Artikler, rapporter og annet (klinisk medisin): Recent submissions
Now showing items 1081-1100 of 1974
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Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood
(Journal article; Tidsskriftartikkel, 2019-07-25)<i>Aim</i> - To study the role of complement receptor 1 (CR1) for binding of <i>Escherichia coli (E. coli)</i> to erythrocytes, for leukocyte phagocytosis, oxidative burst and complement activation in human whole blood from a CR1 deficient (CR1D) patient and healthy controls with low, medium and high CR1 numbers.<p> <p><i>Methods</i> - Alexa-labelled bacteria were used to quantify ... -
Maternal cardiac function, uterine artery hemodynamics and natriuretic peptides at 22-24 weeks of gestation and subsequent development of hypertensive disorders of pregnancy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-26)<p><i>Introduction - </i>Maternal cardiac dysfunction as well as abnormal uterine artery (UtA) Doppler are associated with hypertensive disorders of pregnancy (HDP), but their relation is unclear. We investigated the correlation between maternal cardiac function, UtA hemodynamics and natriuretic peptides, and explored differences between women who subsequently developed HDP and those who did ... -
Automated analysis of fetal cardiac function using color tissue Doppler imaging in second half of normal pregnancy
(Journal article; Tidsskriftartikkel, 2018-02-26)<i>Objectives</i> - Color tissue Doppler imaging (cTDI) is a promising tool for the assessment of fetal cardiac function. However, the analysis of myocardial velocity traces is cumbersome and time‐consuming, limiting its application in clinical practice. The aim of this study was to evaluate fetal cardiac function during the second half of pregnancy and to develop reference ranges using an ... -
Explaining the association between anxiety disorders and alcohol use disorder: A twin study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-05)<p><i>Background - </i>It is unknown whether social anxiety disorder (SAD) has a unique association with alcohol use disorder (AUD) over and beyond that of other anxiety disorders, how the associations develop over time, and whether the associations are likely to be causal. <p><i>Methods - </i>Diagnoses of AUD, SAD, generalized anxiety disorder, panic disorder, agoraphobia, and specific phobias ... -
Characteristics of women with chronic pelvic pain referred to physiotherapy treatment after multidisciplinary assessment: a cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-31)<i>Background and aims</i> - Chronic pelvic pain (CPP) in women is a complex condition that can seriously impact health and quality of life. Clinical guidelines for CPP place great demands on healthcare professionals, as they require both specialized knowledge about the pelvic area and knowledge of the mechanisms of chronic pain. To ensure best possible assessment and treatment of these women it ... -
Adolescent self-harm and suicidal behavior and young adult outcomes in indigenous and non-indigenous people
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-18)The aim of this study was to examine the associations between self-harm and suicidal behavior in indigenous Sami and non-Sami adolescents and mental health and social outcomes in young adulthood. Data were obtained by linking the Norwegian Patient Registry (2008–2012), the National Insurance Registry (2003–2013), and the Norwegian Arctic Adolescent Health Study, a school-based survey inviting all ... -
The Impact of Cytokines on the Health-Related Quality of Life in Patients with Systemic Lupus Erythematosus
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-15)<i>Introduction</i>: Systemic lupus erythematosus (SLE) reduces the health-related quality of life (HRQoL), even during periods of disease quiescence. We investigated whether subclinical inflammation as reflected by cytokine levels is linked with reduced HRQoL. Methods: A cross-sectional study of SLE patients (<i>n</i> = 52, mean age 47.3, 86.5% female) who completed a Short Form Health Survey-36 ... -
Implementation of new guidelines in the prehospital services: a nationwide survey of Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-29)<i>Background</i> - A debate regarding the potential harmful effects of rigid neck collar and backboard usage among prehospital and hospital care providers in Norway provoked the development of an evidence-based guideline. “The Norwegian guideline for the prehospital management of adult trauma patients with potential spinal injury” was developed with rigorous scientific methods and published in ... -
Video consultations in medication overuse headache. A randomized controlled trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-17)<i>Objective</i> - To test the hypothesis that the effect of video consultations is noninferior to traditional consultations in managing patients with overuse headache (MOH).<p> <p><i>Materials and Methods</i> - Patients were recruited from referrals to a neurological clinic. In a randomized controlled trial (RCT), headache burden measured by headache impact test (HIT‐6) and frequency of ... -
Does cyberbullying occur simultaneously with other types of violence exposure?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-17)<i>Objective</i>: Our study aimed to verify whether cyberbullying victimization among adolescents occurs concomitantly with other forms of violence exposure (at home, at school and in the community).<p> <p><i>Methods</i>: A collaborative longitudinal study by Norwegian and Brazilian researchers was conducted in Itaboraí, a low-income city in southeast Brazil. At baseline, trained interviewers ... -
Forekomsten av angst- og depresjonssymptomer hos samiske og ikke-samiske elever i videregående skole i Finnmark i 1994 og 2014. [The prevalence of anxiety- and depression symptoms in Sami and non-Sami high school students in Finnmark county in 1994 and 2014]
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-09)Omtrent 15-20% av barn og unge i Norge vil i løpet av 3-18 års alderen oppleve symptomer på psykiske vansker og i hovedsak angst og depresjon. Flere internasjonale og nasjonale studier har vist at forekomsten av angst- og depressive symptomer blant ungdom har økt i løpet av de siste tiårene. Formålet med denne studien er å undersøke forekomsten av angst- og depresjonssymptomer blant samiske ... -
Physical activity and risk of recurrence and mortality after incident venous thromboembolism
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-15)<i>Background</i> - Limited data exist on the relationship between physical activity and major complications after incident venous thromboembolism (VTE).<p> <p><i>Objectives</i> - To investigate whether physical activity was associated with risk of recurrence and mortality in patients with VTE recruited from the general population.<p> <p><i>Methods</i> - Patients with incident VTE (n = 786) ... -
Utilizing Liposomal Quercetin and Gallic Acid in Localized Treatment of Vaginal Candida Infections
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-20)Vulvovaginal candidiasis (VVC) is a widely spread fungal infection that causes itching, pain and inflammation at the vaginal site. Although common, currently available treatment suffers from limited efficacy and high recurrence. In addition, the growing problem of resistance to azole drugs used in current treatments emphasizes the need for superior treatment options. Antimicrobial polyphenols are ... -
Post-Fracture Risk Assessment: Target The Centrally Sited Fractures First! A Sub-Study of NoFRACT
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-16)The location of osteoporotic fragility fractures adds crucial information to post‐fracture risk estimation. Triaging patients according to fracture site for secondary fracture prevention can therefore be of interest to prioritize patients considering the high imminent fracture risk. The objectives of this cross‐sectional study were therefore to explore potential differences between central (vertebral, ... -
Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-06)For those surviving encephalitis, the influence on daily life of patients and their relatives may be substantial. In contrast, the prognosis after aseptic meningitis (ASM) is considered good. In this prospective study in patients with encephalitis (n = 20) and ASM (n = 46), we show that both groups experienced reduced Health Related Quality of Life (HRQoL) at two months after discharge, and that ... -
Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-05)In observational studies, vitamin D deficiency is a risk factor for low bone density and future fractures, whereas a causal relation has been difficult to show in randomized controlled trials (RCTs). Similarly, vitamin D deficiency has been associated with increased bone turnover, but RCTs with vitamin D have not shown conclusive effects. This could be due to inclusion of vitamin D sufficient subjects ... -
Delayed clearance of triglyceride-rich lipoproteins in young, healthy obese subjects
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-15)Obesity is associated with the metabolic syndrome. The aims were, first, to study the postprandial triglyceride clearance in young, healthy obese subjects and, second, to investigate if fasting triglycerides can predict delayed postprandial triglyceride clearance. Eighteen apparently healthy, obese subjects with no clinical signs of metabolic disturbances participated. Controls were age‐ and ... -
Postprandial leptin and adiponectin in response to sugar and fat in obese and normal weight individuals
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-11)<p><i>Purpose - </i>Adipokines produced by white adipose tissue are central in the development of lifestyle diseases. Individuals in industrialized countries spend a substantial part of life in the non-fasting, postprandial state, which is associated with increased oxidation and inflammation. The aim was to study postprandial adiponectin and leptin levels after an oral fat tolerance test (OFTT) and ... -
Characterization of gut microbiota composition and functions in patients with chronic alcohol overconsumption
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-20)Excessive alcohol intake can alter the gut microbiota, which may underlie the pathophysiology of alcohol-related diseases. We examined gut microbiota composition and functions in patients with alcohol overconsumption for >10 years, compared to a control group of patients with a history of no or low alcohol intake. Faecal microbiota composition was assessed by 16S rRNA sequencing. Gut microbiota ... -
Weight loss and BMI criteria in GLIM's definition of malnutrition is associated with postoperative complications following abdominal resections – Results from a National Quality Registry
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-20)<i>Background & aims</i> - Although malnutrition is thought to be common among patients with intraabdominal diseases and is recognized as a risk factor for postoperative complications, diagnostic criteria for malnutrition have not been consistent. Thus, the Global Leadership Initiative in Malnutrition (GLIM) has recently published new criteria for malnutrition. The aims of this study were to investigate ...