Background:Telemedicine services are considered essential for improving the accessibility, quality and efficiency of the healthcare services in developing countries. With these expectations, government of Nepal has implemented a rural-telemedicine program in thirty peripheral district hospitals to improve the accessibility of specialist health services. Telemedicine can be appropriate to the ...

Postoperative sårinfeksjoner fører til økt sykelighet og dødelighet. Ventilasjonssystem i operasjonsstuer er én av mange faktorer som kan påvirke infeksjonsforekomst. Hvilket ventilasjonssystem som er best på å forebygge infeksjoner i operasjonssår har vært diskutert i mange år.<p> <p>Vi har utarbeidet en forenklet metodevurdering for å undersøke effekten av laminær ventilasjon (LAF) på infeksjonsforekomst. ...

Background: We present a method that utilizes DNA methylation profiling for prediction of the cytogenetic subtypes of acute lymphoblastic leukemia (ALL) cells from pediatric ALL patients. The primary aim of our study was to improve risk stratification of ALL patients into treatment groups using DNA methylation as a complement to current diagnostic methods. A secondary aim was to gain insight into ...

<p><i>Background:</i> Knowledge of comorbid disorders is important to optimize therapy for multiple sclerosis (MS), but data are limited. The aim of this study was to assess comorbidity in persons with MS living in Nordland County on January 1, 2017. <p><i>Methods:</i> Data were retrieved from the Norwegian Patient Registry (2008-2017) and validated through review of electronic hospital charts ...

The doctor-patient relationship has been the cornerstone of medical practice. As e-health is coming to play an increasingly important role, it is necessary to consider how e-health can draw on, integrate and safeguard aspects of this relationship and thereby improve services and engage patients.

<p><i>Objective:</i> This study used meta-analysis to assess disparities in cardiovascular disease (CVD) screening and treatment in people with mental disorders, a group that has elevated CVD incidence and mortality. <p><i>Methods:</i> The authors searched PubMed and PsycInfo through July 31, 2020, and conducted a random-effect meta-analysis of observational studies comparing CVD screening and ...

Purpose: The purpose of this study was to identify factors associated with the initiation or continuation of systemic treatment after brain irradiation. The outcome of interest was a utilization rate of at least 75%, given that active extracranial disease is common in patients with brain metastases. If left untreated, extracranial disease limits survival, regardless of successful local treatment of ...

A drop in arterial oxygen content activates fetal chemoreflex including an increase in sympathetic activity leading to peripheral vasoconstriction and redistribution of blood flow to protect the brain, myocardium, and adrenal glands. By using a chronically instrumented fetal sheep model with intact placental circulation at near-term gestation, we investigated the relationship between peripheral ...

Polyphosphate is a procoagulant inorganic polymer of linear-linked orthophosphate residues. Multiple investigations have established the importance of platelet polyphosphate in blood coagulation; however, the mechanistic details of polyphosphate homeostasis in mammalian species remain largely undefined. In this study, xenotropic and polytropic retrovirus receptor 1 (XPR1) regulated polyphosphate in ...