Viser treff 411-430 av 1796

    • The development of a tool to assess medical students’ non-technical skills–The Norwegian medical students’ non-technical skills (NorMS-NTS) 

      Prydz, Katrine; Dieckmann, Gerhard Peter; Musson, David; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-07)
      Purpose - New physicians need to master non-technical skills (NTS), as high levels of NTS have been shown to increase patient safety. It has also been shown that NTS can be improved through training. This study aimed to establish the necessary NTS for Norwegian medical students to create a tool for formative and summative assessments.<p> <p>Methods - Focus group interviews were conducted with ...
    • Development of post-pericardiotomy syndrome is preceded by an increase in pro-inflammatory and a decrease in anti-inflammatory serological markers 

      Snefjellå, Nora; Lappegård, Knut Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The post-pericardiotomy syndrome (PPS) is a common complication after cardiac surgery, occuring in 10-40% of patients. PPS may prolong hospitalization, and even serious complications like tamponade and constrictive pericarditis may occur. Early diagnosis and treatment may reduce morbidity. In 50 patients transferred to our hospital after cardiac surgery we found an increase in pro-inflammatory and ...
    • Development of quantitative assay for simultaneous measurement of purine metabolites and creatinine in biobanked urine by liquid chromatography-tandem mass spectrometry 

      Svistounov, Dmitri; Solbu, Marit Dahl; Jenssen, Trond Geir; Mathisen, Ulla Dorte; Hansen, Terkel; Elgstøen, Katja Benedikte Prestø; Zykova, Svetlana (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-20)
      Purine metabolism is essential for all known living creatures, including humans in whom elevated serum concentration of purine break-down product uric acid (UA) is probably an independent risk factor for mortality, type 2 diabetes and cardiovascular events. An automated multiplex assay that measures several purine metabolites could therefore prove useful in many areas of medical, veterinary and ...
    • Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension 

      Thorstensen, Christian W.; Clasen, Per-Erik; Rognstad, Stine; Haldsrud, Renate; Føreid, Siri; Helstrøm, Trine; Bergland, Ola Undrum; Halvorsen, Lene Vernås; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Høieggen, Aud; Gustavsen, Ingebjørg G.; Larstorp, Anne Cecilie Kjeldsen; Søraas, Camilla Lund; Opdal, Mimi Stokke (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-23)
      We developed three ultra-high pressure liquid chromatography coupled to mass spectrometry detection (UHPLCMS/MS) methods to quantify 25 antihypertensive drugs in serum samples. Patient-reported drug lists were collected, and drug concentrations were analysed in samples from 547 patients, half with uncontrolled hypertension, and all treated with ≥ 2 antihypertensive drugs. For sample preparation, ...
    • Diabetes on Twitter: A Sentiment Analysis 

      Gabarron, Elia; Dorronzoro, Enrique; Rivera-Romero, Octavio; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-19)
      Background: <br>Contents published on social media have an impact on individuals and on their decision-making. Knowing the sentiment towards diabetes is fundamental to understanding the impact that such information could have on people affected with this health condition and their family members. The objective of this study is to analyze the sentiment expressed in messages on diabetes posted ...
    • Diagnosing comorbidity in psychiatric hospital:challenging the validity of administrative registers 

      Øiesvold, Terje; Nivison, Mary; Hansen, Vidje; Skre, Ingunn; Østensen, Line; Sørgaard, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background This study will explore the validity of psychiatric diagnoses in administrative registers with special emphasis on comorbid anxiety and substance use disorders. Methods All new patients admitted to psychiatric hospital in northern Norway during one year were asked to participate. Of 477 patients found eligible, 272 gave their informed consent. 250 patients (52%) with hospital ...
    • Diagnostic accuracy of anti-3-[<sup>18</sup>F]-FACBC PET/MRI in gliomas 

      Karlberg, Anna Maria; Pedersen, Lars Kjelsberg; Vindstad, Benedikte Emilie; Skjulsvik, Anne Jarstein; Johansen, Håkon; Solheim, Ole Skeidsvoll; Skogen, Karoline; Kvistad, Kjell Arne; Bogsrud, Trond; Myrmel, Kristin Smistad; Giskeødegård, Guro F.; Ingebrigtsen, Tor; Berntsen, Erik Magnus; Eikenes, Live (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-30)
      Purpose - The primary aim was to evaluate whether anti-3-[<sup>18</sup>F]FACBC PET combined with conventional MRI correlated better with histomolecular diagnosis (reference standard) than MRI alone in glioma diagnostics. The ability of anti-3-[<sup>18</sup>F]FACBC to differentiate between molecular and histopathological entities in gliomas was also evaluated.<p> <p>Methods - In this prospective ...
    • Diagnostic Blood Biomarkers for Acute Pulmonary Embolism: A Systematic Review 

      Wikan, Vårin Eiriksdatter; Tøndel, Birgitte Gladsø; Morelli, Vania Maris; Brodin, Ellen Elisabeth; Brækkan, Sigrid Kufaas; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-06)
      (1) Background: The current diagnostic algorithm for acute pulmonary embolism (PE) is associated with the overuse of CT pulmonary angiography (CTPA). An additional highly specific blood test could potentially lower the proportion of patients with suspected PE that require CTPA. The aim was to summarize the literature on the diagnostic performance of biomarkers of patients admitted to an emergency ...
    • Diagnostic imaging and ionizing radiation exposure in a level 1 trauma centre population met with trauma team activation: a one-year patient record audit 

      Bågenholm, Anna; Løvhaugen, Pål; Sundset, Rune; Ingebrigtsen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-15)
      This audit describes ionizing and non-ionizing diagnostic imaging at a regional trauma centre. All 144 patients (males 79.2%, median age 31 years) met with trauma team activation from 1 January 2015 to 31 December 2015 were included. We used data from electronic health records to identify all diagnostic imaging and report radiation exposure as dose area product (DAP) for conventional radiography ...
    • Diagnostic laboratory testing for Charcot Marie Tooth disease (CMT): the spectrum of gene defects in Norwegian patients with CMT and its implications for future genetic test strategies. 

      Østern, Rune André Helland; Fagerheim, Toril; Hjellnes, Helene; Nygård, Bjørn; Mellgren, Svein Ivar; Nilssen, Øivind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      The importance of diagnosing and treating co-occurring psychiatric disorders among substance abusers in treatment has received much attention. The aim of this study was to investigate to which extent co-occurring psychiatric disorders are diagnosed in a clinical population of substance abusers, and which factors (including the use of MINI-Plus) that influence the diagnosing of co-occurring psychiatric ...
    • Diagnostic value of antibodies against mutated citrullinated vimentin for rheumatoid arthritis 

      Besada, Emilio; Nikolaisen, Cathrin; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      OBJECTIVES: To compare the diagnostic efficiency of anti-MCV, anti-CCP2 and RF detection for patients with RA. METHODS: Cross-sectional study of patients with established rheumatic disease: rheumatoid arthritis (RA; n=75), psoriatic arthritis (PsA; n=25), 27 patients with ankylosing spondylitis (AS; n=27) and connective tissue disease (CTD; n=17). Anti-CCP2, anti-MCV and RF were detected by ...
    • Diagnostikk av øyeinfeksjoner. Strategimøte nr. 32, 2018 

      Brekke, Hanne; Romstad, Monica Regine; Stubhaug, Tore Taksdal; Åsheim, Sandra Elena; Mengshoel, Anne Torunn (Research report; Forskningsrapport, 2018-04)
      Det 32. Strategimøte i regi av Referansegruppen for eksterne kvalitetsvurderinger i bakteriologi, mykologi og parasittologi omhandlet øyeinfeksjoner og ble avholdt 31.10.2018 på Gjestehuset Lovisenberg i Oslo. På møtet deltok 40 personer fra 20 av landets medisinskmikrobiologiske laboratorier.<p> <p>Ansvarlig programkomité, som også har ferdigstilt denne avsluttende rapporten, var Hanne Brekke, ...
    • Dialog og refleksjon. Festskrift til Tom Andersens 60 års dag 

      Anderson, Harlene; Flåm, Anna Margrethe; Talberg, Pål; Forsdahl, Anders; Gergen, Kenneth. J.; Hartviksen, Ivar; Hoffman, Lynn; Høyer, Georg; Kjellberg, Eva; Korvald, Erik; kristiansen, Unni; Lebenbaum, Peter; Lindseth, Anders; McNamee, Sheila; Mjøs, Ole. D.; Penn, Peggy; Reichelt, Ebbe. G.; Reichelt, Sissel; Seikkula, Jaakko; Aaltonen, Jukka; Alakare, Birgitta; Shotter, John; Katz, Arlene M.; Stensland, Per; Søgaard, Anne Johanne; Fønnebø, Vinjar; Wagner, Judith; Wifstad, Åge; Øverberg, Gudrun; Aaraas, Ivar; Njølstad, Inger (Research report; Forskningsrapport, 1996)
    • Dietary changes in early-stage breast cancer patients from pre-surgery and over the 12 months post-surgery 

      Brunvoll, Sonja Hjellegjerde; Thune, Inger; Bertheussen, Gro Falkener; Fjeldheim, Frøydis Nyborg; Flote, Vidar Gordon; Frydenberg, Hanne; Lundgren, Steinar; Skjerven, Helle; Lømo, Jon; Fagerland, Morten; McTiernan, Anne; Schlichting, Ellen; Hjartåker, Anette (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-19)
      The time after a breast cancer diagnosis is a potential period for making positive dietary changes, but previous results are conflicting. The main aim of the present study was to study breast cancer patients’ dietary changes during the 12 months post-surgery and from 12 months pre-surgery to 12 months post-surgery with repeated administration of a 7-d pre-coded food diary and an FFQ, respectively. ...
    • Dietary intake of marine n-3 polyunsaturated fatty acids and future risk of venous thromboembolism 

      Isaksen, Trond; Evensen, Line Holtet; Johnsen, Stein Harald; Jacobsen, Bjarne K.; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-13)
      <p><i>Background</i>: Studies on the association between long‐chained n‐3 polyunsaturated fatty acids (n‐3 PUFAs) and risk of venous thromboembolism (VTE) are conflicting, potentially due to challenges related to assessment of n‐3 PUFA intake and changes in diet during follow‐up.</p> <p><i>Objectives</i>: To investigate whether dietary intake of marine n‐3 PUFAs was associated with risk of incident ...
    • Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury 

      Mikolic, Ana; van Klaveren, David; Oude Groeniger, Joost; Wiegers, E; Lingsma, Hester F; Zeldovich, Marina; von Steinbüchel, Nicole; Maas, Andrew I.R.; Roeters van Lennep, Jeanine; Polinder, Suzanne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-19)
      Traumatic brain injury (TBI) is a significant cause of disability, but little is known about sex and gender differences after TBI. We aimed to analyze the association between sex/gender, and the broad range of care pathways, treatment characteristics, and outcomes following mild and moderate/severe TBI. We performed mixed-effects regression analyses in the prospective multi-center Collaborative ...
    • Differences in gene expression between first and third trimester human placenta : a microarray study. 

      Sitras, Vasilis; Fenton, Christopher Graham; Paulssen, Ruth H; Vårtun, Åse; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The human placenta is a rapidly developing organ that undergoes structural and functional changes throughout the pregnancy. Our objectives were to investigate the differences in global gene expression profile, the expression of imprinted genes and the effect of smoking in first and third trimester normal human placentas. Placental samples were collected from 21 women with uncomplicated pregnancies ...
    • Differences in implementation of family focused practice in hospitals: a cross-sectional study 

      Skogøy, Bjørg Eva; Maybery, Daryl; Ruud, Torleif; Sørgaard, Knut W.; Peck, Gro Christensen; Kufås, Elin; Stavnes, Kristin Anne; Thorsen, Eivind; Ogden, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-10)
      <p><i>Background</i>: Changes in Norwegian law and health policy require all health professionals to help safeguard the provision of information and follow-up for the children of parents with mental or physical illness, or substance abuse problems, to decrease their risk of psychosocial problems. There is a lack of knowledge on how the national changes have been received by hospital-based health ...
    • Differences in time-critical interventions and radiological examinations between adult and older trauma patients: A national register-based study 

      Cuevas-Østrem, Mathias; Wisborg, Torben; Røise, Olav; Jeppesen, Elisabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-07)
      BACKGROUND<p> <p>Older trauma patients are reported to receive lower levels of care than younger adults. Differences in clinical management between adult and older trauma patients hold important information about potential trauma system improvement targets. The aim of this study was to compare prehospital and early in-hospital management of adult and older trauma patients, focusing on time-critical ...
    • Differential profile of protumor immunological factors between the tumor site and the tumor-free site – predictive potential of IL-8 and COX2 for colorectal cancer and metastasis 

      Cui, Guanglin; Yuan, Aping; Pang, Zhigang; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-05)
      To study the role of host immune surveillance in the initiation and progression of colorectal cancer (CRC), a set of protumor immunological factors was determined by quantitative real-time PCR (q-PCR) between the primary tumor and the adjacent tumor-free site tissues in 63 patients with colorectal neoplasms. Results showed that expression levels of interleukin (IL)-1β, IL-6, IL-8, IL-17A, IL-23, and ...