Viser treff 1029-1048 av 1796

    • Management strategies for children with COVID-19: ESPR practical recommendations 

      Raissaki, Maria; Shelmerdine, Susan; Damasio, Beatrice; Toso, Seema; Kvist, Ola; Lovrenski, Jovan; Hirsch, Franz Wolfgang; Görkem, Süreyya Burcu; Paterson, Anne; Arthurs, Owen J.; Rossi, Andrea; van Schuppen, Joost; Petit, Philippe; Argyropoulou, Maria I.; Offiah, Amaka C.; Rosendahl, Karen; Caro-Domínguez, Pablo (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-03)
      During the outbreak of the COVID-19 pandemic, guidelines have been issued by international, national and local authorities to address management and the need for preparedness. Children with COVID-19 differ from adults in that they are less often and less severely affected. Additional precautions required in the management of children address their increased radiosensitivity, need for accompanying ...
    • Markers of extracellular matrix remodeling and systemic inflammation in patients with heritable thoracic aortic diseases 

      Seim, Bjørn Edvard; Holt, Margrethe Flesvig; Ratajska, Aleksandra; Michelsen, Annika Elisabet; Ringseth, Monica Myklebust; Halvorsen, Bente; Skjelland, Mona; Kvitting, John-Peder; Lundblad, Runar; Krohg-Sørensen, Kirsten; Osnes, Liv T. N.; Aukrust, Pål; Paus, Benedicte; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-20)
      Background: In approximately 20% of patients with thoracic aortic aneurysms or dissections a heritable thoracic aortic disease (HTAD) is suspected. Several monogenic connective tissue diseases imply high risk of aortic disease, including both non-syndromic and syndromic forms. There are some studies assessing inflammation and extracellular matrix remodeling in patients with non-hereditary aortic ...
    • Markers of neutrophil activation and neutrophil extracellular traps in diagnosing patients with acute venous thromboembolism: A feasibility study based on two VTE cohorts 

      Smith, Philip; Rosell, Axel; Farm, Maria; Bruzelius, Maria; Gatica, Katherina Aguilera; Mackman, Nigel; Odeberg, Jacob; Thålin, Charlotte (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-28)
      <b><p>Background</b> Venous thromboembolism (VTE) diagnosis would greatly benefit from the identification of novel biomarkers to complement D-dimer, a marker limited by low specificity. Neutrophil extracellular traps (NETs) have been shown to promote thrombosis and could hypothetically be used for diagnosis of acute VTE. <b><p>Objectives</b> To assess the levels of specific markers of ...
    • The marriage of sartorius and tensor fasciae latae in treating vascular prosthetic graft infections 

      Zoepke, Simone N.; de Weerd, Louis (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-20)
      Background: <br> Vascular prosthetic graft infection in the groin is associated with high morbidity and mortality. This article presents a case series on the use of 2 flaps in the treatment of this condition. <br>Methods:<br> Five patients, mean age 65 years (range, 49–74 years), with significant comorbidity were treated for an exposed and infected vascular prosthetic graft in the groin with a ...
    • The Master Study in Telemedicine and E-health at the University of Tromsø, Norway, 2005-2018 

      Wynn, Rolf; Ellingsen, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      In this paper we describe the Master Study in Telemedicine and E-health at the University of Tromsø, Norway. The study enrolled its first students in 2005 and was closed in 2018. We describe and discuss the background of the programme, its development and accomplishments and why it was closed. Hopefully, this narrative will be of use to other programmes focusing on e-health.
    • The Maternal and Paternal Effects on Clinically and Surgically Defined Osteoarthritis 

      Weldingh, Eirik; Johnsen, Marianne Bakke; Hagen, Kåre Birger; Østerås, Nina; Risberg, May Arna; Natvig, Bård; Christensen, Barbara Therese Slatkovsky; Fenstad, Anne Marie; Furnes, Ove; Nordsletten, Lars; Magnusson, Karin (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-25)
      <i>Objective</i> - It is currently unknown whether osteoarthritis (OA) is inherited mainly from the mother, father, or both. This study was undertaken to explore the effect of maternal and paternal factors on hip, knee, and hand OA in offspring.<p> <p><i>Methods</i> - Participants from the Musculoskeletal Pain in Ullensaker Study (MUST) (69% female; mean ± SD age 64 ± 9 years) and a Norwegian ...
    • Maternal cardiac function, uterine artery hemodynamics and natriuretic peptides at 22-24 weeks of gestation and subsequent development of hypertensive disorders of pregnancy 

      Liang, Huan; Vårtun, Åse; Flo, Kari; Widnes, Christian; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-26)
      <p><i>Introduction - </i>Maternal cardiac dysfunction as well as abnormal uterine artery (UtA) Doppler are associated with hypertensive disorders of pregnancy (HDP), but their relation is unclear. We investigated the correlation between maternal cardiac function, UtA hemodynamics and natriuretic peptides, and explored differences between women who subsequently developed HDP and those who did ...
    • Maternal functional hemodynamics in the second half of pregnancy: A longitudinal study 

      Vårtun, Åse; Flo, Kari; Wilsgaard, Tom; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-10)
      Objective: Cardiovascular response to passive leg raising (PLR) is useful in assessing preload reserve, but it has not been studied longitudinally during pregnancy. We aimed to investigate gestational age associated serial changes in maternal functional hemodynamics and establish longitudinal reference ranges for the second half of pregnancy. Materials and Methods: This was a prospective ...
    • Maternal mortality related to pulmonary embolism in the United States, 2003–2020 

      Farmakis, loannis T.; Barco, Stefano; Hobohm, Lukas; Brækkan, Sigrid Kufaas; Connors, Jean M.; Giannakoulas, George; Hunt, Beverley J.; Keller, Karsten; Mavromanoli, Anna C.; Trinchero, Alice; Konstantinides, Stavros V.; Valerio, Luca (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-23)
      BACKGROUND - Pulmonary embolism is a leading cause of maternal morbidity and mortality in Western countries. In the United States, pulmonary embolism–related mortality rates have plateaued in the general population after an initial decrease in the past 20 years.<p> <p>OBJECTIVE - This study aimed to describe the changes in pulmonary embolism–related maternal mortality rates in the United States ...
    • Maternal serum laeverin (aminopeptidase Q) measured in the first trimester of pregnancy does not predict preeclampsia 

      Pihl, Kasper; Sørensen, Steen; Nystad, Mona; Acharya, Ganesh; Jørgensen, Finn S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-22)
      <i>Objective</i>: The aim of this study was to compare the laeverin level in maternal serum from first trimester (11–14 weeks) of pregnancy between normal pregnancies and pregnancies that later developed preeclampsia (PE).<p><p> <i>Material and methods</i>: This was a case-cohort study. The laeverin concentration was measured in cases with preterm PE (<i>n</i> = 55), term PE (<i>n</i> = 95), and ...
    • Matrix metalloproteinase-9 mediated shedding of syndecan-4 in glomerular endothelial cells 

      Reine, Trine M.; Lanzalaco, Francesca; Kristiansen, Oddrun; Enget, Anne Randi; Satchell, Simon; Jenssen, Trond Geir; Kolset, Svein Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-31)
      <p><i>Background - </i>Diabetic nephropathy is the most common cause of end‐stage renal failure in the western world and Asia. The mechanisms are not fully elucidated, but disruption of glomerular endothelial glycocalyx and shedding of its components including syndecans has been implicated. <p><i>Aims - </i>We hypothesize that reduced glomerular filtration in diabetes is caused by disruption of ...
    • May Women with a Negative Co-Test at First Follow-Up Visit Return to 3-Year Screening after Treatment for Cervical Intraepithelial Neoplasia? 

      Skjeldestad, Finn Egil; Sørbye, Sveinung (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-08)
      Background: The Norwegian Cervical Cancer Screening Programme recommends that women treated for cervical intraepithelial neoplasia (CIN) only be returned to 3-year screening after receiving two consecutive negative co-tests, 6 months apart. Here we evaluate adherence to these guidelines and assessed the residual disease, using CIN3+ as the outcome. Methods: This cross-sectional study comprised ...
    • Measuring extravascular lung water. Animals and humans are not the same 

      Bjertnæs, Lars J.; Kirov, Mikhail; Kuzkov, Vsevolod V.; Fernandez-Mondejar, Enrique (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-07-24)
      The evolution of extravascular lung water (EVLW) monitoring is an important step forward in the hemodynamic assessment of critically ill patients.
    • Measuring the effects of sharing mHealth data during diabetes consultations: a mixed-method study protocol 

      Bradway, Meghan; Giordanengo, Alain; Joakimsen, Ragnar Martin; Hansen, Anne Helen; Grøttland, Astrid; Hartvigsen, Gunnar; Randine, Pietro; Årsand, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-10)
      <i>Background</i>: There is rising demand for health care’s limited resources. Mobile health (mHealth) could be a solution, especially for those with chronic illnesses such as diabetes. mHealth can increases patients’ options to self-manage their health, improving their health knowledge, engagement, and capacity to contribute to their own care decisions. However, there are few solutions for sharing ...
    • Medium-Term Results After Treatment of Recalcitrant Lateral Epicondylitis A Prospective, Randomized Study Comparing Open Release and Radiofrequency Microtenotomy 

      Meknas, Khaled; Al Hassoni, Thabit N; Miland, Åshild Odden; Castillejo, Miguel; Kartus, Jüri, SWEDEN (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Recalcitrant lateral epicondylitis (elbow extensor–origin tendinosis) is a common cause of elbow pain with many treatment options. In the present study, the medium-term results after open release and radiofrequency microtenotomy are reported. Hypothesis: Microtenotomy would provide long-term pain relief that was as good as the open release method. Study Design: Prospective, randomized ...
    • Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs 

      Birgisdottir, Åsa Birna; Mouilleron, Stephane; Bhujabal, Zambarlal; Wirth, Martina; Sjøttem, Eva; Evjen, Gry; Zhang, Wenxin; Lee, Rebecca; O'Reilly, Nicola; Tooze, Sharon A; Lamark, Trond; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-04)
      Autophagosome formation depends on a carefully orchestrated interplay between membrane-associated protein complexes. Initiation of macroautophagy/autophagy is mediated by the ULK1 (unc-51 like autophagy activating kinase 1) protein kinase complex and the autophagy-specific class III phosphatidylinositol 3-kinase complex I (PtdIns3K-C1). The latter contains PIK3C3/VPS34, PIK3R4/VPS15, BECN1/Beclin 1 ...
    • Menopausal hormone therapy and breast cancer risk: effect modification by body mass through life 

      Sandvei, Marie Søfteland; Vatten, Lars Johan; Bjelland, Elisabeth Krefting; Eskild, Anne; Hofvind, Solveig; Ursin, Giske; Opdahl, Signe (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-06)
      It is not known whether increased breast cancer risk caused by menopausal hormone therapy (HT) depends on body mass patterns through life. In a prospective study of 483,241 Norwegian women aged 50–69 years at baseline, 7656 women developed breast cancer during follow-up (2006–2013). We combined baseline information on recalled body mass in childhood/adolescence and current (baseline) body mass index ...
    • Mental health and health related quality of life in mitochondrial POLG disease 

      Hikmat, Omar; Vederhus, Bente Johanne; Benestad, Merete Roineland; Engeset, Ida Malen E.; Klingenberg, Claus; Rasmussen, Magnhild; Tallaksen, Chantal; Brodtkorb, Eylert; Elgen, Irene Bircow; Bindoff, Laurence (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-23)
      We aimed to assess the impact of POLG disease on mental health and quality of life in 15 patients using the Symptom Checklist-90-R (SCL-90-R)and Short-Form 36 HealthSurvey (RAND-36). Wefound increased scores in all nine subscales of SCL-90-R, particularly phobic anxiety, depression and somatization. Further, patients reported considerably lower scores in all RAND-36 domains. This study revealed a ...
    • The mental health consequences on children of the war in Ukraine: A commentary 

      Elvevåg, Brita; DeLisi, Lynn E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-18)
      The news from Ukraine is currently full of heart-wrenching stories accompanied by graphic images of civilian casualties and massacres that are telecast world-wide on a daily basis. It is hard to fathom the magnitude of the devastation and disruption to regular lives and everyday routines that war brings with it, the witnessing of countless deaths, the associated trauma of living in perpetual fear, ...
    • Mental health, challenging behaviour, diagnosis, and access to employment for people with intellectual disabilities in Norway 

      Pedersen, Erlend Refseth; Anke, Audny Gabriele Wagner; Langøy, Emmy Elizabeth; Olsen, Monica Isabel Benedikte; Søndenaa, Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-09)
      Background: Studies have found that presence of challenging behaviours and mental health problems limits employment for people with intellectual disabilities. This study investigates the associations between age, gender, living condition, level of intellec tual disability, diagnoses, behaviour, mental health, and employment in adults with intellectual disabilities in Norway.<p> <p>Method: A ...