Viser treff 1192-1211 av 1796

    • Oral health-related quality of life, impaired physical health and orofacial pain in children and adolescents with juvenile idiopathic arthritis – a prospective multicenter cohort study 

      Halbig, Josefine Mareile; Jönsson, Birgitta; Gil, Elisabeth Grut; Åstrøm, Anne-Kristine N; Rypdal, Veronika Gjertsen; Frid, Paula Hanna Therese; Augdal, Thomas Angell; Fischer, Johannes Maria; Cetrelli, Lena Elisabet; Rygg, Marite; Lundestad, Anette; Tylleskär, Karin Birgitta; Nordal, Ellen Berit (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-20)
      Background - Knowledge on oral health-related quality of life (OHRQoL) in children and adolescents with juvenile idiopathic arthritis (JIA) is limited, and longitudinal studies are lacking. We aimed to describe OHRQoL in children and adolescents with JIA compared to controls, and to explore the validity and internal consistency of the Early Childhood Oral Health Impact Scale (ECOHIS) and the Child ...
    • Osteoprotegerin is associated with major bleeding but not with cardiovascular outcomes in patients with acute coronary syndromes: Insights from the PLATO (Platelet Inhibition and Patient Outcomes) trial 

      Ueland, Thor; Åkerblom, Axel; Ghukasyan, Tatevik; Michelsen, Annika; Aukrust, Pål; Becker, Richard C.; Bertilsson, Maria; Himmelmann, Anders; James, Stefan K.; Siegbahn, Agneta; Storey, Robert F.; Kontny, Frederic; Wallentin, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-12)
      Background: <br>Elevated levels of osteoprotegerin, a secreted tumor necrosis factor–related molecule, might be associated with adverse outcomes in patients with coronary artery disease. We measured plasma osteoprotegerin concentrations on hospital admission, at discharge, and at 1 and 6 months after discharge in a predefined subset (n=5135) of patients with acute coronary syndromes in the PLATO ...
    • Outcome of 881 total hip arthroplasties in 747 patients 21 years or younger: data from the Nordic Arthroplasty Register Association (NARA) 1995-2016 

      Halvorsen, Vera Baasland; Fenstad, Anne Marie; Engesæter, Lars B.; Nordsletten, Lars; Overgaard, Søren; Pedersen, Alma B.; Kärrholm, Johan; MOHADDES, MAZIAR; Eskelinen, Antti; Mäkelä, Keijo T.; Röhrl, Stephan Maximillian (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-15)
      <p><i>Background and purpose — </i>The literature is scarce on the outcome of the youngest patients with total hip arthroplasties (THAs). We analyzed register data, revision risk, and related factors in patients 21 years or younger with THAs in the Nordic Arthroplasty Register Association (NARA). <p><i>Patients and methods — </i>We included all THA patients 21 years or younger reported during 1995 ...
    • Outcomes and predictors of functioning, mental health, and health-related quality of life in adults born with very low birth weight: a prospective longitudinal cohort study 

      Wollum, Arnt Erik Karlsen; Berdal, Elias Kjølseth; Iversen, Johanne Marie; Indredavik, Marit Sæbø; Evensen, Kari Anne Indredavik (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-03)
      Background - Very low birth weight (VLBW: ≤1500 g) is associated with multiple short and long-term complications. This study aimed to examine outcomes and predictors of functioning, mental health, and health-related quality of life in adults born with VLBW.<p> <p>Methods - In this prospective longitudinal cohort study, 67 VLBW and 102 control participants were assessed using the Adult Self-Report ...
    • Outcomes in pancreas transplantation with exocrine drainage through a duodenoduodenostomy versus duodenojejunostomy 

      Lindahl, Jørn Petter Hanto; Horneland, Rune; Nordheim, Espen; Hartmann, Anders; Aandahl, Einar Martin; Grzyb, Krzysztof; Haugaa, Håkon; Kjøsen, Gisle; Åsberg, Anders; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel, 2017-08-23)
      Until recently, pancreas transplantation has mostly been performed with exocrine drainage via duodenojejunostomy (DJ). Since 2012, DJ was substituted with duodenoduodenostomy (DD) in our hospital, allowing endoscopic access for biopsies. This study assessed safety profiles with DD versus DJ procedures and clinical outcomes with the DD technique in pancreas transplantation. DD patients (n = 117; 62 ...
    • Outpatient clinics treating substance use disorders in Northwest Russia and Northern Norway: a descriptive comparative study 

      Dahl, Helene M.; Rezvyy, Grigory; Bogdanov, Anatoly; Øiesvold, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-15)
      Both in Norway and Russia a considerable portion of the population have substance use disorders. However, the knowledge about outpatient services treating substance use disorders in Norway and Russia is limited. This study will describe and compare outpatient clinics treating substance use disorders in Arkhangelsk in Northwest Russia and in Bodø and Tromsø in Northern Norway on availability, ...
    • Overexpression of mir-20a-5p in tumor epithelium is an independent negative prognostic indicator in prostate cancer—a multi-institutional study 

      Stoen, Maria J.; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona I.; Ingebriktsen, Lise M.; Dønnem, Tom; Lombardi, Ana P. G.; Kilvaer, Thomas K.; Rasmussen Busund, Lill-Tove; Richardsen, Elin (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-14)
      <i>Objective</i>: assessing the prognostic role of miR-20a-5p, in terms of clinical outcome, in a large multi-institutional cohort study.<br><br> <i>Methods</i>: Tissue microarrays from 535 patients’ prostatectomy specimens were constructed. In situ hybridization was performed to assess the expression level of miR-20a-5p in different tissue subregions: tumor stroma (TS) and tumor epithelium (TE). ...
    • Overexpression of the HIF Hydroxylases PHD1, PHD2, PHD3 and FIH Are Individually and Collectively Unfavorable Prognosticators for NSCLC Survival 

      Andersen, Sigve; Dønnem, Tom; Stenvold, Helge; Al-Saad, Samer; Al-Shibli, Khalid Ibrahim; Busund, Lill-Tove; Bremnes, Roy M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Hypoxia induced factors (HIFs) are at the heart of the adaptive mechanisms cancer cells must implement for survival. HIFs are regulated by four hydroxylases; Prolyl hydroxylase (PHD)-1,-2,-3 and factor inhibiting HIF (FIH). We aimed to investigate the prognostic impact of these oxygen sensors in NSCLC. Tumor tissue samples from 335 resected stages I to IIIA NSCLC patients was obtained and tissue ...
    • Pacemaker implantation in small hospitals : complication rates comparable to larger centres 

      Haug, Bjørn; Kjelsberg, Kjærsti; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Some countries have a demography that makes it necessary to maintain relatively small pacemaker centres. We wanted to assess the quality of pacemaker surgery in two such hospitals. Through patient records we gathered information on ∼535 consecutive primary pacemaker implantations in two small pacemaker centres with 30 and 80 annual operations, respectively. All patients were followed for 3 years. ...
    • PAI-1 and t-PA/PAI-1 complex potential markers of fibrinolytic bleeding after cardiac surgery employing cardiopulmonary bypass. 

      Ozolina, A.; Strike, E.; Jaunalksne, I.; Krumina, A.; Bjertnæs, Lars J.; Vanags, I. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Enhanced bleeding remains a serious problem after cardiac surgery, and fibrinolysis is often involved. We speculate that lower plasma concentrations of plasminogen activator inhibitor – 1 (PAI-1) preoperatively and tissue plasminogen activator/PAI-1 (t-PA/PAI-1) complex postoperatively might predispose for enhanced fibrinolysis and increased postoperative bleeding. Totally 88 adult patients (mean ...
    • Pain and pressure pain thresholds in adolescents With chronic fatigue syndrome and healthy Controls: a cross-sectional study 

      Winger, Anette; Kvarstein, Gunnvald; Wyller, Vegard Bruun; Sulheim, Dag; Fagermoen, Frode Even; Småstuen, Milada Cvancarova; Helseth, Sølvi (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-10-06)
      Objectives<br> Although pain is a significant symptom in chronic fatigue syndrome (CFS), pain is poorly understood in adolescents with CFS. The aim of this study was to explore pain distribution and prevalence, pain intensity and its functional interference in everyday life, as well as pressure pain thresholds (PPT) in adolescents with CFS and compare this with a control group of healthy adolescents ...
    • Pain During Sex Before and After Surgery for Lumbar Disc Herniation - A Multicenter Observational Study 

      Holmberg, Siril Therese; Salvesen, Øyvind; Vangen-Lønne, Vetle; Hara, Sozaburo; Fredheim, Olav Magnus; Solberg, Tore; Jakola, Asgeir S; Solheim, Ole; Nygaard, Øystein Petter; Gulati, Sasha (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-15)
      <p>Study Design. Observational multicenter study. <p>Objective. The aim of this study was to evaluate changes in pain during sexual activity after surgery for lumbar disc herniation (LDH). <p>Summary of Background Data. There are limited data available on sexual function in patients undergoing surgery for LDH. <p>Methods. Data were retrieved from the Norwegian Registry for Spine Surgery. The ...
    • Pain tolerance after stroke: The Tromsø study 

      Melum, Tonje Anita; Årnes, Anders; Stigum, Hein; Stubhaug, Audun; Steingrímsdóttir, Ólöf Anna; Mathiesen, Ellisiv B.; Nielsen, Christopher Sivert (Journal article; Tidsskriftartikkel, 2023-05-11)
      Background: Stroke lesions might alter pain processing and modulation by affecting the widely distributed network of brain regions involved. We aimed to compare pain tolerance in stroke survivors and stroke-free persons in the general population, with and without chronic pain.<p> <p>Methods: We included all participants of the sixth and seventh wave of the population-based Tromsø Study who had ...
    • Pain tolerance in persons with recognized and unrecognized myocardial infarction: a population-based, cross-sectional study 

      Øhrn, Andrea Sofie Henriette Milde; Nielsen, Christopher Sivert; Schirmer, Henrik; Stubhaug, Audun; Wilsgaard, Tom; Lindekleiv, Haakon (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-21)
      <b>Background</b> Unrecognized myocardial infarction (MI) is a prevalent condition associated with a similar risk of death as recognized MI. It is unknown why some persons experience MI with few or no symptoms; however, one possible explanation is attenuated pain sensitivity. To our knowledge, no previous study has examined the association between pain sensitivity and recognition of MI. <b>Methods ...
    • Pain-relieving effectiveness, quality of life and tolerability of repeated capsaicin 8% patch treatment of peripheral neuropathic pain in Scandinavian clinical practice 

      Hansson, Per; Jensen, Troels Staehelin; Kvarstein, Gunnvald; Strömberg, Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-01)
      <p><i>Context - </i>Clinical trials have demonstrated the efficacy and safety of the capsaicin 8% patch in patients with peripheral neuropathic pain (PNP); however, few studies have assessed this treatment in a clinical practice. <p><i>Objective - </i>To determine whether treatment and re‐treatment with the capsaicin 8% patch reduce PNP intensity in clinical practice. <p><i>Methods - </i>Three ...
    • Palliative appropriateness criteria: external validation of a new method to evaluate the suitability of palliative radiotherapy fractionation 

      Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård; Dalhaug, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-10)
      Background Recently, the palliative appropriateness criteria (PAC) score, a novel metric to aid clinical decision-making between different palliative radiotherapy fractionation regimens, has been developed. It includes baseline parameters including but not limited to performance status. The researchers behind the PAC score analyzed the percent of remaining life (PRL) on treatment. The latter was ...
    • Palliative non-small cell lung cancer treatment and end-of-life care stratified by sex and childlessness: an important interplay in unmarried patients? 

      Nieder, Carsten; Aanes, Siv Gyda; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-22)
      Purpose To analyze the interplay of sex and presence of children in unmarried patients with non-small cell lung cancer, because previous studies suggested sex-related disparities. Adult children may participate in treatment decisions and provision of social support or home care.<p> <p>Methods Retrospective single-institution analysis of 186 unmarried deceased patients, managed according to ...
    • The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain 11 Medical and Health Sciences 1103 Clinical Sciences 

      Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem; Caraceni, Augusto; Laird, Barry J; Boland, Jason W.; Rossi, Romina; Garcia-Alonso, Elena; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Bjerkeset, Ellen; Bye, Asta; Lund, Jo-Åsmund; Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Brunelli, Cinzia; Damås, Jan Kristian; Mollnes, Tom Eirik; Kaasa, Stein; Klepstad, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-28)
      <i><p>Background</i>: Radiation therapy (RT) results in pain relief for about 6 of 10 patients with cancer induced bone pain (CIBP) caused by bone metastases. The high number of non-responders, the long median time from RT to pain response and the risk of adverse effects, makes it important to determine predictors of treatment response. Clinical features such as cancer type, performance status and ...
    • Palliative radiotherapy during the last month of life: Have COVID-19 recommendations led to reduced utilization? 

      Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård; Yobuta, Rosalba (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01)
      Background/Aim: The study aimed to evaluate practice changes in the time period of the early wave of the COVID-19 pandemic. Patients and Methods: This was a retrospective single institution study. We defined palliative radiotherapy (PRT) initiated before Saturday, March 14th as pre-COVID and PRT initiated later as during-COVID (through June 30th). Results: National COVID-19 recommendations ...
    • Palliative Radiotherapy for Non-metastatic Non-small-cell Lung Cancer: Impact of Blood Test Results on Survival 

      Nieder, Carsten; Imingen, Kristian Steinsvik (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03)
      Background/Aim: Non-small-cell lung cancer (NSCLC) not amenable to curative treatment can be managed with palliative thoracic radiation or chemoradiation, however, with variable success. This study evaluated the prognostic impact of the LabBM score [serum lactate dehydrogenase (LDH), C-reactive protein, albumin, hemoglobin, platelets] in 56 patients who were scheduled to receive at least 10 ...