Blar i tittel Artikler, rapporter og annet (klinisk medisin)
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Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-05)BACKGROUND In patients with lumbar spinal stenosis and degenerative spondylolisthesis, it is uncertain whether decompression surgery alone is noninferior to decompression with instrumented fusion. METHODS We conducted an open-label, multicenter, noninferiority trial involving patients with symptomatic lumbar stenosis that had not responded to conservative management and who had single-level ... -
Decompressive hemicraniectomy for space-occupying brain infarction: Nationwide population-based registry study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-14)Objective: We analyzed data from the Norwegian Stroke Registry (NSR) to study access to and outcomes of decompressive hemicraniectomy for brain infarction in a nationwide routine clinical setting. We also discretionary assessed whether the outcomes were comparable with those achieved in randomized controlled trials (RCTs), and whether the use was in accordance with guidelines. Methods: The NSR ... -
The decreasing prevalence of nonrefractive visual impairment in older Europeans: a meta-analysis of published and unpublished data
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-13)<p><i>Topic</i>: To estimate the prevalence of nonrefractive visual impairment and blindness in European persons 55 years of age and older.</p> <p><i>Clinical Relevance</i>: Few visual impairment and blindness prevalence estimates are available for the European population. In addition, many of the data collected in European population-based studies currently are unpublished and have not been ... -
Defining and Scoping Participatory Health Informatics - An eDelphi Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-14)Background - Health care has evolved to support the involvement of individuals in decision making by, for example, using mobile apps and wearables that may help empower people to actively participate in their treatment and health monitoring. While the term “participatory health informatics” (PHI) has emerged in literature to describe these activities, along with the use of social media for health ... -
Delayed clearance of triglyceride-rich lipoproteins in young, healthy obese subjects
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-15)Obesity is associated with the metabolic syndrome. The aims were, first, to study the postprandial triglyceride clearance in young, healthy obese subjects and, second, to investigate if fasting triglycerides can predict delayed postprandial triglyceride clearance. Eighteen apparently healthy, obese subjects with no clinical signs of metabolic disturbances participated. Controls were age‐ and ... -
Delayed leukocytosis after hard strength and endurance exercise. Aspects of regulatory mechanisms
(Journal article; Tidsskriftartikkel; Peer reviewed, 2003-12-11)Background: During infections, polymorphonuclear neutrophilic granulocytes (PMN) are mobilized from their bone marrow stores, travel with blood to the affected tissue, and kill invading microbes there. The signal(s) from the inflammatory site to the marrow are unknown, even though a number of humoral factors that can mobilize PMN, are well known. We have employed a standardized, non-infectious ... -
Delivery Room ST Segment Analysis to Predict Short Term Outcomes in Near-Term and Term Newborns
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-03)Background: ST-segment changes to the fetal electrocardiogram (ECG) may indicate fetal acidosis. No large-scale characterization of ECG morphology immediately after birth has been performed, but ECG is used for heart rate (HR) assessment. We aimed to investigate ECG morphology immediately after birth in asphyxiated infants, using one-lead dry-electrode ECG developed for HR measurement. Methods: ... -
Dental anxiety: A comparison of students of dentistry, biology and psychology
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-09-23)Dental anxiety is an important challenge for many patients and clinicians. It is thus of importance to know more about dental students’ own experiences with dental anxiety and their understanding of dental anxiety. The aim was to investigate differences in dental anxiety levels between dental students, psychology students, and biology students at a Norwegian university. -
Depressive symptoms in the general population: The 7th Tromsø Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-10)Background: The prevalence of depressive symptoms may differ in various age groups. The aim of the study was to investigate the point-prevalence of depressive symptoms in the adult general population and in various age groups. The impact of sex, marital status, education, and social support on depressive symptoms was also explored.<p> <p>Methods: The population ≥40 years in the city of Tromsø, ... -
Deriving semantic structure from category fluency: Clustering techniques and their pitfalls
(Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Assessing verbal output in category fluency tasks provides a sensitive indicator of cortical dysfunction. The most common metrics are the overall number of words produced and the number of errors. Two main observations have been made about the structure of the output, first that there is a temporal component to it with words being generated in spurts, and second that the clustering pattern may reflect ... -
Description of health-related rehabilitation service provision and delivery in randomized controlled trials: A topic review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-18)Objective: To determine how health-related rehabilitation services have been described in recently pub-lished randomized clinical trials, using the International Classification System for Service Organization in Health-Related Rehabilitation (ICSO-R 2.0) as a framework.<p><p> Methods: Medline was searched for English--language randomized clinical trials (RCTs) published between 1 January 2018 and ... -
Description of the prehospital emergency healthcare system in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-11-23)Background: Norway has a long coastline, steep mountains, and wide fjords, which presents some challenges to the prehospital emergency healthcare system. In recent years, the prehospital emergency medical services (EMS) have undergone significant changes, structurally, in terms of professionalisation of the services and in the education level of the personnel. In this article, we aim to describe ... -
Description of the prehospital emergency healthcare system in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-23)Background: Norway has a long coastline, steep mountains, and wide fjords, which presents some challenges to the prehospital emergency healthcare system. In recent years, the prehospital emergency medical services (EMS) have undergone significant changes, structurally, in terms of professionalisation of the services and in the education level of the personnel. In this article, we aim to describe the ... -
Design of the GutHeart—targeting gut microbiota to treat heart failure—trial: a Phase II, randomized clinical trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-07)<p><i>Aims</i>: Heart failure (HF) is a multifactorial disease. Current treatments target only a fraction of the putative pathophysiological pathways. In patients with HF, reduced cardiac output and congestion cause increased gut wall permeability. It has been suggested that leakage of microbial products is detrimental to the heart, at least partly through activation of systemic inflammatory pathways, ... -
Det enkle er ikke alltid det beste
(Chronicle; Kronikk, 2012)På slutten av 1950-tallet ble et nytt medikament introdusert på verdensmarkedet. Thalidomid ble raskt erklært som en mirakelmedisin. Stoffet virket beroligende, smertestillende og søvndyssende, og det skulle knapt ha bivirkninger. Den gode effekten på morgenkvalme gjorde at thalidomid ble særlig populært blant gravide. Konsekvensen ble katastrofal. -
Detecting order-disorder transitions in discourse : implications for schizophrenia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Abstract Several psychiatric and neurological conditions affect the semantic organization and content of a patient's speech. Specifically, the discourse of patients with schizophrenia is frequently characterized as lacking coherence. The evaluation of disturbances in discourse is often used in diagnosis and in assessing treatment efficacy, and is an important factor in prognosis. Measuring these ... -
Detection of Perforators Using Smartphone Thermal Imaging
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11)Letter to the Editor -
Detection of quebec polyomavirus dna in samples from different patient groups
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-18)Polyomaviruses infect many species, including humans. So far, 15 polyomaviruses have been described in humans, but it remains to be established whether all of these are genuine human polyomaviruses. The most recent polyomavirus to be detected in a person is Quebec polyomavirus (QPyV), which was identified in a metagenomic analysis of a stool sample from an 85-year-old hospitalized man. We used PCR ... -
Determinants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: a cross-sectional sub-study of NoFRACT
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-21)<i>Summary</i> - Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, alcohol intake and BMD, not SQ1–SQ3 fractures. SQ1–SQ3 fractures were associated with age, prior fractures, and lumbar spine BMD, but not TBS.<p><p> <i>Introduction</i> ... -
Developing Large-scale Electronic Patient Records Conforming to the openEHR Architecture
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014)