Blar i forfatter Norges arktiske universitetsmuseum "Oskolkov, Nikolay"

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    • Evolutionary consequences of genomic deletions and insertions in the woolly mammoth genome 

      van der Valk, Tom; Dehasque, Marianne; Chacón-Duque, J. Camilo; Oskolkov, Nikolay; Vartanyan, Sergey; Heintzman, Peter D.; Pečnerová, Patrícia; Díez-del-Molino, David; Dalén, Love (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-01)
      Woolly mammoths had a set of adaptations that enabled them to thrive in the Arctic environment. Many mammoth-specific single nucleotide polymorphisms (SNPs) responsible for unique mammoth traits have been previously identified from ancient genomes. However, a multitude of other genetic variants likely contributed to woolly mammoth evolution. In this study, we sequenced two woolly mammoth genomes and ...

    • Historical RNA expression profiles from the extinct Tasmanian tiger 

      Mármol-Sánchez, Emilio; Fromm, Bastian; Oskolkov, Nikolay; Pochon, Zoé; Kalogeropoulos, Panagiotis; Eriksson, Eli; Biryukova, Inna; Sekar, Vaishnovi; Ersmark, Erik; Andersson, Björn; Dalén, Love; Friedländer, Marc R. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-18)
      Paleogenomics continues to yield valuable insights into the evolution, population dynamics, and ecology of our ancestors and other extinct species. However, DNA sequencing cannot reveal tissue-specific gene expression, cellular identity, or gene regulation, which are only attainable at the transcriptional level. Pioneering studies have shown that useful RNA can be extracted from ancient specimens ...