mb genome of A. salmonicida has a six partite architecture with two chromosomes and four ... -
EMMA 2-A MAGE-compliant system for the collaborative analysis and integration of microarray data
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009) -
Utvidet egenmelding : en vei mot riktigere sykefravær?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009) -
Low Sensitivity of the Formol-Ethyl Acetate Sedimentation Concentration Technique in Low-Intensity Schistosoma japonicum Infections
(Journal article; Tidsskriftartikkel, 2009) -
Do cancer patients with a poor prognosis use Complementary and Alternative Medicine more often than others?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009)Introduction: One reason for patients with cancer to use complementary and alternative medicine (CAM) is that their cancer cannot be cured by conventional therapy. The aim of the present study is to explore whether use of CAM is associated with survival prognosis in long-term survivors of cancer. Materials and methods: Cancer patients who were alive 5 years or more after diagnosis were chosen to ... -
In HPA 1a-immunized women the decrease in anti-HPA 1a antibody level during pregnancy is not associated with anti-idiotypic antibodies
(Journal article; Tidsskriftartikkel, 2009) -
Aneuploidy prediction and tumor classification with heterogeneous hidden conditional random fields
(Journal article; Tidsskriftartikkel; Peer reviewed, 2009)The heterogeneity of cancer cannot always be recognized by tumor morphology, but may be reflected by the underlying genetic aberrations. Array comparative genome hybridization (array-CGH) methods provide high-throughput data on genetic copy numbers, but determining the clinically relevant copy number changes remains a challenge. Conventional classification methods for linking recurrent alterations ... -
Kliniske studier av av yrkesbetinget løsemiddeleksponerte. Et systematisk litteratursøk
(Research report; Forskningsrapport, 2009)I Norge er det enighet om de overordnede kriteriene for å gi diagnosen løsemiddelskade. Likevel er det ikke utviklet en enhetlig og detaljert modell for utredning av slik skade. Nasjonalt kunnskapssenter for helsetjenesten har i samarbeid med de norske utredningsmiljøene for løsemiddelskade gjennomført et litteratursøk etter kliniske studier av personer med langvarig yrkesbetinget løsemiddeleksponering. ...
